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Atrial fibrillation (AF) is the most common sustained cardiac rhythm disorder, and increases in prevalence with increasing age and the number of cardiovascular comorbidities. AF is characterized by a rapid and irregular heartbeat that can be asymptomatic or lead to symptoms such as palpitations, dyspnoea and dizziness.
Lip, Gregory +10 more
+13 more sources
Fibrillation of transferrin [PDF]
The nature of fibrillar deposits from aqueous solutions of human serum and recombinant human transferrin on mica and carbon-coated formvar surfaces has been investigated.Atomic force microscopy showed that the deposition of recombinant transferrin onto the hydrophilic surface of mica resulted in the formation of a monolayer-thick film composed of ...
C. Booyjzsen +6 more
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Prognostications of Fibrillations [PDF]
See related article, p 1210. Post-hospital evaluation for the cause of ischemic stroke has gained increased attention in the last decade, particularly the search for paroxysmal atrial fibrillation. Initial studies of Holter monitoring documented rates of atrial fibrillation of ≈5% or 1 in 20 patients.1 Further, prolonged monitoring for as long as 1 ...
Silver, Brian, Windecker, Stephan
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Fibril Breaking Accelerates α-Synuclein Fibrillization [PDF]
The formation of amyloid fibrils of α-synuclein (αSyn), the key protein in Parkinson's disease, is an autocatalytic process that is seeded by mature αSyn fibrils. Based on systematic measurements of the dependence of the fibril growth rate on the concentrations of monomers and preformed fibrillar seeds, we propose a mechanism of αSyn aggregation that ...
Shvadchak, Volodymyr V. +2 more
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BackgroundCryoballoon pulmonary vein isolation (PVI) has emerged as an alternative to radiofrequency PVI for atrial fibrillation (AF). Data are lacking to define the rates and predictors of complications, particularly phrenic nerve injury (PNI).
Emily N. Guhl +10 more
doaj +1 more source
Physiological Assessment of Ventricular Myocardial Voltage Using Omnipolar Electrograms
BackgroundCharacterization of myocardial health by bipolar electrograms are critical for ventricular tachycardia therapy. Dependence of bipolar electrograms on electrode orientation may reduce reliability of voltage assessment along the plane of ...
Karl Magtibay +11 more
doaj +1 more source
Atrial fibrillation (AF) is a hetrogeneous disease that may present in many forms. Advances in our understanding of the mechanism responsible for AF have led to exciting new therapies that may soon provide a definitive cure.
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Introduction: Misfolding of amyloidogenic proteins is a molecular hallmark of neurodegenerative diseases in humans. A detailed understanding of the underlying molecular mechanisms is mandatory for developing innovative therapeutic approaches.
Luis Gardon +14 more
doaj +1 more source
Atrial Fibrillation Degenerates Into Ventricular Fibrillation
![Figure][1] A 43-year-old man with paroxysmal atrial fibrillation (AF) and an implantable cardioverter defibrillator (ICD) placed for documented ventricular fibrillation (VF), presented with an ICD shock. Ventricular pre-excitation was not present.
Venkataraman, Ganesh +1 more
openaire +2 more sources
Introduction. Growing evidence suggests that fibrotic changes can be observed in atrial fibrillation (AF) in both atria. Quantification of the scar burden during electroanatomical mapping might have important therapeutic and prognostic consequences ...
Szilvia Herczeg +7 more
doaj +1 more source

