Results 91 to 100 of about 12,775 (195)

Automated Surface‐Based Segmentation of Deep Gray Matter Regions Based on Diffusion Tensor Images Reveals Unique Age Trajectories Over the Healthy Lifespan

open access: yesNMR in Biomedicine, Volume 39, Issue 8, August 2026.
This paper introduces a novel, automated deep gray matter segmentation method that relies exclusively on diffusion‐weighted imaging, eliminating the need for T1‐weighted images. When applied to a lifespan cohort from ages 5 to 90, the technique successfully mapped distinct, nonlinear developmental and aging trajectories for microstructural diffusion ...
Graham Little   +2 more
wiley   +1 more source

Test-Retest Reliability of Diffusion Measures Extracted Along White Matter Language Fiber Bundles Using HARDI-Based Tractography

open access: yesFrontiers in Neuroscience, 2019
High angular resolution diffusion imaging (HARDI)-based tractography has been increasingly used in longitudinal studies on white matter macro- and micro-structural changes in the language network during language acquisition and in language impairments ...
Mariem Boukadi   +14 more
doaj   +1 more source

Dissecting the Strain and Sex Specific Connectome Signatures of Unanesthetized C57BL/6J and DBA/2J Mice Using Magnetic Resonance Imaging

open access: yesGenes, Brain and Behavior, Volume 25, Issue 4, August 2026.
C57BL/6J and DBA/2J mice were used to investigate strain and sex‐specific features of the brain connectome in awake animals using magnetic resonance imaging (MRI). By combining resting‐state and diffusion MRI, we found significant differences in the motor, sensory, limbic, and salience networks between C57BL/6J and DBA/2J mice.
Tanzil M. Arefin   +4 more
wiley   +1 more source

Feasibility study to unveil the potential: considerations of constrained spherical deconvolution tractography with unsedated neonatal diffusion brain MRI data

open access: yesFrontiers in Radiology
PurposeThe study aimed to (1) assess the feasibility constrained spherical deconvolution (CSD) tractography to reconstruct crossing fiber bundles with unsedated neonatal diffusion MRI (dMRI), and (2) demonstrate the impact of spatial and angular ...
Anouk S. Verschuur   +11 more
doaj   +1 more source

Directionality of longitudinal associations between frontostriatal structural connectivity and depressive symptoms in adolescent girls

open access: yesJournal of Child Psychology and Psychiatry, Volume 67, Issue 8, Page 1361-1370, August 2026.
Background Individual differences in the structure and function of the frontostriatal reward network have been related to depression. However, there is a strong need for prospective, longitudinal studies aiming to understand the role of frontostriatal networks in depression in a developmental context.
Marjolein E.A. Barendse   +3 more
wiley   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

open access: yesAnnals of Clinical and Translational Neurology, Volume 13, Issue 7, Page 1320-1334, July 2026.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang   +10 more
wiley   +1 more source

Modular brain networks shape amyloid‐driven tau spread and cognitive decline

open access: yesAlzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract INTRODUCTION Alzheimer's disease involves trans‐synaptic spread of tau pathology from temporal lobe epicenters, driven by amyloid beta (Aβ) deposition. How modular brain network architecture shapes this process and the ensuing cognitive decline remains incompletely understood.
Fabian Hirsch   +11 more
wiley   +1 more source

Genetic architecture of the limbic white matter microstructure in aging and Alzheimer's Disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract INTRODUCTION Limbic white matter (WM) abnormalities are prevalent in aging and Alzheimer's disease (AD), but genetic drivers are unclear. METHODS In 2614 older adults (mean age ± SD: 73.7 ± 9.8 years; 26% cognitively impaired) from seven harmonized cohorts enriched for cognitive impairment, we quantified free‐water–corrected diffusion MRI ...
Anna S Lorenz   +47 more
wiley   +1 more source

Conus Medullaris Teratoma with Utilization of Fiber Tractography: Case Report

open access: yesJournal of Neurological Surgery Reports, 2015
Objective Conus medullaris teratomas are very rare tumors. Traditional preoperative diagnosis depended on the findings from magnetic resonance imaging (MRI).
Fahad Alkherayf   +2 more
doaj   +1 more source

AI‐Driven Mapping of Seizure Spread Patterns

open access: yesAnnals of Neurology, Volume 100, Issue 1, Page 59-73, July 2026.
Objective The focus of epilepsy research has largely been on seizure onset; however, physicians typically examine the patterns of seizure spread past seizure onset as well. This study aims to align automated seizure analysis with clinical practice, leverage deep learning to standardize seizure annotations that varies among physicians, and understand ...
Andrew Y. Revell   +13 more
wiley   +1 more source

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