Results 41 to 50 of about 12,574,839 (304)

Determination of non-linear refractive index of laser crystals and ceramics via different optical techniques

open access: yesOptical Materials: X, 2020
The exact knowledge of optical material parameters is crucial for laser systems design. Therefore, the work reported herein was dedicated to the determination of an important parameter that is typically not known or only known with insufficient precision:
Laurent Lamaignère   +10 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Classification and integration of four-dimensional dynamical systems admitting non-linear superposition

open access: yes, 2017
The method of integration of dynamical systems admitting non-linear superpositions is applied to four-dimensional non-linear dynamical systems. All four-dimensional dynamical systems admitting non-linear superpositions with four-dimensional Vessiot ...
Ibragimov, Nail,   +1 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Non-linear transformation optics

open access: yes, 2020
The concept of transformation optics is extended to non-linear media. It is shown that transformation optics can be generalized to include arbitrary non-linear response.
S A Tretyakov, L Bergamin
core  

NON-LINEAR OPTICAL WAVEGUIDING IN SEMICONDUCTORS

open access: yesLe Journal de Physique Colloques, 1988
Practical device implementations of non-linear waveguides may utilise the defocussing non-linearity associated with the fundamental absorption edge of semiconductors. A suitable slab waveguide structure would involve a non-linear guiding layer bounded by cladding layers which are non-absorbing and hence linear at the operating wavelength.
Lambkin, P., Shore, K.
openaire   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Image sharpening metrics and search strategies for indirect adaptive optics [PDF]

open access: yes, 2000
Adaptive optics is concerned with the correction of turbulence induced aberrations and mis-alignments in optical systems. It is an expensive and complicated technology which has been developed for astronomy and defence applications.
Doble, N., Doble, Nathan
core  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy