Results 191 to 200 of about 21,059 (297)

Angiopoietin‐like protein 3 complete and partial deficiency markedly accelerates apolipoprotein B48 and B100 metabolism in triglyceride‐rich lipoproteins in humans

Journal of Internal Medicine, EarlyView.
Abstract Background Angiopoietin‐like protein 3 (ANGPTL3) is a key circulating regulator of triglyceride metabolism and a promising pharmacological target. The physiological consequences of profound ANGPTL3 deficiency can be explored in individuals with inherited loss‐of‐function (LOF) variants, who show reduced lifetime risk of atherosclerotic ...
Marcello Arca, Elias Björnson, Laura D'Erasmo, Alessia Di Costanzo, Simone Bini, Ilenia Minicocci, Daniele Tramontano, Stella Covino, Giuseppe Ciarlo, Manuela Lombardi, Sanni Söderlund, Niina Matikainen, Linda Andersson, Martin Adiels, Marja‐Riitta Taskinen, Chris J. Packard, Jan Borén   +16 more
wiley   +1 more source

Intermittent hypoxia increases lipid insulin resistance in healthy humans: A randomized crossover trial

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
This scheme illustrates the main results of the present study showing an increase in circulating free fatty acids (FFA) that are likely to be related to several mechanisms like decrease in FFA insulin sensitivity and increase in FFA production. Significant changes are labelled in white, and non‐significant or hypothesis are labelled in pale green ...
Anne Briançon‐Marjollet, Marie Netchitaïlo, Fanny Fabre, Elise Belaidi, Claire Arnaud, Anne‐Laure Borel, Patrick Levy, Jean‐Louis Pépin, Renaud Tamisier   +8 more
wiley   +1 more source

High-pressure processing reshapes early lipid mobilization in <i>Camellia oleifera</i> seeds during a hot-humid postharvest window. [PDF]

Front Plant Sci
Wu J, Tang X, Yang S, Guan J, Li G, Qiu M.   +5 more
europepmc   +1 more source

Adaptation in FFA: Face or person?

Journal of Vision, 2010
X. Xu, X. Yue, I. Biederman, J. Kim, M. Lescroart   +4 more
openaire   +1 more source

Toll Like Receptor 4: A Potential Link Between Obesity and Metabolic Diseases

Obesity Reviews, EarlyView.
ABSTRACT Epidemiological evidence shows that obesity increases the risk of developing metabolic diseases. Nevertheless, the mechanisms behind this connection remain underappreciated. The substantial impact of these disorders on global health has led to extensive research efforts aimed at identifying the pathophysiological links between them.
Ghadeer Alhamar, Joanna Razafiarison, Fawaz Alzaid, Fahd Al‐Mulla, Rasheed Ahmad   +4 more
wiley   +1 more source

Modeling pathogenesis and progression of metabolic dysfunction-associated steatotic liver disease and therapeutic drug screening using hESC-derived mature polarized hepatocyte organoids. [PDF]

Stem Cell Res Ther
Qin C, Wu H, Liao P, Yan W, Shi X, Xie J, Liu S, Chen S, Cao X, Zhou Y, Duan Y.   +10 more
europepmc   +1 more source

GCMS Determination of Free Fatty Acids in the Presence of Triglycerides

The goal of the study was to investigate the kinetics of the esterification reactions of triacylglycerides (TAGs) and free fatty acids (FFAs). TAGs and FFAs are lipids that are produced in biological systems and have high production rates in several ...
Young, Luke
core  

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

Obesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey, Irene Pomares‐Bri, Paula de Juan‐Maciá, Mariló Olivares‐Vicente, Enrique Barrajón‐Catalán, Vicente Micol, Enrique Roche, María Herranz‐López   +7 more
wiley   +1 more source

Albumin orchestrates a natural host defence mechanism against mucormycosis. [PDF]

Nature
Pikoulas A, Morianos I, Nidris V, Hamdy R, Intze E, López-López Á, Moran-Garrido M, Muthu V, Halabalaki M, Papaioanou V, Papadovasilaki M, Kyrmizi I, Gu Y, Camunas-Alberca SM, Aerts R, Mercier T, Vanbiervliet Y, Cho SY, Spallone A, Jiang Y, Samonakis D, Kastritis E, Lax C, Tzardi M, Eliopoulos A, Georgila K, Carvalho A, Kurzai O, Rudramurthy SM, Elie C, Lanternier F, Petratos K, Garre V, Drakos E, Maertens J, Bruno VM, Kontoyiannis DP, Barbas C, Soliman SSM, Ibrahim AS, Chamilos G.   +40 more
europepmc   +1 more source

Effects Produced by Fixed Functional Appliances With and Without Skeletal Anchorage for the Treatment of Class II Malocclusion in the Growing Patient: A Review of Systematic Reviews

Orthodontics &Craniofacial Research, EarlyView.
ABSTRACT To summarise the scientific evidence from systematic reviews on the differences between fixed functional appliances (FFA) with and without skeletal anchorage for the treatment of Class II malocclusion in growing patients. A systematic search on six major databases was performed.
Valentina Rutili, Michele Nieri, Veronica Giuntini, Ersilia Vaccari, Lorenzo Franchi   +4 more
wiley   +1 more source