Results 61 to 70 of about 369,770 (296)

Estimation of heavy tails in optical non-linear processes

New Journal of Physics, 2021
In optical non-linear processes, rogue waves can be observed, which can be mathematically described by heavy-tailed distributions. These distributions are special since the probability of registering extremely high intensities is significantly higher ...
Éva Rácz, László Ruppert, Radim Filip   +2 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Two-photon all-optical neurophysiology for the dissection of larval zebrafish brain functional and effective connectivity

Communications Biology
One of the most audacious goals of modern neuroscience is unraveling the complex web of causal relations underlying the activity of neuronal populations on a whole-brain scale.
Lapo Turrini, Pietro Ricci, Michele Sorelli, Giuseppe de Vito, Marco Marchetti, Francesco Vanzi, Francesco Saverio Pavone   +6 more
doaj   +1 more source

Overcoming the thermal regime for the electric-field driven Mott transition in vanadium sesquioxide

Nature Communications, 2019
Thermal effects limit the speed of the electrically driven insulator-metal transition in V2O3 to tens of picoseconds. Here the authors show that under an intense THz-electric-field excitation the thermal regime can be overcome, achieving a purely ...
Flavio Giorgianni, Joe Sakai, Stefano Lupi   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Combined Rehabilitation Promotes the Recovery of Structural and Functional Features of Healthy Neuronal Networks after Stroke

Cell Reports, 2019
Summary: Rehabilitation is considered the most effective treatment for promoting the recovery of motor deficits after stroke. One of the most challenging experimental goals is to unambiguously link brain rewiring to motor improvement prompted by ...
Anna Letizia Allegra Mascaro, Emilia Conti, Stefano Lai, Antonino Paolo Di Giovanna, Cristina Spalletti, Claudia Alia, Alessandro Panarese, Alessandro Scaglione, Leonardo Sacconi, Silvestro Micera, Matteo Caleo, Francesco Saverio Pavone   +11 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Cavity optomechanics in a fiber cavity: the role of stimulated Brillouin scattering

New Journal of Physics, 2022
We study the role of stimulated Brillouin scattering in a fiber cavity by numerical simulations and a simple theoretical model and find good agreement between experiment, simulation and theory.
A Beregi, A Pontin, P F Barker
doaj   +1 more source

Spectral shearing of quantum light pulses by electro-optic phase modulation

, 2017
Frequency conversion of non-classical light enables robust encoding of quantum information based upon spectral multiplexing that is particularly well-suited to integrated-optics platforms.
Karpinski, Michal, Smith, Brian J., Soeller, Christoph, Wright, Laura J.   +3 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source