Results 61 to 70 of about 27,009 (261)

Advanced 3D Platforms for Modeling CNS Neuroinflammation: Cell Integration, Techniques, and Challenges

open access: yesAdvanced Healthcare Materials, EarlyView.
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi   +2 more
wiley   +1 more source

Differences in coagulation-relevant parameters: Comparing cryoprecipitate and a human fibrinogen concentrate

open access: yesPLoS ONE, 2023
Background Variable fibrinogen content within cryoprecipitate makes accurate dosing challenging in patients with coagulopathic bleeding, in addition to pathogen transmission risks associated with its administration.
Sophia Stanford   +7 more
doaj  

Detection of fibrinogen-fibrin degradation products by counterelectrophoresis [PDF]

open access: yesJournal of Clinical Pathology, 1972
Counterelectrophoresis using a discontinuous buffer system permits detection of fibrinogen-fibrin degradation products (FDP) under a variety of clinical circumstances. The method is sensitive, reliable, and is easily performed using conventional equipment in any clinical laboratory assuming the responsibility for assaying fibrinogen-fibrin degradation ...
openaire   +2 more sources

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

open access: yesAdvanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach   +7 more
wiley   +1 more source

A Versatile Engineering Platform for the Fabrication of Prosthetic Venous Valves Using Electrospinning

open access: yesAdvanced Healthcare Materials, EarlyView.
Percutaneous prosthetic venous valves are fabricated by embedding stents in an electrospun matrix that extends luminally to form leaflets. The design shields leaflets from hyperplastic cells, isolates struts from blood contact, and avoids discrete anchoring points.
Dario Arcuti   +6 more
wiley   +1 more source

Fibrin/Fibrinogen Degradation Products [PDF]

open access: yesArchives of Disease in Childhood, 1970
W. S. Uttley, A. G. E. Allan, J. D. Cash
openaire   +3 more sources

Acute Fatty Liver of Pregnancy: A Retrospective Analysis of 56 Cases

open access: yesChinese Medical Journal, 2016
Background: Acute fatty liver of pregnancy (AFLP) is a rare but life-threatening complication occurring in the third trimester. It is often fatal to both mother and fetus.
Yan-Ping Zhang   +4 more
doaj   +1 more source

Sprayable Polymer Blends With Short‐Chain Surface Segregation for Preventing Postoperative Abdominal Adhesions

open access: yesAdvanced Healthcare Materials, EarlyView.
Adhesions’ high occurrence rates and high morbidity render them a critical challenge to be addressed. Current prevention methods, such as physical barriers, have many limitations, resulting in inconsistent safety and efficacy. This study demonstrates the potential for sprayable polymeric materials as an adhesion barrier.
Robert J. Morris III   +7 more
wiley   +1 more source

Characterizing plasmin-induced lag phase and application of PDMS microfluidics to detection of fibrinolytic activity [PDF]

open access: yes, 2018
Physical trauma is responsible for over six million deaths annually, and of these roughly 40 percent result from acute traumatic coagulopathy (ATC) occurring in the first few hours of incidence. Patients who have developed ATC have significantly improved
Ghani, Naveed
core  

Epsilon-aminocaproic acid for treatment of fibrinolysis during liver transplantation [PDF]

open access: yes, 1987
In 97 adult patients receiving liver transplants, the coagulation system was monitored by thrombelastography and by coagulation profile including PT; a PTT; platelet count; level of factors I, II, V, VII, VIII, IX, X, XI, and XII; fibrin degradation ...
Bontempo, FA   +6 more
core   +1 more source

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