Results 171 to 180 of about 59,586 (323)

Five‐Year Treatment Outcomes of Macular Oedema Secondary to Central Retinal Vein Occlusion in Routine Clinical Practice: The Fight Retinal Blindness! Registry

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To report 5‐year outcomes in a cohort of patients who received anti‐VEGF therapy for macular oedema secondary to central retinal vein occlusion (CRVO) in routine clinical practice. Methods In this retrospective observational study, 593 treatment‐naïve eyes that commenced anti‐VEGF treatment between 1 January 2010, and 2019 were ...
Katrin Rudolph, Marianna Rosso, Mark Gillies, Adrian Hunt, Louise O'Toole, Alessandro Invernizzi, David Squirrell, Hemal Mehta, Richard Barry, Pierre‐Henry Gabrielle, Daniel Barthelmes   +10 more
wiley   +1 more source

Evaluation of the Safety and Therapeutic Range of Nanosecond Laser Treatment in Rabbits

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background Subthreshold, nanosecond laser therapy has potential as a treatment for age‐related macular degeneration; however, the therapeutic range and safety profile have not been fully documented. In this study, rabbits were used for a preclinical assessment of nanosecond laser treatment.
Glyn Chidlow, John P. M. Wood, Weng Onn Chan, Robert J. Casson   +3 more
wiley   +1 more source

PLIN5 Protects Against Ang II‐Induced Podocyte Lipotoxicity by Interacting With FKBP8 and Preserving Lipid Droplet–Mitochondria Contact

Cell Proliferation, EarlyView.
PLIN5‐FKBP8 tethers lipid droplets to mitochondria to counteract Ang II‐induced lipotoxicity. ABSTRACT Chronic kidney disease (CKD) remains a major global health challenge. Angiotensin II (Ang II)‐induced lipotoxicity is an important contributor to podocyte injury.
Ping Wang, Wenjie Chen, Jingjing Ke, Hongtu Hu, Zhuan Peng, Yue Qi, Guohua Ding, Jijia Hu   +7 more
wiley   +1 more source

Free Fatty Acids Carried by Lipoproteins: Revisiting the Overlooked Cargo. [PDF]

Acta Physiol (Oxf)
Henderson GC, Buhman KK, Tomoo K.
europepmc   +1 more source

In vivo differentiation of scarring alopecia using line‐field confocal optical coherence tomography: a pilot study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives: Diagnosing cicatricial alopecia is challenging. Even with histology, a definitive diagnosis cannot always be made. Line‐field confocal optical coherence tomography (LC‐OCT), a non‐invasive imaging method with high resolution used in vivo, has proven helpful in diagnosing scarring alopecia.
Marie‐Christine Nutz, Julia Welzel, Daniela Hartmann, Lars E. French, Maximilian Deußing, Elke C. Sattler   +5 more
wiley   +1 more source

Serum Free Fatty Acid-Based Diagnostic Index for Cervical Cancer Including High-Risk HPV-Negative Cases: An Independent Validation Study. [PDF]

Diagnostics (Basel)
Katoh Y, Fujii Y, Yamazaki N, Kubo A, Kamata S, Okuma Y, Yang T, Futatsugi A, Sakamoto M, Hino H, Ogawa T, Fukuta M, Iwata T, Nishio H, Sugawara M, Kawana K, Hirai S.   +16 more
europepmc   +1 more source

Rethinking diabetic retinopathy: Homeostatic mechanisms for retinal clearance

Diabetic Medicine, EarlyView.
In the healthy retina, balanced production and clearance of metabolic waste and fluid maintain retinal homeostasis and normal visual function. Diabetes disrupts this balance, increasing the accumulation of metabolic waste products, including advanced glycation end products (AGEs) and advanced lipoxidation end products (ALEs), while impairing waste and ...
Karis Little, Judith Lechner, Giulia De Rossi, Tara Cullen, Jennifer Perais, Eleni Beli, Noemi Lois, Alan W. Stitt   +7 more
wiley   +1 more source

Vitamin E treatment modulates steatotic and attenuates oxidative stress in a MASLD in vitro model. [PDF]

Mol Biol Rep
Teymoorian SK, Nouri K, Choshali MA, Hassan M, Rismani E, Vosough M, Piryaei A.   +6 more
europepmc   +1 more source

The Impact of Immunoglobulins on Cardiovascular Diseases and Lipid Profiles in Elderly and Middle-Aged Chinese Individuals: A 15-Year Retrospective Study. [PDF]

J Clin Lab Anal
In a 15‐year retrospective study of Chinese adults over 45, we explored the links between immunoglobulins, CVDs, and lipid profiles. Temporal increases in IgG and IgA were positively associated with FFAs, offering new insights into humoral immunity and lipid metabolism, suggesting a mechanistic link between humoral immunity and dyslipidemia ...
Li Y, Jiao L, Gao Y, Ni XF.
europepmc   +2 more sources

Adrenal hormones in the maintenance of glucose homeostasis during prolonged fasting in male glucagon‐deficient mice

Journal of Diabetes Investigation, EarlyView.
Compensatory corticosterone‐mediated lipolysis and hepatic gluconeogenesis (via amino acids and glycerol) prevent hypoglycemia in GCGKO mice during prolonged fasting. ABSTRACT Aims/Introduction Glucagon is a key regulator of fasting glucose homeostasis, but the contribution of adrenal hormones during prolonged fasting remains unclear.
Sayumi Kanie, Koki Nishida, Yusuke Seino, Shihomi Hidaka, Shinji Ueno, Hiroaki Sumioki, Eisuke Tomatsu, Takuya Haraguchi, Naoya Murao, Haruki Fujisawa, Takeshi Takayanagi, Yoshihisa Sugimura, Yoshitaka Hayashi, Atsushi Suzuki   +13 more
wiley   +1 more source