Results 61 to 70 of about 6,142 (190)

Neuroprotection and Axonal Regeneration via ECM‐Mimetic Nanofibers Incorporating Metal–Phenolic Network Nanoparticles Toward Spinal Cord Injury Repair

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
Metal–phenolic network (MPN) nanoparticles with neuroprotective functions are integrated into decellularized extracellular matrix (dECM) to obtain biomimetic composite fibrous scaffold MPN@dECM NFs by electrospinning, which protects spared neurons from secondary degeneration by suppressing excitotoxicity and inflammation, and promotes directional ...
Shu Chen   +4 more
wiley   +1 more source

Circular RNAs in Diabetic Foot Ulcers: A Scoping Review of Clinical, Preclinical, and In Silico Evidence on Diagnostic and Therapeutic Potentials

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 1, January 2026.
This figure summarises circRNAs identified as therapeutic or pathogenic targets in animal models of diabetic foot ulcers. Protective circRNAs delivered via exosomes, hypoxia‐preconditioned exosomes, or lipid nanoparticles promote angiogenesis, autophagy, and oxidative stress resistance. In contrast, silencing of pathogenic circRNAs such as circ_0005654
Amir Reza Ghafourian   +6 more
wiley   +1 more source

Genetic differences between primary colorectal cancer and its paired synchronous and metachronous metastases

open access: yesInternational Journal of Cancer, Volume 158, Issue 1, Page 120-130, 1 January 2026.
What's new? Colorectal cancer (CRC) frequently metastasizes to the liver, either synchronously with primary diagnosis or metachronously, after variable time intervals. Although implicated, the role of genetic factors in driving synchronous and metachronous disease progression remains uncertain.
Marie Rajtmajerova   +16 more
wiley   +1 more source

The N-terminal Part of Arabidopsis thaliana Starch Synthase 4 Determines the Localization and Activity of the Enzyme*

open access: yesJournal of Biological Chemistry, 2016
Starch synthase 4 (SS4) plays a specific role in starch synthesis because it controls the number of starch granules synthesized in the chloroplast and is involved in the initiation of the starch granule.
Sandy Raynaud   +3 more
semanticscholar   +1 more source

Collagen XV preserves heart function and protects from pathological remodelling after myocardial infarction

open access: yesThe FEBS Journal, Volume 293, Issue 2, Page 418-442, January 2026.
We analysed collagen XV expression in myocardial infarct samples and assessed how its deficiency affects cardiac responses, such as fibrogenesis and tissue stiffness. In mice, damage caused by myocardial infarction is exacerbated in the absence of collagen XV and leads to pathological remodelling and more severe left ventricle dysfunction (left panel ...
Sanna‐Maria Karppinen   +15 more
wiley   +1 more source

Calcium binding to fibrillin? [PDF]

open access: bronze, 1991
Penny A. Handford   +2 more
openalex   +1 more source

The Prodomain of BMP-7 Targets the BMP-7 Complex to the Extracellular Matrix*

open access: yesJournal of Biological Chemistry, 2005
Biochemical and biophysical methods are used to show that BMP-7 is secreted as a stable complex consisting of the processed growth factor dimer noncovalently associated with its two prodomain propeptide chains and that the BMP-7 complex is structurally ...
K. Gregory   +6 more
semanticscholar   +1 more source

A guide to building the matrisome interactome: from computational predictions to experimental validation

open access: yesThe FEBS Journal, Volume 293, Issue 1, Page 42-70, January 2026.
This guide proposes a roadmap combining state‐of‐the‐art computational and experimental approaches (including biophysical, biochemical, and imaging techniques) to identify, characterize, and contextualize extracellular matrix (ECM) protein interactions.
Leanna Leverton   +4 more
wiley   +1 more source

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