Results 21 to 30 of about 5,039 (204)
Changed expression of placental transporters and disrupted epigenetic patterns in a rat model of schizophrenia [PDF]
Frontiers in PharmacologyIntroductionGenerally, the pregnant women with schizophrenia have higher consumption of medicinal drugs. During pregnancy, placental ABC transporters regulate drug disposition and are involved in fetal and placental development.
Péter Szatmári +5 more
doaj +2 more sources
Fexofenadine Brain Exposure and the Influence of Blood-Brain Barrier P-Glycoprotein After Fexofenadine and Terfenadine Administration [PDF]
, 2009 P-glycoprotein (P-gp) plays an important role in determining net brain uptake of fexofenadine. Initial in vivo experiments with 24-h subcutaneous osmotic minipump administration demonstrated that fexofenadine brain penetration was 48-fold higher in mdr1a(
Bridges, A. S. +4 more
core +1 more source
BMC Pharmacology and Toxicology, 2019 Background As a new generation antihistamine, fexofenadine has been widely used in allergic diseases. However, there is still a lack of collective evidence regarding the antihistamine effects and safety profiles of fexofenadine relative to other ...
Cheng-zhi Huang +4 more
doaj +1 more source
From Anaphylaxis to Arrhythmia: A Case Report of Fexofenadine induced Bradyarrhythmia [PDF]
Journal of Clinical and Diagnostic ResearchAnaphylaxis is a rapid, potentially fatal systemic hypersensitivity reaction, with adrenaline recommended as first-line treatment, followed by beta-2-agonists, glucocorticoids, and antihistamines.
S Subha Sree +2 more
doaj +1 more source
Pharmaceutics, 2020 Drug absorption from the gastrointestinal tract (GIT) is one of the major problems affecting the bioavailability of orally absorbed drugs. This work aims to enhance Fexofenadine HCl oral bioavailability in vivo, the drug used for allergic rhinitis.
Ali M. Nasr +5 more
doaj +1 more source
BMC Chemistry, 2022 Fexofenadine hydrochloride and pseudoephedrine hydrochloride are prescribed in a combined dosage form for the treatment of allergic rhinitis. In the present work, a sensitive synchronous fluorescence spectroscopic method was applied in conjunction with ...
Sherif Ramzy +2 more
doaj +1 more source
Association between Fexofenadine Use during Pregnancy and Fetal Outcomes
, 2020 Importance: Fexofenadine hydrochloride is a frequently used drug for treatment of allergic conditions during pregnancy, but the fetal safety of fexofenadine use has not been well studied.
Andersson, Niklas Worm +2 more
core +1 more source
Old versus new antihistamines: Effects on cognition and psychomotor functions
Journal of Family Medicine and Primary Care, 2022 Context: Antihistamines (AHs) are the most widely long-term therapeutic option to manage allergic diseases. This research aimed to study the effects of long-term administration of AHs: on cognitive (memory, mood, attention, sleep and executive function ...
K Sheth Shamil +4 more
doaj +1 more source
Allergology International, 2006 Background: Epinastine hydrochloride and fexofenadine hydrochloride, the second-generation antihistamines, are largely used in the indication of allergic rhinitis in Japan.
Kimihiro Okubo, Minoru Gotoh
doaj +1 more source
Effect of Rumex Acetosa Extract, a Herbal Drug, on the Absorption of Fexofenadine
Pharmaceutics, 2020 Herbal drugs are widely used for the auxiliary treatment of diseases. The pharmacokinetics of a drug may be altered when it is coadministered with herbal drugs that can affect drug absorption.
Jung Hwan Ahn +5 more
doaj +1 more source