Results 61 to 70 of about 74,966 (263)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Low-Crosstalk High-Order Mode Silicon Fiber-Chip Coupler by Utilizing Apodized Double Part Gratings With Mode Selective Trident

IEEE Photonics Journal, 2023
We propose and experimentally demonstrate a silicon integrated high-order mode fiber-chip coupler. By utilizing a structure of apodized double-part gratings with mode selective trident, TE1 mode can be coupled with low mode crosstalk.
Weilun Zhang, Mengyuan Ye, Yunlong Li, Li Liu, Xiangyu Guo, Yu Yu   +5 more
doaj   +1 more source

Few-mode fiber based optical sensors

Optics Express, 2015
Few-mode fibers (FMFs) have found applications in optical communications and sensors with attractive features that standard single mode fiber (SSMF) do not possess. We report our recent progress on FMF based optical sensors, and show the potential of utilizing the spatial dimension for multi-parameter sensing with discrimination capability.
An, Li, Yifei, Wang, Qian, Hu, William, Shieh   +3 more
openaire   +2 more sources

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Recent Progress in Distributed Brillouin Sensors Based on Few-Mode Optical Fibers

Sensors, 2021
Brillouin scattering is a dominant inelastic scattering observed in optical fibers, where the energy and momentum transfer between photons and acoustic phonons takes place.
Yong Hyun Kim, Kwang Yong Song
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Optimization of Transverse OAM Transmission through Few-Mode Fiber

Photonics
Spatiotemporal optical vortex (STOV) wavepacket is a new type of vortex optical field carrying transverse orbital angular momentum (OAM). Due to the presence of imbalanced dispersion and diffraction phase, the STOV pulse undergoes fragmentation during ...
Chong Zhang, Qian Cao, Qiwen Zhan
doaj   +1 more source

Few-Mode Multicore Fibers and Fiber Devices

Asia Communications and Photonics Conference, 2017
This tutorial will cover the design and fabrication of few-mode fibers and few-mode fiber devices for space-division multiplexing for both long-haul and short-reach applications.
openaire   +3 more sources