Improved Dissolution Rate and Intestinal Absorption of Fexofenadine Hydrochloride by the Preparation of Solid Dispersions: In Vitro and in Situ Evaluation [PDF]
The objective of this study was to enhance dissolution and permeation of a low soluble, absorbable fexofenadine hydrochloride (FFH) by preparing solid dispersions using polyethylene glycol 20,000 (PEG 20,000) and poloxamer 188 as carriers.
Dinesh Nyavanandi +2 more
exaly +4 more sources
Application of green first derivative synchronous spectrofluorometric method for quantitative analysis of fexofenadine hydrochloride and pseudoephedrine hydrochloride in pharmaceutical preparation and spiked human plasma [PDF]
Fexofenadine hydrochloride and pseudoephedrine hydrochloride are prescribed in a combined dosage form for the treatment of allergic rhinitis. In the present work, a sensitive synchronous fluorescence spectroscopic method was applied in conjunction with ...
Sherif Ramzy +2 more
doaj +2 more sources
Insights into urticaria in pediatric and adult populations and its management with fexofenadine hydrochloride [PDF]
Objective The present narrative review provides a comprehensive update of the current knowledge on urticaria, both in adult and pediatric populations, and on the safety and efficacy of fexofenadine hydrochloride (HCl) as a treatment option. Data source A
Ignacio J. Ansotegui +7 more
doaj +2 more sources
Effect of fexofenadine hydrochloride on allergic rhinitis aggravated by air pollutants [PDF]
In recent decades, seasonal allergic rhinitis (SAR) prevalence has increased and recent studies have shown that air pollutants, such as diesel exhaust particles (DEP), can increase inflammatory and allergic biomarkers.
Anne K. Ellis +4 more
doaj +2 more sources
New pencil graphite electrodes for potentiometric determination of fexofenadine hydrochloride and montelukast sodium in their pure, synthetic mixtures, and combined dosage form [PDF]
This paper introduces the first electrochemical approach for the determination of Fexofenadine hydrochloride and Montelukast sodium as a combined form by constructing three new graphite electrodes coated with a polymeric membrane. The first electrode was
Dania Nashed +2 more
doaj +2 more sources
Solid Form and Phase Transformation Properties of Fexofenadine Hydrochloride during Wet Granulation Process [PDF]
The quality control of drug products during manufacturing processes is important, particularly the presence of different polymorphic forms in active pharmaceutical ingredients (APIs) during production, which could affect the performance of the formulated
Suye Li +5 more
doaj +2 more sources
Cubosomes for Enhancing Intestinal Absorption of Fexofenadine Hydrochloride: In situ and in vivo Investigation [PDF]
Amal A Sultan, Nourhan F El Nashar, Shimaa M Ashmawy, Gamal M El Maghraby Department of Pharmaceutical Technology, College of Pharmacy, University of Tanta, Tanta, EgyptCorrespondence: Amal A Sultan, Department of Pharmaceutical Technology, College of ...
Sultan AA +3 more
doaj +2 more sources
Formulation and Bioequivalence Evaluation of a Miniaturized Fexofenadine Hydrochloride Tablet [PDF]
Background: Fexofenadine hydrochloride (FEX) is widely used to treat allergic rhinitis. However, poor solubility, high cohesiveness, and risk of polymorphic transformation present significant formulation challenges.
Woo-Yul Song +11 more
doaj +2 more sources
Enhancement of the Oral Bioavailability of Fexofenadine Hydrochloride via Cremophor® El-Based Liquisolid Tablets [PDF]
Purpose: The current work aimed to develop promising Fexofenadine hydrochloride (FXD) liquisolid tablets able to increase its oral bioavailability and shorten time to reach maximum plasma concentrations (Tmax).
Soad Ali Yehia +3 more
doaj +2 more sources
Development of validated stability-indicating chromatographic method for the determination of fexofenadine hydrochloride and its related impurities in pharmaceutical tablets [PDF]
A simple reversed phase high performance liquid chromatographic method with diode array detector (HPLC-DAD) has been developed and subsequently validated for the determination of fexofenadine hydrochloride (FEX) and its related compounds; keto ...
Maher Hadir M +2 more
doaj +2 more sources

