Results 31 to 40 of about 5,039 (204)
Effect of fexofenadine hydrochloride on allergic rhinitis aggravated by air pollutants
ERJ Open Research, 2021 In recent decades, seasonal allergic rhinitis (SAR) prevalence has increased and recent studies have shown that air pollutants, such as diesel exhaust particles (DEP), can increase inflammatory and allergic biomarkers.
Anne K. Ellis +4 more
doaj +1 more source
Applications of human microdosing with accelerator mass spectrometry: assessment of ability to predict drug-drug interactions and determine the pharmacokinetics of enantiomers [PDF]
, 2012 In this thesis, new applications of microdosing were explored in two clinical trials. Methods were developed for the separation and quantification of 14C-labelled analytes in human plasma using two-dimensional HPLC and accelerator mass ...
Croft, M L
core +4 more sources
BMC Chemistry, 2020 This paper introduces the first electrochemical approach for the determination of Fexofenadine hydrochloride and Montelukast sodium as a combined form by constructing three new graphite electrodes coated with a polymeric membrane. The first electrode was
Dania Nashed +2 more
doaj +1 more source
National Journal of Physiology, Pharmacy and Pharmacology, 2017 Background: The second-generation antihistaminic fexofenadine has been claimed to be superior to terfenadine and cetirizine, in possessing the negligible sedating property and can be safely given to pilots and drivers.
Suresha K R, Suryanarayana R Babushaw
doaj +1 more source
Update meta-analysis on the efficacy and safety issues of fexofenadine
World Allergy Organization Journal, 2023 Background: Fexofenadine emerged as one of the most representative second generation histamine H1 antagonist drugs since the 1990s, with an outstanding efficacy and appreciable safety for the treatment of allergic patients.
René Maximiliano Gómez, MD, PhD +4 more
doaj +1 more source
Fexofenadine Protects Against Intervertebral Disc Degeneration Through TNF Signaling
Frontiers in Cell and Developmental Biology, 2021 Objective: Fexofenadine (FFD) is an antihistamine drug with an anti-inflammatory effect. The intervertebral disc (IVD) degeneration process is involved in inflammation in which tumor necrosis factor-α (TNF-α) plays an important role.
Kaiwen Liu +10 more
doaj +1 more source
Stimulating effects of the antihistamine fexofenadine: testing the dopamine transporter hypothesis
, 2006 Rationale: First- and second-generation antihistamines are known to produce different degrees of sedation. However, a few studies have shown that the H1-antagonist fexofenadine produces mild stimulating effects.
Ramaekers, J.G. +4 more
core +1 more source
FEXOFENADINE AND ORGANIC ANION TRANSPORTING POLYPEPTIDES (OATPs): TRANSPORT AND DRUG-DRUG INTERACTIONS [PDF]
, 2011 Transporters play a major role in the absorption and disposition of fexofenadine, suggesting this drug could be used as a probe of transporter activity.
Flynn, Colleen A.
core +1 more source
Medicine Advances, EarlyView.This narrative review examines the neurological adverse effects associated with commonly used H1‐antihistamines, focusing on how blood–brain barrier (BBB) penetration and patient age influence central nervous system (CNS) toxicity. The major finding is that first‐generation antihistamines, because of higher CNS penetration, are associated with ...
Syeda Samia Fatima +6 more
wiley +1 more source
Histamine 1 Receptor Blockade Enhances Eosinophil-Mediated Clearance of Adult Filarial Worms. [PDF]
PLoS Neglected Tropical Diseases, 2015 Filariae are tissue-invasive nematodes that cause diseases such as elephantiasis and river blindness. The goal of this study was to characterize the role of histamine during Litomosoides sigmodontis infection of BALB/c mice, a murine model of filariasis.
Ellen Mueller Fox +3 more
doaj +1 more source