Results 61 to 70 of about 63,682 (291)

Gain Equalization for Few-Mode Erbium-Doped Fiber Amplifiers via Strong Mode Coupling

Applied Sciences, 2022
Few-mode erbium-doped fiber amplifiers (FM-EDFAs) are one of the most important optical subsystems for successful space division multiplexed transmission systems.
Yaping Liu, Zhiqun Yang, Xutao Wang, Yongmin Jung, Lin Zhang   +4 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Distributed Transverse Stress Sensor Based on Mode Coupling in Weakly-Coupled FMF

IEEE Photonics Journal, 2022
Distributed optical fiber sensors (DOFSs) have faced the challenge of measuring transverse stress along the fiber and the current main approach has been based on polarization coupling effect in polarization-maintaining fibers (PMFs), which has short ...
Junchi Jia, Yu Yang, Mingqing Zuo, Jian Cui, Yuyang Gao, Jinyi Yu, Huang Yu, Zhenrong Zhang, Zhangyuan Chen, Yongqi He, Juhao Li   +10 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Mode-Enhanced Surface Plasmon Resonance in Few-Mode Fibers via Dual-Groove Architecture

Photonics
We propose a dual-groove few-mode fiber surface plasmon resonance sensor that exploits the LP11 mode for enhanced plasmonic sensing. The device incorporates two physically separated grooves with distinct metallic coatings, enabling dual-channel operation
Qin Wu, Xiao Liang, Zhaoxin Geng, Shuo Liu, Jia Liu   +4 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Design of Air-Trenches/Holes Assisted Depressed-Core 12-Mode Fiber for Less MIMO Space Division Multiplexing

IEEE Access, 2022
An air-trenches/holes assisted depressed-core few-mode fiber (AT-AH-DC-FMF) that features some asymmetrical air trenches, air holes and a depressed step-index core is proposed in this paper.
Miaofang Zhou, Ping Jiang, Huajun Yang, Weinan Caiyang, Yan Qin, Yifan Zheng   +5 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Observing mode-dependent wavelength-to-time mapping in few-mode fibers using a single-photon detector array

APL Photonics, 2020
Wavelength-to-time mapping (WTM)—stretching ultrashort optical pulses in a dispersive medium such that the instantaneous frequency becomes time-dependent—is usually performed using a single-mode fiber.
Harikumar K. Chandrasekharan, Katjana Ehrlich, Michael G. Tanner, Dionne M. Haynes, Sebabrata Mukherjee, Tim A. Birks, Robert R. Thomson   +6 more
doaj   +1 more source