Results 31 to 40 of about 750,552 (306)

Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins.

open access: yesNew England Journal of Medicine, 1998
BACKGROUND Atrial fibrillation, the most common sustained cardiac arrhythmia and a major cause of stroke, results from simultaneous reentrant wavelets. Its spontaneous initiation has not been studied.
Michael Haïssaguerre   +9 more
semanticscholar   +1 more source

Uniform spatial distribution of collagen fibril radii within tendon implies local activation of pC-collagen at individual fibrils [PDF]

open access: yesPhysical Biology, v. 13 (2016) 046008, 2016
Collagen fibril cross-sectional radii show no systematic variation between the interior and the periphery of fibril bundles, indicating an effectively constant rate of collagen incorporation into fibrils throughout the bundle. Such spatially homogeneous incorporation constrains the extracellular diffusion of collagen precursors from sources at the ...
arxiv   +1 more source

A resorcinarene for inhibition of Aβ fibrillation. [PDF]

open access: yes, 2017
Amyloid-β peptides (Aβ) fibrillation is the hallmark of Alzheimer's disease (AD). However, it has been challenging to discover potent agents in order to inhibit Aβ fibrillation.
Han, Xu   +8 more
core   +1 more source

Edoxaban versus warfarin in patients with atrial fibrillation.

open access: yesNew England Journal of Medicine, 2013
BACKGROUND Edoxaban is a direct oral factor Xa inhibitor with proven antithrombotic effects. The long-term efficacy and safety of edoxaban as compared with warfarin in patients with atrial fibrillation is not known.
R. Giugliano   +20 more
semanticscholar   +1 more source

Rivaroxaban versus warfarin in nonvalvular atrial fibrillation.

open access: yesNew England Journal of Medicine, 2011
BACKGROUND The use of warfarin reduces the rate of ischemic stroke in patients with atrial fibrillation but requires frequent monitoring and dose adjustment.
M. Patel   +15 more
semanticscholar   +2 more sources

Temperature diagnostics of chromospheric fibrils [PDF]

open access: yesA&A 672, A89 (2023), 2023
Context. Chromospheric fibrils are thin and elongated structures that connect nearby photospheric magnetic field concentrations of opposite polarities. Aims. We assess the possibilities and drawbacks related to the use of current instrumentation and inversion techniques to infer the thermodynamic structure of chromospheric fibrils. Methods. We employed
arxiv   +1 more source

Amyloid fibril formation kinetics of low-pH denatured bovine PI3K-SH3 monitored by three different NMR techniques

open access: yesFrontiers in Molecular Biosciences, 2023
Introduction: Misfolding of amyloidogenic proteins is a molecular hallmark of neurodegenerative diseases in humans. A detailed understanding of the underlying molecular mechanisms is mandatory for developing innovative therapeutic approaches.
Luis Gardon   +14 more
doaj   +1 more source

The Value of Voltage Histogram Analysis Derived Right Atrial Scar Burden in the Prediction of Left Atrial Scar Burden

open access: yesCardiology Research and Practice, 2020
Introduction. Growing evidence suggests that fibrotic changes can be observed in atrial fibrillation (AF) in both atria. Quantification of the scar burden during electroanatomical mapping might have important therapeutic and prognostic consequences ...
Szilvia Herczeg   +7 more
doaj   +1 more source

RHYTHM-AF: design of an international registry on cardioversion of atrial fibrillation and characteristics of participating centers [PDF]

open access: yes, 2012
BACKGROUND Atrial fibrillation is a serious public health problem posing a considerable burden to not only patients, but the healthcare environment due to high rates of morbidity, mortality, and medical resource utilization. There are limited data on the
AJ Camm   +36 more
core   +3 more sources

Amyloid Fibril Solubility [PDF]

open access: yesJ. Phys. Chem. B, 2015, 119 (46), pp 14631-14636, 2015
It is well established that amyloid fibril solubility is protein specific, but how solubility depends on the interactions between the fibril building blocks is not clear. Here we use a simple protein model and perform Monte Carlo simulations to directly measure the solubility of amyloid fibrils as a function of the interaction between the fibril ...
arxiv   +1 more source

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