Results 71 to 80 of about 5,447,837 (291)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Few-mode fiber based optical sensors

Optics Express, 2015
Few-mode fibers (FMFs) have found applications in optical communications and sensors with attractive features that standard single mode fiber (SSMF) do not possess. We report our recent progress on FMF based optical sensors, and show the potential of utilizing the spatial dimension for multi-parameter sensing with discrimination capability.
An, Li, Yifei, Wang, Qian, Hu, William, Shieh   +3 more
openaire   +2 more sources

Characterization of few mode fibers by OLCI technique [PDF]

2014 The European Conference on Optical Communication (ECOC), 2014
All LP modes of a few mode fiber are simultaneously characterized using phase-sensitive optical low-coherence interferometry. The differential modal group delay and absolute chromatic dispersion values of each mode are retrieved from a single measurement without spatial mode transformers.
R. Gabet, E. Le Cren, Cang Jin, Michel Gadonna, Bora Ung, Yves Jaouën, Monique Thual, Sophie LaRochelle   +7 more
openaire   +1 more source

Depressed clad hollow optical fiber with fundamental LP01 mode cut-off

, 2006
We propose a depressed clad hollow optical fiber with fundamental (LP01) mode cut-off suitable for high power short-wavelength, especially three-level, fiber laser operation by introducing highly wavelength dependent losses at longer wavelengths. The cut-
Codemard, C., Nilsson, J., Y. Jeong, Dupriez, P., Soh, D.B.S., Sahu, J., D.B.S. Soh, C. Codemard, Yoo, S., J. Kim, S. Yoo, Jeong, Y., Kim, J., J. Nilsson, J. K. Sahu, P. Dupriez   +15 more
core   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Strain and temperature sensors using multimode optical fiber Bragg gratings and correlation signal processing [PDF]

, 2002
Multimode fiber optic Bragg grating sensors for strain and temperature measurements using correlation signal processing methods have been developed. Two multimode Bragg grating sensors were fabricated in 62/125 m graded-index silica multimode fiber ...
Jones, BE, Jackson, PR, Lim, J, Yang, QP
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Single-mode fiber length for wavefront filtering

, 2008
Stellar nulling interferometry offers the possibility of direct imaging of extrasolar planets necessary for the detection of extra-terrestrial life. Achieving optimum performance from the interferometers requires that the wavefronts of light reaching the
Dasgupta, Sonali, Broderick, N.G.R., Richardson, D.J.   +2 more
core   +1 more source

Recent progress in the development of few mode fiber amplifiers

, 2015
We review the performances of both core and cladding pumped few-mode erbium doped fiber amplifiers supporting 6 spatial modes (4 mode groups) which incidentally the highest mode count demonstrated to ...
Alam, S.U., Richardson, R.J., Jung, Y., Kang, Q., Poletti, F., Sahu, J.K.   +5 more
core   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source