Results 121 to 130 of about 114,998 (297)
Stop-and-go kinetics in amyloid fibrillation [PDF]
Many human diseases are associated with protein aggregation and fibrillation. We present experiments on in vitro glucagon fibrillation using total internal reflection fluorescence microscopy, providing real-time measurements of single-fibril growth. We find that amyloid fibrils grow in an intermittent fashion, with periods of growth followed by long ...
arxiv
Mechanical Deformation Mechanisms and Properties of Prion Fibrils Probed by Atomistic Simulations
Prion fibrils, which are a hallmark for neurodegenerative diseases, have recently been found to exhibit the structural diversity that governs disease pathology.
Bumjoon Choi+4 more
doaj +1 more source
The relation between the cyto‐reticulum and the fibril bundles in the heart muscle cell of the chick [PDF]
H. L. Wieman
openalex +1 more source
The study investigates 3D‐printed polylactic acid (PLA) composites with biodegradable bamboo and jute powder fillers. Mechanical, thermal, structural properties, and rheological behavior are discussed to evaluate composite performance. Morphological characterization indicates uniform dispersion and adhesion of the fillers in the PLA matrix with the ...
Vimukthi Dananjaya+4 more
wiley +1 more source
Low‐Velocity Penetration Impact Behavior of Triply Periodic Minimal Surface Strut‐Based Lattices
Triply periodic minimal surface (TPMS)‐based lattices are gaining attention for their multifunctional properties in applications as aeronautics and automotive, which involve low‐velocity impact loading. This work evaluates the low‐velocity penetration impact behavior of five distinct TPMS architectures.
Lucía Doyle+2 more
wiley +1 more source
Lesions of the Primitive Fibrils of the Voluntary Muscles in Progressive Muscular Atrophy and in Lead Paralysis [PDF]
NULL AUTHOR_ID
openalex +1 more source
Direct Ink Writing of Conductive Hydrogels
This review examines the use of direct ink writing (DIW) for fabricating conductive hydrogels with customizable 3D structures. It outlines the rheological requirements for successful DIW, followed by an exploration of the materials and ink formulations used to impart electronic and/or ionic conductivity to hydrogels while maintaining printability ...
Monica Ho+6 more
wiley +1 more source
Energy landscape analysis of cardiac fibrillation wave dynamics using pairwise maximum entropy model [PDF]
Cardiac fibrillation is characterized by chaotic and disintegrated spiral wave dynamics patterns, whereas sinus rhythm shows synchronized excitation patterns. To determine functional correlations among cardiomyocytes during complex fibrillation states, we applied a pairwise maximum entropy model (MEM) to the 2D numerical simulation data of human atrial
arxiv
Whether fibril formation increases or decreases cytotoxicity remains unclear. Aggregation of human islet amyloid polypeptide (hIAPP), a pivotal regulator of glucose homeostasis, impairs the function and viability of pancreatic β cells.
Hinaho Suginoma+5 more
doaj +1 more source
Physical basis of amyloid fibril polymorphism
Amyloid fibril structures can display polymorphism. Here the authors reveal the cryo-EM structures of several different fibril morphologies of a peptide derived from an amyloidogenic immunoglobulin light chain and present a mathematical analysis of ...
William Close+9 more
doaj +1 more source