Results 31 to 40 of about 43,320 (260)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Weighting fibre and morphological traits in a genetic index for an alpaca breeding programme

Animal, 2014
Nowadays, the fibre diameter (FD) is considered the main selection objective in alpaca populations all over the world. International Committee for Animal Recording recommendations define the FD and its CV as the first two traits to be considered in ...
J.P. Gutiérrez, I. Cervantes, M.A. Pérez-Cabal, A. Burgos, R. Morante   +4 more
doaj   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

FEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Model to Predict Polymer Fibre Diameter during Melt Spinning

Advances in Polymer Technology, 2023
Polymeric materials were evaluated with regard to their spinnability and respective fibre diameters. A modified single fibre spinning device was firstly used to derive a novel generalised model, utilising process parameters (die diameter, throughput, and
Alexander M. Bier, Michael Redel, Dirk W. Schubert   +2 more
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Theoretical and Computational Analysis on Double-End Submerged Hollow Fibre Membrane Modules

Energies, 2018
This paper studies the potential increase in permeate output flow rate that submerged hollow fibres can achieve when operating in double-end suction.
Keng Boon Lim, Hui An, Peng Cheng Wang, Guiqin Liu, Simon Ching Man Yu   +4 more
doaj   +1 more source

White Matter and Perivascular Imaging Changes in Alzheimer's Disease and Cerebral Amyloid Angiopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peak‐width of skeletonized mean diffusivity (PSMD) and diffusion tensor imaging–analysis along the perivascular space (DTI‐ALPS), reflecting white matter integrity and glymphatic function, are altered in Alzheimer's disease (AD).
Debina Laishram, Guangwei Du, Sangam Kanekar, Nandakumar Nagaraja   +3 more
wiley   +1 more source

Thermomechanical Fatigue and Creep–Fatigue Interaction of Inconel 718 Additively Manufactured by Laser Beam Powder Bed Fusion

Advanced Engineering Materials, EarlyView.
Thermomechanical fatigue tests of laser beam powder bed fusion (PBF‐LB) Inconel 718 show that the additively manufactured material reaches almost the lifetimes of conventionally‐rolled material under no‐dwell conditions. Introducing dwell times at the maximum temperature markedly reduces the lifetimes due to pronounced grain boundary sliding associated
Stefan Guth, Tomáš Babinský, Jan Lars Riedel, Wen Hao Kan, Aijun Huang, Martin Heilmaier, Ivo Šulák   +6 more
wiley   +1 more source

A Study on Wicking in Natural Staple Yarns

Journal of Natural Fibers, 2017
In this study, natural staple yarns of cotton and wool were investigated for wicking properties. Fibre packing density reflected by yarn wicking rates was measured in ply cotton yarns.
Q. Li, J. J. Wang, C. J. Hurren
doaj   +1 more source

Genetic analysis for growth and wood fiber properties in second generation clones of Acacia auriculiformis

Electronic Journal of Plant Breeding, 2021
Genetic variability of growth, wood density and fibre characters was determined in twenty second-generation clones of Acacia auriculiformis grown at IFGTB- Field Research Station, Neyvli, Tamil Nadu, India. Total volume revealed high phenotypic (29.10 %)
A. Mayavel1 ⃰ , S. Esakkiammal1, P. Chitra1, Asish K Binodh2 and R. Kamalakannan3
doaj   +1 more source