Results 41 to 50 of about 114,998 (297)
Isotropic-nematic phase transition in amyloid fibrilization [PDF]
Physical Review E 80, 031902 (2009), 2009 We carry out a theoretical study on the isotropic-nematic phase transition and phase separation in amyloid fibril solutions. Borrowing the thermodynamic model employed in the study of cylindrical micelles, we investigate the variations in the fibril length distribution and phase behavior with respect to changes in the protein concentration, fibril's ...
arxiv +1 more source
MoleculesGiven the widespread prevalence of viruses, there is an escalating demand for antimicrobial composites. Although the composite of dialdehyde cellulose and silver nanoparticles (DAC@Ag1) exhibits excellent antibacterial properties, its weak mechanical ...
Jinsong Zeng +7 more
doaj +1 more source
Journal of Dairy Science, 2022 : Amyloid fibrils have many excellent functional properties that facilitate their applications in the food industry. There are 2 pathways for whey protein concentrate (WPC) to form amyloid fibril aggregates: spontaneous pathway and nuclear induction ...
Xiaotong Yang +7 more
doaj
Frontiers in Bioengineering and Biotechnology, 2020 Human aging is accompanied by a relevant increase in age-associated chronic pathologies, including neurodegenerative and metabolic diseases. The appearance and evolution of numerous neurodegenerative diseases is paralleled by the appearance of ...
Jose A. del Rio +8 more
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Alternative Structures of α-Synuclein
Molecules, 2020 The object of our analysis is the structure of alpha-synuclein (ASyn), which, under in vivo conditions, associates with presynaptic vesicles. Misfolding of ASyn is known to be implicated in Parkinson’s disease.
Dawid Dułak +4 more
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Unraveling capillary interaction and viscoelastic response in atomic force microscopy of hydrated collagen fibrils [PDF]
Nanoscale 9 (2017) 1244-1256, 2019 The mechanical properties of collagen fibrils depend on the amount and the distribution of water molecules within the fibrils. Here, we use atomic force microscopy (AFM) to study the effect of hydration on the viscoelastic properties of reconstituted type I collagen fibrils in air with controlled relative humidity. With the same AFM tip, we investigate
arxiv +1 more source
Atrial Fibrillation Detection Using RR-Intervals for Application in Photoplethysmographs [PDF]
arXiv, 2023 Atrial Fibrillation is a common form of irregular heart rhythm that can be very dangerous. Our primary goal is to analyze Atrial Fibrillation data within ECGs to develop a model based only on RR-Intervals, or the length between heart-beats, to create a real time classification model for Atrial Fibrillation to be implemented in common heart-rate ...
arxiv
Why are Functional Amyloids Non-Toxic in Humans?
Biomolecules, 2017 Amyloids were first identified in association with amyloidoses, human diseases in which proteins and peptides misfold into amyloid fibrils. Subsequent studies have identified an array of functional amyloid fibrils that perform physiological roles in ...
Matthew P. Jackson, Eric W. Hewitt
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PLoS ONE, 2021 Assembly of the extracellular matrix protein fibronectin (FN) into insoluble, viscoelastic fibrils is a critical step during embryonic development and wound healing; misregulation of FN fibril assembly has been implicated in many diseases, including ...
Seth H Weinberg +2 more
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The architecture of amyloid-like peptide fibrils revealed by X-ray scattering, diffraction and electron microscopy [PDF]
, 2015 Structural analysis of protein fibrillation is inherently challenging. Given the crucial role of fibrils in amyloid diseases, method advancement is urgently needed.
Annette E. Langkilde +50 more
core +1 more source