Results 81 to 90 of about 56,421 (265)

Single Sr Atoms in Optical Tweezer Arrays for Quantum Simulation

Atoms
We report on the realization of a platform for trapping and manipulating individual 88Sr atoms in optical tweezers. A first cooling stage based on a blue shielded magneto-optical trap (MOT) operating on the |1S0⟩→|1P1⟩ transition at 461 nm enables us to ...
Veronica Giardini, Luca Guariento, Andrea Fantini, Shawn Storm, Massimo Inguscio, Jacopo Catani, Giacomo Cappellini, Vladislav Gavryusev, Leonardo Fallani   +8 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Acousto-optic deflectors in experimental neuroscience: overview of theory and applications

JPhys Photonics
Cutting-edge methodologies and techniques are required to understand complex neuronal dynamics and pathological mechanisms. Among them, optical tools stand out due to their combination of non-invasiveness, speed, and precision.
Pietro Ricci, Giuseppe Sancataldo, Vladislav Gavryusev, Francesco Saverio Pavone, Peter Saggau, Martí Duocastella   +5 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Frequency-bin entanglement-based Quantum Key Distribution

npj Quantum Information
Entanglement is an essential ingredient in many quantum communication protocols. In particular, entanglement can be exploited in quantum key distribution (QKD) to generate two correlated random bit strings whose randomness is guaranteed by the nonlocal ...
Noemi Tagliavacche, Massimo Borghi, Giulia Guarda, Domenico Ribezzo, Marco Liscidini, Davide Bacco, Matteo Galli, Daniele Bajoni   +7 more
doaj   +1 more source

Direct Generation and Non-Hermitian Regulation of Energy-Time-Polarization-Hyper-Entangled Quadphotons

Sensors
Entangled multiphoton is an ideal resource for quantum information technology. Here, narrow-bandwidth hyper-entangled quadphoton is theoretically demonstrated by quantizing degenerate Zeeman sub states through spontaneous eight-wave mixing (EWM) in a hot
Rui Zhuang, Siqiang Zhang, Guobin Liu, Zhou Feng, Qingyu Chen, Sinong Liu, Yanpeng Zhang   +6 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Corrigendum: Bessel Beam Illumination Reduces Random and Systematic Errors in Quantitative Functional Studies Using Light-Sheet Microscopy

Frontiers in Cellular Neuroscience, 2019
M. Caroline Müllenbroich, M. Caroline Müllenbroich, Lapo Turrini, Ludovico Silvestri, Ludovico Silvestri, Tommaso Alterini, Ali Gheisari, Natascia Tiso, Francesco Vanzi, Francesco Vanzi, Leonardo Sacconi, Leonardo Sacconi, Francesco S. Pavone, Francesco S. Pavone, Francesco S. Pavone   +14 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source