Results 151 to 160 of about 59,586 (323)

In planta analysis of the mode of action of cinmethylin and confirmation of fatty acyl‐ACP thioesterases (FATs) as primary site of action

Pest Management Science, EarlyView.
In planta analysis of the mode of action of cinmethylin and confirmation of fatty acyl‐ACP thioesterases (FATs) as primary site of action. Cinmethylin inhibits FATs, disrupting eukaryotic de novo lipid biosynthesis and causing defects in cell division, elongation and integrity. We confirm FATs as the primary site of action in planta.
Maximillian Pollmeier, Aisha Gerhardt, Janneke Hendriks, Katharina Kaprocki, Alexandra Zimmermann, Sarina Ruehm, Martina Marnet, Maria Stroe, Jorge Alfredo Rojas Biava, Clara Hofmann, Michael Betz, Sascha Schlaefer, Philipp Ternes, Jens Lerchl, Selene Garcia‐Hernandez, Philipp Johnen   +15 more
wiley   +1 more source

Evolutionary origins of the multienzyme architecture of giant fungal Fatty Acid synthase

, 2014
Fungal fatty acid synthase (fFAS) is a key paradigm for the evolution of complex multienzymes. Its 48 functional domains are embedded in a matrix of scaffolding elements, which comprises almost 50% of the total sequence and determines the emergent ...
Maier, Timm, Jakob, Roman P., Bukhari, Habib S. T., Maier, Timm (author), Jakob RP, Jakob, Roman P. (author), Bukhari HST, Bukhari, Habib S.T. (author), Maier T   +8 more
core   +1 more source

Liquiritigenin Ameliorates High‐Fat Diet‐Induced Hepatic Steatosis by Promoting Lipid Droplet Catabolism via PLIN2‐ATGL Regulation

Phytotherapy Research, EarlyView.
Liquiritigenin promotes expression of CGI‐58 and enhances lipolysis by down‐regulating expression of PLIN2, thereby facilitating the catabolism of larger‐sized lipid droplets and producing smaller‐sized lipid droplets, resulting in enhanced activity of lipophagy and ameliorated hepatic steatosis. ABSTRACT Metabolic‐associated fatty liver disease (MAFLD)
Zhuoya Xu, Jingmiao Chen, Hong Qin, Yansong Fu, Cunqi Lv, Zhipeng Wang, Xi Liu, Wenya Zheng   +7 more
wiley   +1 more source

The impact of the administration of red ginseng (Panax ginseng) on lipid metabolism and free fatty acid profiles in healthy horses using a molecular networking approach

Frontiers in Veterinary Science
This study investigated the potential benefits of the administration of red ginseng (RG) on lipid metabolism and the profiles of individual free fatty acids (FFAs) in healthy horses.
Young Beom Kwak, Hye Hyun Yoo, Jungho Yoon   +2 more
doaj   +1 more source

Texas FFA Entomology materials

These are the slides used during the spring 2025 webinar series for the Texas FFA Entomology training offered by the Invertebrate Zoology Collection of the Natural Science Research Laboratory, Museum of Texas Tech University and the Entomology Lab of the Texas Tech Department of Plant & Soil Sciences. The content of thse presentations emphasizes topics
Prescott, Lillian, Forrest, Jill, Girón Duque, Jennifer C.   +2 more
openaire   +2 more sources

Suppression of PKM2 by Leonurine Attenuates Alcoholic Hepatitis Through Regulating Glycolytic Reprogramming

Phytotherapy Research, EarlyView.
Leonurine inhibits PKM2 to remodel hepatocyte glycolysis, thereby alleviating liver injury in alcoholic hepatitis. ABSTRACT Alcoholic hepatitis (AH) is a liver disease caused by long‐term heavy drinking. In the early stages, it usually manifests as fatty liver, which can then develop into liver fibrosis and cirrhosis.
Xuan‐Xuan Zhang, Gao‐Feng Pan, Hong Fang, Xiao‐Peng Liu, Jing Sun, Ji‐Xiang Chen, Xin Fan, Jia‐Hao Feng   +7 more
wiley   +1 more source

Notoginsenoside R2 Antagonizes Renal Interstitial Fibrosis by Regulating Fatty Acid Oxidation via the CASP2/ALDH3A1 Axis

Phytotherapy Research, EarlyView.
Proposed mechanism by which notoginsenoside R2 (NGR2) attenuates renal interstitial fibrosis. In injured renal tubular epithelial cells, CASP2 downregulation and enhanced ubiquitin‐dependent degradation of ALDH3A1 disrupt mitochondria‐associated endoplasmic reticulum membranes (MAMs) and impair fatty acid oxidation (FAO), leading to lipid accumulation ...
Guanting Chen, Tao Li, Zhenzhen Wang, Hao Zhao, Xiaoxia Xun, Yijiao Wang, Shiyuan Jiang, Qing Zhang, Weiwei Sun, Kang Yang, Yaoxian Wang   +10 more
wiley   +1 more source

A mediation analysis of the role of total free fatty acids on pertinence of gut microbiota composition and cognitive function in late life depression

Lipids in Health and Disease
Background Extensive evidence demonstrates correlations among gut microbiota, lipid metabolism and cognitive function. However, there is still a lack of researches in the field of late-life depression (LLD).
Yan Chen, Jiarong Li, Dansheng Le, Yuhan Zhang, Zhengluan Liao   +4 more
doaj   +1 more source

Structure and concentartion of differenty fatty acid (FFAS) affect steatosis extent and apoptosis in hepatocytes coltures

, 2006
Steatosis can be induced in hepatocytes coltures . FFAs strucutre , concentration and cell line type, arei mportant factors in modulating extent of TG storage and apoptosis. Oleic acid is more steatogenic but less toxic than palmitic and when associted
LORIA, Paola, Lonardo A, Bormioli ML, Ricchi M, ANZIVINO, Claudia, CARULLI, Lucia, CARULLI, Nicola, Odoardi MR, BERTOLOTTI, Marco   +8 more
core  

Ajugol Improves Liver Fibrosis by Modulating Bile Acid and Arachidonic Acid Metabolism in Mice

Phytotherapy Research, EarlyView.
Ajujol ameliorates hepatic fibrosis by regulating bile acid metabolism and suppressing inflammatory responses. ABSTRACT Ajugol (AJ), the primary component extracted from the root of Rehmannia glutinosa, exhibits protective effects against metabolic dysregulation and chronic inflammation.
Xia Wei, Fangyuan Wang, Dingqi Zhang, Longhui Zhang, Feipeng Xu, Gaofeng Chen, Hua Zhang, Ping Liu, Wei Liu, Ying Xu   +9 more
wiley   +1 more source