Results 51 to 60 of about 109,242 (281)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Nonlinear spectral analysis of Peregrine solitons observed in optics and in hydrodynamic experiments [PDF]

, 2018
The data recorded in optical fiber [1] and in hydrodynamic [2] experiments reported the pioneering observation of nonlinear waves with spatiotemporal localization similar to the Peregrine soliton are examined by using nonlinear spectral analysis.
Chabchoub, Amin, El, Gennady, Kibler, Bertrand, Randoux, Stephane, Suret, Pierre   +4 more
core   +4 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Comprehensive Study of Entanglement Photon Source: Bulk Optics, Waveguides and Integrated Photonic Chip Hardware [PDF]

EPJ Web of Conferences
In quantum technology, entanglement is the key resource to perform experiments in quantum computing, quantum communication, quantum sensing and metrology.
H Sai Sidhartha, P Poonguzhali
doaj   +1 more source

Modal Noise Mitigation through Fiber Agitation for Fiber-fed Radial Velocity Spectrographs

, 2018
Optical fiber modal noise is a limiting factor for high precision spectroscopy signal-to-noise in the near-infrared and visible. Unabated, especially when using highly coherent light sources for wavelength calibration, modal noise can induce radial ...
Eggerman, Dominic, Fischer, Debra A., Jurgenson, Colby A., McCracken, Tyler M., Petersburg, Ryan R., Sawyer, David, Szymkowiak, Andrew E.   +6 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Generation and subwavelength focusing of longitudinal magnetic fields in a metallized fiber tip [PDF]

, 2014
We demonstrate experimentally and numerically that in fiber tips as they are used in NSOMs azimuthally polarized electrical fields (|E$_{\text{azi}}$|$^2$/|E$_{\text{tot}}$|$^2$ $\approx$ 55% $\pm $ 5% for 1.4\mu m tip aperture diameter and \lambda$_0$ =
Banzer, Peter, Kriesch, Arian, Peschel, Ulf, Pfeifer, Hannes, Ploss, Daniel   +4 more
core   +3 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

HERMITIAN SYMMETRY BASED FIBER NON-LINEARITY COMPENSATION IN OPTICAL OFDM NETWORKS

International Journal of Communication Networks and Security, 2013
Orthogonal Frequency Division Multiplexing (OFDM) is a modulation technique which is now used in most new and emerging broadband wired and wireless communication systems such as standard 802.11a/b/g/n, Digital Video Broad casting Television (DVB-TV), and Long Term Evolution (LTE) in the next mobile generation, due to its capacity in solving the ...
KAMALA KANNAN P, GURU VIGNESH B, INIYAN P A, ILAVARASAN T   +3 more
openaire   +1 more source

Linear and nonlinear optical properties of carbon nanotube-coated single-mode optical fiber gratings [PDF]

, 2011
This paper was published in OPTICS LETTERS and is made available as an electronic reprint with the permission of OSA. The paper can be found at the following URL on the OSA website: http://dx.doi.org/10.1364/OL.36.002104.
Benoit Simard, Chan, Choi, Chow, Chow, Chow, Claudio J. Oton, Guillermo E. Villanueva, Jacques Albert, Jakubinek, Joaquín Matres, Kingston, Li-Yang Shao, Michael B. Jakubinek, Pere Pérez-Millán, Sakakibara, Set, Vallaitis   +17 more
core   +2 more sources