Results 161 to 170 of about 21,059 (297)

Targeting Egfr‐Mediated Cell Proliferation and Lipid Metabolism Separation Effectively Accelerate Liver Regeneration

Cell Proliferation, EarlyView.
AREG coordinates cell proliferation and lipid metabolism reprogramming during liver regeneration and targeting lipid metabolism can promote liver regeneration. ABSTRACT Hepatocyte proliferation restores liver mass after partial hepatectomy (PHx), but the metabolic cost of this process remains unclear.
Yuelei Hu, Shifei Song, Ruilin Wang, Ni An, Jinmei Diao, Yuguo Chen, Juan Liu, Guoyue Lv   +7 more
wiley   +1 more source

Desorption Electrospray Ionization-Mass Spectrometry Imaging Provides Spatiochemical Information on Potential Biocontrol Agents against <i>Phytophthora capsici</i> Infection in Tomato Plants. [PDF]

J Am Soc Mass Spectrom
Robinson JY, Shepard HS, Ambachew D, Eyegheleme PJ, May JC, Mmbaga MT, McLean JA.   +6 more
europepmc   +1 more source

Comprehensive quantification of C4 to C26 free fatty acids using a supercritical fluid chromatography-mass spectrometry method in pharmaceutical-grade egg yolk powders intended for total parenteral nutrition use

Free fatty acids (FFAs) are important energy sources and significant for energy transport in the body. They also play a crucial role in cellular oxidative stress responses, following cell membrane depolarization, making accurate quantification of FFAs ...
Retrato, Mark Dennis Chico, Ubhayasekera, S. J. Kumari A.,, Nguyen, Anh Vu, Retrato, Mark Dennis Chico,, Ubhayasekera, S. J. Kumari A., Bergquist, Jonas, Nguyen, Anh Vu,, Bergquist, Jonas,   +7 more
core   +1 more source

SCD2 Alleviates Diabetes‐Associated Cognitive Dysfunction by Improving Microglial Lipid Metabolism

Cell Proliferation, EarlyView.
This study reveals a novel mechanism of microglial metabolic dysfunction in diabetic cognitive impairment. Defective SCD2 disrupts monounsaturated fatty acid (MUFA) metabolism, triggering mitochondrial oxidative phosphorylation dysfunction and leading to abnormal lipid droplet accumulation (marked by PLIN2).
Yang Yang, Juan He, Jing Zheng, Bing Shao, Lixin Shi, Miao Zhang   +5 more
wiley   +1 more source

Mechanistic insights into how intrapancreatic fat deposition drives the development of acute pancreatitis. [PDF]

Int J Biol Sci
Gu X, Zhang H, Lin W, Chen W, Le C, Huang Z, Liu Q, Yang J.   +7 more
europepmc   +1 more source

Zeb2 Controls Retinal Physiological and Pathological Angiogenesis by Regulating Astrocyte Proliferation and Differentiation

Cell Proliferation, EarlyView.
During development, the oxygen‐sensitive transcription factor Zeb2 restrains astrocyte proliferation and maturation to ensure balanced retinal angiogenesis. In disease, it promotes the neurotoxic A1 astrocyte phenotype and inflammation, thereby promoting reparative revascularization over pathological neovascularization.
Jing Liu, Yanan Guo, Kangjian Xiang, Shuyi Wang, Dongchang Xiao, Mengqing Xiang   +5 more
wiley   +1 more source

Hepatocyte Models for Metabolic Dysfunction-Associated Steatotic Liver Disease: A Comparative Analysis of Non-HepG2 Cell Models. [PDF]

Int J Mol Sci
Kotlyarova A, Kotlyarov S.
europepmc   +1 more source

Sharp estimation in sup norm with random design

In this paper, we study the estimation of a function based on noisy inhomogeneous data (the amount of data can vary on the estimation domain). We consider the model of regression with random design, where the design density is unknown.
GaI¨ffas, Stéphane
core  

In vivo differentiation of scarring alopecia using line‐field confocal optical coherence tomography: a pilot study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives: Diagnosing cicatricial alopecia is challenging. Even with histology, a definitive diagnosis cannot always be made. Line‐field confocal optical coherence tomography (LC‐OCT), a non‐invasive imaging method with high resolution used in vivo, has proven helpful in diagnosing scarring alopecia.
Marie‐Christine Nutz, Julia Welzel, Daniela Hartmann, Lars E. French, Maximilian Deußing, Elke C. Sattler   +5 more
wiley   +1 more source

SIRT3-mediated mitochondrial fatty acid oxidation protects against hepatic lipid deposition in fatty liver hemorrhagic syndrome. [PDF]

Poult Sci
Cao P, Chen J, Zeng C, Hu Y, Yuan J, Guo X, Cao H, Zhang C, Zhuang Y, Hu G.   +9 more
europepmc   +1 more source