Results 41 to 50 of about 64,820 (213)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Mode-Enhanced Surface Plasmon Resonance in Few-Mode Fibers via Dual-Groove Architecture
PhotonicsWe propose a dual-groove few-mode fiber surface plasmon resonance sensor that exploits the LP11 mode for enhanced plasmonic sensing. The device incorporates two physically separated grooves with distinct metallic coatings, enabling dual-channel operation
Qin Wu +4 more
doaj +1 more source
Gain Equalization for Few-Mode Erbium-Doped Fiber Amplifiers via Strong Mode Coupling
Applied Sciences, 2022 Few-mode erbium-doped fiber amplifiers (FM-EDFAs) are one of the most important optical subsystems for successful space division multiplexed transmission systems.
Yaping Liu +4 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Distributed Transverse Stress Sensor Based on Mode Coupling in Weakly-Coupled FMF
IEEE Photonics Journal, 2022 Distributed optical fiber sensors (DOFSs) have faced the challenge of measuring transverse stress along the fiber and the current main approach has been based on polarization coupling effect in polarization-maintaining fibers (PMFs), which has short ...
Junchi Jia +10 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
IEEE Access, 2022 An air-trenches/holes assisted depressed-core few-mode fiber (AT-AH-DC-FMF) that features some asymmetrical air trenches, air holes and a depressed step-index core is proposed in this paper.
Miaofang Zhou +5 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source