Results 1 to 10 of about 127,967 (338)

A fibril-scale visco-hyperelastic model for the mechanics of vocal-fold tissues [PDF]

Frontiers in Bioengineering and Biotechnology
IntroductionModeling the mechanics of human vocal folds during phonation is a challenging task. This is partly due to the mechanics of their soft and highly anisotropic fibrous tissues, which undergoes finite strains with both elasticity and strain-rate ...
Alberto Terzolo, Lucie Bailly, Laurent Orgéas   +2 more
doaj   +2 more sources

Amyloid Fibrils and Their Applications: Current Status and Latest Developments [PDF]

Nanomaterials
Amyloid fibrils are one of the important forms of protein aggregates, first discovered in the pathological brain tissues of patients with various neurodegenerative diseases. They are considered the core pathological markers of different neurodegenerative
Bingxu Liu, Hongnan Zhang, Xiaohong Qin
doaj   +2 more sources

Identification of small molecule dimethyoxyphenyl piperazine inhibitors of alpha-synuclein fibril growth [PDF]

Scientific Reports
Alpha-synuclein (asyn) fibril accumulation is the defining feature of Parkinson disease and is a target for disease-modifying treatments. One therapeutic strategy to reduce fibril accumulation is inhibition of asyn fibril growth. We developed a sensitive
Helen Hwang, Dhruva D. Dhavale, Sarah J. Wang, Ajay Guduputi, John M. Beale, Nigel J. Cairns, Paul T. Kotzbauer   +6 more
doaj   +2 more sources

Dialdehyde Cellulose Solution as Reducing Agent: Preparation of Uniform Silver Nanoparticles and In Situ Synthesis of Antibacterial Composite Films with High Barrier Properties

Molecules, 2023
The demand for antimicrobial materials is gradually increasing due to the threat of infections and diseases caused by microorganisms. Silver nanoparticles (AgNPs) are widely used because of their broad-spectrum antimicrobial properties, but their ...
Jinsong Zeng, Xinyi Xiong, Fugang Hu, Jinpeng Li, Pengfei Li   +4 more
doaj   +1 more source

Neurons with Cat’s Eyes: A Synthetic Strain of α-Synuclein Fibrils Seeding Neuronal Intranuclear Inclusions

Biomolecules, 2022
The distinct neuropathological features of the different α-Synucleinopathies, as well as the diversity of the α-Synuclein (α-Syn) intracellular inclusion bodies observed in post mortem brain sections, are thought to reflect the strain diversity ...
Francesca De Giorgi, Muhammed Bilal Abdul-Shukkoor, Marianna Kashyrina, Leslie-Ann Largitte, Francesco De Nuccio, Brice Kauffmann, Alons Lends, Florent Laferrière, Sébastien Bonhommeau, Dario Domenico Lofrumento, Luc Bousset, Erwan Bezard, Thierry Buffeteau, Antoine Loquet, François Ichas   +14 more
doaj   +1 more source

Rational Generation of Monoclonal Antibodies Selective for Pathogenic Forms of Alpha-Synuclein

Biomedicines, 2022
Misfolded toxic forms of alpha-synuclein (α-Syn) have been implicated in the pathogenesis of synucleinopathies, including Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA).
Ebrima Gibbs, Beibei Zhao, Andrei Roman, Steven S. Plotkin, Xubiao Peng, Shawn C. C. Hsueh, Adekunle Aina, Jing Wang, Clay Shyu, Calvin K. Yip, Sung-Eun Nam, Johanne M. Kaplan, Neil R. Cashman   +12 more
doaj   +1 more source

Extraction of Micro- and Nano-Fibrils from Nylon 6/Polypropylene Grafted with Maleic Anhydride/Polypropylene Blended Films [PDF]

علوم و تکنولوژی پلیمر, 2013
Atechnical feasibility study has been conducted on production of nano- and micro-fibrils from nylon 6/polypropylene grafted with maleic anhydride/polypropylene blended films.
E. Bagheban Kochak, E. Fallahi, M. Haghighat Kish   +2 more
doaj   +1 more source

Change in Collagen Fibril Diameter Distribution of Bovine Anterior Cruciate Ligament upon Injury Can Be Mimicked in a Nanostructured Scaffold

Molecules, 2021
More than 200,000 people are suffering from Anterior Cruciate Ligament (ACL) related injuries each year in the US. There is an unmet clinical demand for improving biological attachment between grafts and the host tissue in addition to providing ...
Zhuldyz Beisbayeva, Ainur Zhanbassynova, Gulzada Kulzhanova, Fariza Mukasheva, Cevat Erisken   +4 more
doaj   +1 more source

Multiscale Characterization of Type I Collagen Fibril Stress–Strain Behavior under Tensile Load: Analytical vs. MD Approaches

Bioengineering, 2022
Type I collagen is one of the most important proteins in the human body because of its role in providing structural support to the extracellular matrix of the connective tissues.
Afif Gouissem, Raouf Mbarki, Fadi Al Khatib, Malek Adouni   +3 more
doaj   +1 more source

Morphology Research of Windmill Palm (Trachycarpus fortunei) Material [PDF]

Kemija u Industriji, 2015
Windmill palm (Trachycarpus fortunei) fibre was obtained from different parts of windmill-palm trunk sheath and then treated by sodium hydroxide solution and hydrogen peroxide to obtain the treated palm fibril.
C.-J. Chen, Y. Zhang, J.-J. Jia, M.-X. Wang , G.-H. Wang   +4 more
doaj   +1 more source