Results 1 to 10 of about 59,586 (323)
FFAS Server: Novel Features and Applications. [PDF]
Nucleic Acids Research, 2011 The Fold and Function Assignment System (FFAS) server [Jaroszewski et al. (2005) FFAS03: a server for profile–profile sequence alignments. Nucleic Acids Research, 33, W284–W288] implements the algorithm for protein profile–profile alignment introduced ...
Adam Godzik +2 more
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Intervention by Picroside II on FFAs Induced Lipid Accumulation and Lipotoxicity in HepG2 Cells
Journal of Ayurveda and Integrative Medicine, 2021 Background: Accumulation of free fatty acids (FFAs) in hepatocytes is a hallmark of liver dysfunction and non-alcoholic fatty liver disease (NAFLD).
Hiteshi Dhami-Shah +2 more
exaly +5 more sources
Lipids in Health and Disease, 2020 Background Han and Uygur are the two main nationalities living in Xinjiang, China. There are significant differences in the incidence of metabolic diseases for two nationalities, but the specific reasons are not clear. Obesity is an important risk factor
Zhang Jun, Jianxin Xie, Cuizhe Wang
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The Association Between Higher FFAs and High Residual Platelet Reactivity Among CAD Patients Receiving Clopidogrel Therapy [PDF]
Frontiers in Cardiovascular Medicine, 2023 BackgroundMetabolic abnormalities are associated with the occurrence, severity, and poor prognosis of coronary artery disease (CAD), some of which affect the antiplatelet efficacy of clopidogrel.
Kangning Han, Meishi Ma, Shutong Dong
exaly +4 more sources
Lipopolysaccharide induced mouse depression model can better simulate changes in peripheral blood FFAs in alMDD. [PDF]
PLoS ONENumerous studies have highlighted a strong association between free fatty acids (FFAs) and major depressive disorder (MDD), however, the underlying mechanisms remain poorly understood.
Jincai Pan +8 more
doaj +5 more sources
Diabetes, Metabolic Syndrome and Obesity: Targets and TherapyYingda Fu,1 Guangbing Li,1,2 Zichen Feng,1 Jun Liu,2 Xiaoyu Wang,1 Tao Wang,2 Jun Liu1,2 1Department of Hepatobiliary Surgery and Center of Organ Transplantation, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan ...
Guangbing Li, Xiaoyu Wang, Yingda Fu
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Journal of Lipid Research, 2021 FFAs display pleiotropic functions in human diseases. Short-chain FAs (SCFAs), medium-chain FAs, and long-chain FAs are derived from different origins, and precise quantification of these FFAs is critical for revealing their roles in biological processes.
Juan Lei, Mingyue Zhou, Lei Wu
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A20 Attenuates FFAs-Induced Lipid Accumulation in Nonalcoholic Steatohepatitis
International Journal of Biological Sciences, 2015 A20 is a ubiquitin-editing enzyme that attenuates the activity of proximal signaling complexes at pro-inflammatory receptors. It has been well documented that A20 protein plays an important role in response to liver injury and hepatocytes apoptosis in ...
Zhiwei Chen, Qing Lin, Luoyan Ai
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Overexpression of endogenous galactolipases and an efflux transporter enhances the secretion of extracellular free fatty acids by Synechococcus elongatus PCC 7942 [PDF]
Biotechnology for Biofuels and BioproductsBackground Cyanobacterial mutants engineered for production of free fatty acids (FFAs) are potentially useful sources of biofuels, since the FFAs are secreted into the extracellular medium.
Kotoha Nishimoto +9 more
doaj +2 more sources
Serum free fatty acids and progression of coronary artery calcification: sex specific findings from a large U.S. cohort study [PDF]
BMC Cardiovascular DisordersBackground Studies evaluating the longitudinal relationship between plasma free fatty acids (FFAs) and subclinical atherosclerosis remain limited. We investigated the prospective association between serum FFA levels and the progression of coronary artery
Azra Ramezankhani +2 more
doaj +2 more sources