Results 121 to 130 of about 114,998 (297)

Stop-and-go kinetics in amyloid fibrillation [PDF]

open access: yesarXiv, 2009
Many human diseases are associated with protein aggregation and fibrillation. We present experiments on in vitro glucagon fibrillation using total internal reflection fluorescence microscopy, providing real-time measurements of single-fibril growth. We find that amyloid fibrils grow in an intermittent fashion, with periods of growth followed by long ...
arxiv  

Mechanical Deformation Mechanisms and Properties of Prion Fibrils Probed by Atomistic Simulations

open access: yesNanoscale Research Letters, 2017
Prion fibrils, which are a hallmark for neurodegenerative diseases, have recently been found to exhibit the structural diversity that governs disease pathology.
Bumjoon Choi   +4 more
doaj   +1 more source

Design and Evaluation of 3D‐Printed Polylactic Acid Composites Reinforced with Biodegradable Bamboo Powder and Jute Powder

open access: yesAdvanced Engineering Materials, EarlyView.
The study investigates 3D‐printed polylactic acid (PLA) composites with biodegradable bamboo and jute powder fillers. Mechanical, thermal, structural properties, and rheological behavior are discussed to evaluate composite performance. Morphological characterization indicates uniform dispersion and adhesion of the fillers in the PLA matrix with the ...
Vimukthi Dananjaya   +4 more
wiley   +1 more source

Low‐Velocity Penetration Impact Behavior of Triply Periodic Minimal Surface Strut‐Based Lattices

open access: yesAdvanced Engineering Materials, EarlyView.
Triply periodic minimal surface (TPMS)‐based lattices are gaining attention for their multifunctional properties in applications as aeronautics and automotive, which involve low‐velocity impact loading. This work evaluates the low‐velocity penetration impact behavior of five distinct TPMS architectures.
Lucía Doyle   +2 more
wiley   +1 more source

Direct Ink Writing of Conductive Hydrogels

open access: yesAdvanced Functional Materials, EarlyView.
This review examines the use of direct ink writing (DIW) for fabricating conductive hydrogels with customizable 3D structures. It outlines the rheological requirements for successful DIW, followed by an exploration of the materials and ink formulations used to impart electronic and/or ionic conductivity to hydrogels while maintaining printability ...
Monica Ho   +6 more
wiley   +1 more source

Energy landscape analysis of cardiac fibrillation wave dynamics using pairwise maximum entropy model [PDF]

open access: yesarXiv, 2018
Cardiac fibrillation is characterized by chaotic and disintegrated spiral wave dynamics patterns, whereas sinus rhythm shows synchronized excitation patterns. To determine functional correlations among cardiomyocytes during complex fibrillation states, we applied a pairwise maximum entropy model (MEM) to the 2D numerical simulation data of human atrial
arxiv  

Non-fibril form but not fibril form of human islet amyloid polypeptide 8-20 changes brain functions in mice.

open access: yesPLoS ONE
Whether fibril formation increases or decreases cytotoxicity remains unclear. Aggregation of human islet amyloid polypeptide (hIAPP), a pivotal regulator of glucose homeostasis, impairs the function and viability of pancreatic β cells.
Hinaho Suginoma   +5 more
doaj   +1 more source

Physical basis of amyloid fibril polymorphism

open access: yesNature Communications, 2018
Amyloid fibril structures can display polymorphism. Here the authors reveal the cryo-EM structures of several different fibril morphologies of a peptide derived from an amyloidogenic immunoglobulin light chain and present a mathematical analysis of ...
William Close   +9 more
doaj   +1 more source

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