Results 1 to 10 of about 55,993 (169)

Magnetic, Thermal, and Transport Properties of Co2Ti1.5Sn0.5 Heusler Alloy

open access: yesAlloys, 2022
In this work, the structural, magnetic, thermal, and transport properties of the arc-melted polycrystalline Heusler alloy Co2Ti1.5Sn0.5 are investigated. The alloy crystallizes in an L21 structure with a space group of Fm-3m.
Sunitha Raveendran Athul   +6 more
doaj   +1 more source

Comparison of Different Tissue Clearing Methods for Three-Dimensional Reconstruction of Human Brain Cellular Anatomy Using Advanced Imaging Techniques

open access: yesFrontiers in Neuroanatomy, 2021
The combination of tissue clearing techniques with advanced optical microscopy facilitates the achievement of three-dimensional (3D) reconstruction of macroscopic specimens at high resolution.
Marina Scardigli   +19 more
doaj   +1 more source

Dissecting Neuronal Activation on a Brain-Wide Scale With Immediate Early Genes

open access: yesFrontiers in Neuroscience, 2020
Visualizing neuronal activation on a brain-wide scale yet with cellular resolution is a fundamental technical challenge for neuroscience. This would enable analyzing how different neuronal circuits are disrupted in pathology and how they could be rescued
Alessandra Franceschini   +8 more
doaj   +1 more source

Tracking the Effect of Therapy With Single-Trial Based Classification After Stroke

open access: yesFrontiers in Systems Neuroscience, 2022
Stroke is a debilitating disease that leads, in the 50% of cases, to permanent motor or cognitive impairments. The effectiveness of therapies that promote recovery after stroke depends on indicators of the disease state that can measure the degree of ...
Alessandro Scaglione   +8 more
doaj   +1 more source

Fast Optical Investigation of Cardiac Electrophysiology by Parallel Detection in Multiwell Plates

open access: yesFrontiers in Physiology, 2021
Current techniques for fast characterization of cardiac electrophysiology employ optical technologies to control and monitor action potential features of single cells or cellular monolayers placed in multiwell plates.
Caterina Credi   +16 more
doaj   +1 more source

Quantification of Myocyte Disarray in Human Cardiac Tissue

open access: yesFrontiers in Physiology, 2021
Proper three-dimensional (3D)-cardiomyocyte orientation is important for an effective tension production in cardiac muscle. Cardiac diseases can cause severe remodeling processes in the heart, such as cellular misalignment, that can affect both the ...
Francesco Giardini   +16 more
doaj   +1 more source

Functional cardiac imaging by random access microscopy

open access: yesFrontiers in Physiology, 2014
Advances in the development of voltage sensitive dyes and Ca2+ sensors in combination with innovative microscopy techniques allowed researchers to perform functional measurements with an unprecedented spatial and temporal resolution.
Claudia eCrocini   +7 more
doaj   +1 more source

KHz-rate volumetric voltage imaging of the whole Zebrafish heart

open access: yesBiophysical Reports, 2022
Fast volumetric imaging is essential for understanding the function of excitable tissues such as those found in the brain and heart. Measuring cardiac voltage transients in tissue volumes is challenging, especially at the high spatial and temporal ...
Leonardo Sacconi   +6 more
doaj   +1 more source

APP and Bace1: Differential effect of cholesterol enrichment on processing and plasma membrane mobility

open access: yesiScience, 2023
Summary: High cholesterol levels are a risk factor for the development of Alzheimer’s disease. Experiments investigating the influence of cholesterol on the proteolytic processing of the amyloid precursor protein (APP) by the β-secretase Bace1 and on ...
Claudia Capitini   +10 more
doaj   +1 more source

Bessel Beam Illumination Reduces Random and Systematic Errors in Quantitative Functional Studies Using Light-Sheet Microscopy

open access: yesFrontiers in Cellular Neuroscience, 2018
Light-sheet microscopy (LSM), in combination with intrinsically transparent zebrafish larvae, is a method of choice to observe brain function with high frame rates at cellular resolution.
M. Caroline Müllenbroich   +14 more
doaj   +1 more source

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