Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey +7 more
wiley +1 more source
Metabolic and Signaling Dysregulation in a Cellular Model of Hepatic Insulin Resistance. [PDF]
Zbeeb H +4 more
europepmc +1 more source
ABSTRACT Despite all efforts, obesity remains a major health concern worldwide, with continuously increasing rates, affecting approx. 14% of the total world population, being as high as 43% in some countries. As obesity is related to numerous comorbidities, including type 2 diabetes, cardiovascular diseases, and some types of cancer, the consequences ...
Farhad Vahid +22 more
wiley +1 more source
Lutein Attenuates Lipid Accumulation in Association with TFEB Nuclear Translocation and Autophagy-Lysosomal Responses in a Cellular Model of Hepatic Steatosis. [PDF]
Saud F +6 more
europepmc +1 more source
ABSTRACT To summarise the scientific evidence from systematic reviews on the differences between fixed functional appliances (FFA) with and without skeletal anchorage for the treatment of Class II malocclusion in growing patients. A systematic search on six major databases was performed.
Valentina Rutili +4 more
wiley +1 more source
Effects of Bound Polyphenols on Lipid Metabolism in HepG2 Cells and Glucose-Induced <i>C. elegans</i> Models. [PDF]
Ghani I, Qiao Q, Li S, Liu Y, Li Z.
europepmc +1 more source
ABSTRACT Objective To assess the impact of baseline malocclusion severity on the number of prescribed, used aligners and treatment duration. Materials and Methods An unrestricted, independent search was conducted on the Invisalign ClinCheck database of a private practice for patients without any missing anterior teeth and whose treatment was finished ...
Angeliki Anna Gkinosati +5 more
wiley +1 more source
Lipid droplets and viruses: a dynamic battlefield of cellular resources. [PDF]
Ling X +5 more
europepmc +1 more source
Circular inference in visual cortical hierarchies in schizophrenia
Aim In schizophrenia, disrupted perceptual processes contribute to positive symptoms. However, it remains unclear how top‐down priors and bottom‐up likelihoods are represented across the hierarchy of visual cortices. To identify these processes within cortical hierarchies, the circular inference model offers a framework to account for the biased ...
Shuhei Hara +7 more
wiley +1 more source
Correlations between free fatty acids and volatile compounds in four pork cuts from Shanxia long black pigs: implications for cut-specific flavor generation. [PDF]
Zhang L, Luo W, Zhang Z, Li L, Huang Y.
europepmc +1 more source

