Results 21 to 30 of about 236,033 (259)

Randomly Coupled 19-Core Multi-Core Fiber with Standard Cladding Diameter

, 2023
We developed a randomly-coupled 19-core fiber with standard 125-μm cladding diameter with spatial mode dispersion of 10.8ps/√km, enabling a data rate of 1.7 Pb/s, the highest reported amongst optical fibers with standard cladding ...
Hayashi T., Rademacher G., Luis R. S., Furukawa H., Di Sciullo G., Okonkwo C., Ross-Adams A., Withford M. J., Puttnam B. J., Nagashima T., Antonelli C., Gross S., Van Den Hout M., Sakaguchi J., Inoue A.   +14 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Yb-doped Large Pitch Fiber with 105 µm mode field diameter

, 2022
S.1871-1873We present an active Yb-doped Large Pitch Fiber design with 105 m mode field diameter. The fiber was tested in a fiber CPA system delivering sub 500 fs, 2 mJ pulses with 3.8 GW peak power.
Jansen, F., Stutzki, F., Rothhardt, J., Hädrich, S., Carstens, H., Tünnermann, A., Eidam, T., Jauregui, C., Limpert, J.   +8 more
core  

Biocompatible diameter-oscillating fiber with microlens endface

Optics Express, 2021
Optical fibers have been widely applied to life science, such as laser delivering, fluorescence collection, biosensing, bioimaging, etc. To resolve the challenges of advanced multiphoton biophotonic applications utilizing ultrashort laser pulses, here we report a flexible diameter-oscillating fiber (DOF) with microlens endface fabricated by using ...
Jingyang, Lian, Bin, He, Wenlong, Wang, Yuankai, Guo, Yue, Xu, Xiaoming, Wei, Zhongmin, Yang   +6 more
openaire   +2 more sources

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

26-mJ pulse energy Q-switched large-pitch fiber laser system with excellent beam quality

, 2022
Paper 82371SIn this work we report on what we believe is the highest pulse energy obtained from an effectively single-mode Qswitched fiber laser system to date. This result has been obtained using rare-earth-doped double-clad large-pitch fibers which are
Stutzki, Fabian, Limpert, Jens, Jansen, Florian, Tünnermann, Andreas, Liem, Andreas, Jauregui, Cesar   +5 more
core   +1 more source

Effect of fiber diameter on flexural properties of fiber-reinforced composites

Indian Journal of Dental Research, 2013
Flexural strength (FS) is one of the most important properties of restorative dental materials which could be improved in fiber-reinforced composites (FRCs) by several methods including the incorporation of stronger reinforcing fibers.This study evaluates the influence of the glass fiber diameter on the FS and elastic modulus of FRCs at the same weight
Mohammad Bagher Rezvani, Mohammad Atai, Faeze Hamze   +2 more
openaire   +3 more sources

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source