Results 1 to 10 of about 267 (107)

Quantitative Assessment of the Relevance of Organic-Anion-Transporting-Polypeptide 1B1 and 2B1 Polymorphisms in Fexofenadine Pharmacokinetic Variants via Pharmacometrics

Journal of Pharmaceutical Analysis, 2023
Fexofenadine is useful in various allergic disease treatment. However, the pharmacokinetic variability information and quantitative factor identification of fexofenadine are very lacking.
Yong-Bok Lee, Seung-Hyun Jeong, Ji-Hun Jang   +2 more
exaly   +3 more sources

Cubosomes for Enhancing Intestinal Absorption of Fexofenadine Hydrochloride: In Situ and in Vivo Investigation

International Journal of Nanomedicine, 2022
Amal A Sultan, Nourhan F El Nashar, Shimaa M Ashmawy, Gamal M El Maghraby Department of Pharmaceutical Technology, College of Pharmacy, University of Tanta, Tanta, EgyptCorrespondence: Amal A Sultan, Department of Pharmaceutical Technology, College of ...
Gamal M El Maghraby, Shimaa M Ashmawy, Amal A Sultân   +2 more
exaly   +2 more sources

The effect of treatment with fexofenadine and fluticasone propionate on the gene expression levels of Th9 transcription factors in patients with allergic rhinitis

Heliyon, 2021
T helper-9 (Th9) is a new T cell subset involved in allergic rhinitis (AR) pathogenesis. Fexofenadine and fluticasone propionate are the first effective line of AR treatment.
Ali asghar Askari, Parisa Feizollahi, Alireza Rezaiemanesh, Farhad Salari, Ali Gorgin Karaji   +4 more
doaj   +1 more source

Chronic ingestion of H1-antihistamines increase progression of atherosclerosis in apolipoprotein E-/- mice. [PDF]

PLoS ONE, 2014
Although increased serum histamine levels and H1R expression in the plaque are seen in atherosclerosis, it is not known whether H1R activation is a causative factor in the development of the disease, or is a host defense response to atherogenic signals ...
Vineesh V Raveendran, Donald D Smith, Xiaoyu Tan, Matthew E Sweeney, Gregory A Reed, Colleen A Flynn, Ossama W Tawfik, Ginger Milne, Kottarappat N Dileepan   +8 more
doaj   +1 more source

Novel nano-leveled green switch-off fluorimetric technique for the determination of fexofenadine drug using Cilefa Pink B, a biological dye; raw material, dosage forms, and in vitro application; system kinetic study

Talanta Open, 2022
As a second-generation antihistamine, fexofenadine hydrochloride is prescribed to patients with allergic rhinitis and chronic urticaria to relieve their allergy symptoms.
Ahmed A. Hamad
doaj   +1 more source

Severity of coeliac disease and clinical management study when using a non-metabolised medication: a phase I pharmacokinetic study

BMJ Open, 2023
Objective The non-metabolised antihistamine fexofenadine has oral absorption resulting from transporter activity. Uptake by enterocyte organic anion transporting polypeptides and efflux by an ATP-binding cassette transporter (P-glycoprotein) are primary ...
Marc L Chretien, David G Bailey, Linda Asher, Jeremy Parfitt, David Driman, Jamie Gregor, George K Dresser   +6 more
doaj   +1 more source

Suppression of wheal and flare in histamine test by the main H1 antihistamines commercialized in Brazil [PDF]

Anais Brasileiros de Dermatologia, 2018
: Background: Several dermatoses are mediated by histamine, such as urticaria, angioedema, and papular urticaria. There are no Brazilian studies comparing the potency of antihistamines.
Helena Maciel-Guerra, Mariana Álvares Penha, Marília Formentini Scotton Jorge, Ricardo da Silva Libório, Ana Cláudia Nazareno dos Anjos Carrijo, Maria Rita Parise-Fortes, Hélio Amante Miot   +6 more
doaj   +2 more sources

Safety of fexofenadine and other second-generation oral antihistamines before and after the removal of the prescription requirement in Italy and other European countries: A real-world evidence study and systematic review

World Allergy Organization Journal, 2022
Background: The change from prescription to over-the-counter (OTC) status of oral antihistamines may raise concerns about drug safety due to the possibility of misuse/abuse.
Carla Carnovale, PharmD, Vera Battini, PharmD, Michele Gringeri, PharmD, Marina Volonté, DVM, Maria Chiara Uboldi, PharmD, PhD, Andrea Chiarenza, MD, PhD, Giovanni Passalacqua, MD   +6 more
doaj   +1 more source

Effect of fexofenadine on the quality of life of Japanese cedar pollinosis patients

Allergology International, 2004
Background: The aim of the present survey was to investigate the changes associated with fexofenadine administration in the quality of life (QOL) of Japanese cedar pollinosis patients.
Kimihiro Okubo, Minoru Gotoh, Kenichi Shimada, Masayo Ritsu, Makoto Kobayashi, Minoru Okuda   +5 more
doaj   +1 more source

Altered Expression of Long Non-Coding RNAs NEAT1, H19, and MALAT1 in Peripheral Blood ‎Cells of Patients with Allergic Rhinitis after Treatment with Pharmaceutical Combinations of ‎ Budesonide and Fexofenadine versus Fluticasone Propionate and Fexofenadine

مجله علمی دانشگاه علوم پزشکی کردستان, 2023
Background and Aim: Allergic rhinitis is the most common chronic inflammatory disorder of the nasal mucosa. Long non-coding RNAs (lncRNA) are a group of non-coding RNAs involved in the pathogenesis of various inflammatory diseases. This study intended to
Gelayol Asadi, Sara Falahi, Misagh Rajabinejad, Parisa Feizollahi, Seyyed Hamidreza Mortazavi, Ali Gorgin Karaji, Farhad Salari, Alireza Rezaiemanesh   +7 more
doaj