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Fever of unknown origin. A changing clinical spectrum and a diagnostic challenge
This issue of Case Reports presents two cases of fever of unknown origin (FUO) that illustrate the etiological diversity and diagnostic complexity of this condition.
Moisés Casarrubias-Ramírez
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Idiopathic Polyclonal Plasmacytosis Presenting as Fever of Unknown Origin
An elderly male, after being flagged to have fever of unknown origin, was found to have plasmacytosis on bone marrow examination. On immunophenotyping, the proliferation was confirmed as polyclonal. No associated underlying condition such as infection or
Vivek Pal Singh, Ashutosh Garg
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Diagnostic Use of Serum Ferritin Levels to Differentiate Infectious and Noninfectious Diseases in Patients with Fever of Unknown Origin [PDF]
Background and study aim: Fever of unknown origin (FUO) constitutes one of the greatest challenges of clinical practice. It's defined as fever more than three weeks with fever above 38.3ºC on several occasions which remains undiagnosed after 3 days of ...
Rania Sobh +2 more
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An 18-year-old male was admitted for his second induction chemotherapy treatment for an acute lymphoblastic leukaemia with cyclophosphamide, cytarabine, and mercaptopurine.
Ignacio Martín Santarelli +6 more
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Hemophagocytic lymphohistiocytosis (HLH) is a rare and life‐threatening clinical syndrome, which may present with FUO. The possible diagnosis of HLH must be considered in the differential diagnosis when a patient presents with FUO.
Atousa Hakamifard +2 more
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Etiology and clinical characteristics of fever of unknown origin in children: a 15-year experience in a single center [PDF]
PurposeFever is one of the most common symptoms in children. In previous studies, infectious disease was the most common cause of pediatric fever of unknown origin (FUO).
Yi-Seul Kim +4 more
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Recurrent fever of unknown origin: An overlooked symptom of Fabry disease
Objective Fabry disease (FD) is a rare X‐linked lysosomal storage disorder due to the absent or deficient activity of lysosomal hydrolase a‐galactosidase A (α‐Gal A), which leads to the accumulation of its substrates in various organs and tissues ...
Yi Luo, Di Wu, Min Shen
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Objective: To present a unique case of intravascular lymphoma of the inferior turbinate because of its rarity, unusual clinical presentation and difficulty in establishing a diagnosis.
Milabelle B. Lingan, Francis V. Roasa
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Familial Mediterranean fever presenting as fever of unknown origin in Korea [PDF]
Familial Mediterranean fever (FMF) is the most common Mendelian autoinflammatory disease, characterized by uncontrolled activation of the innate immune system that manifests as recurrent brief fever and polyserositis (e.g., peritonitis, pleuritic, and ...
Jun Hee Lee +6 more
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