Results 51 to 60 of about 3,801,413 (236)

Leptin May Promote Eosinophilic CRSwNP Progression by Enhancing Eosinophil Chemotaxis and Angiogenesis Under a Type 2 Inflammatory Milieu

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyp (CRSwNP) is a heterogeneous Type 2 inflammatory disease characterized by enhanced eosinophilic infiltration. Both innate and adaptive immunity are involved in the onset and progression of CRSwNP.
Yuki Sonoda, Yohei Sato, Yoshimasa Imoto, Mayumi Tamari, Shigeharu Fujieda   +4 more
wiley   +1 more source

Neutrophil Extracellular Traps Block Fibrinolysis in Ischemic Stroke

Annals of Neurology, EarlyView.
Objectives Intravenous thrombolysis (IVT) failure in acute ischemic stroke (AIS) is frequent, but its causes remain elusive. We investigated whether biologically relevant intrathrombus concentrations of tissue plasminogen activator (tPA) were achieved in failed IVT and whether neutrophil extracellular traps (NETs) contributed to this therapeutic ...
Mialitiana Solo Nomenjanahary, Jean‐Philippe Desilles, Fatima Zemali, Astride Perrot, Lucas Di Meglio, Sara Zalghout, Jéromine Fasille, Jérémy Neel, Stéphane Loyau, Julien Labreuche, Marie‐Charlotte Bourrienne, Dorothée Faille, François Delvoye, Véronique Ollivier, Sébastien Dupont, Jasmina Rogozarski, Nahida Brikci‐Nigassa, Robert L. Medcalf, Nadine Ajzenberg, Mikael Mazighi, Benoît Ho‐Tin‐Noé, the compoCLOT Study Group   +21 more
wiley   +1 more source

DR-70 (fibrinogen-fibrin degradation products) as a prognostic biomarker in dogs with neoplasms

Veterinary Quarterly
Fibrinogen–fibrin degradation products (DR-70) are derived from tumor cells or metastases. Our previous study reported the diagnostic values in dogs with tumors, but no research has yet to be conducted to establish DR-70 as a prognostic marker.
Chiao-Hsu Ke, Chen-Si Lin, Ka-Mei Sio, Chun-Hung Wu, Yuan-Yuan Xia, Jih-Jong Lee, Chin-Hao Hu, Cheng-Chi Liu, Bor-Song Liaw, Chiao-Lei Cheng, Keng-Hsuan Lin, Yu-Shan Wang   +11 more
doaj   +1 more source

Fibrin and Fibrinogen Degradation Products in Chronic Subdural Hematoma

Neurologia medico-chirurgica, 1975
Fibrin and fibrinogen degradation products (FDP) were examined in 30 cases of chronic subdural hematoma. Fibrinogen was not found in the contents of subdural hematoma in 29 cases, and only a small amount of fibrinogen was detected in the remaining case. The liquefied hematoma content was not coagulated by the addition of thrombin.
ITO, Haruhide, KOMAI, Toshio, YAMAMOTO, Shinjiro   +2 more
openaire   +3 more sources

Serum and Urinary Fibrin/Fibrinogen Degradation Products in Glomerulonephritis [PDF]

BMJ, 1971
The serum and urine concentrations of fibrin/fibrinogen degradation products (F.D.P.) were estimated in 172 patients with glomerulonephritis. In each case the diagnosis was established on the basis of clinical, renal histological, and ultrastructural findings. Serum F.D.P. concentrations were often raised in all types of glomerulonephritis, though more
A R, Clarkson, M K, MacDonald, J J, Petrie, J D, Cash, J S, Robson   +4 more
openaire   +2 more sources

Fundamentals, Advances, and Applications of Electrospun Nanofibrous 3D Materials

Journal of Applied Polymer Science, EarlyView.
Three‐dimensional electrospun nanofibrous systems offer unique properties and microenvironments. These properties are determined by the fabrication strategies employed and can be adjusted by the incorporation of functional additives to achieve multifunctionality for specific applications. The applications range from the biomedical to the environmental,
Rebecca Hengsbach, Viraj P. Nirwan, Altangerel Amarjargal, Zahra Asefi, Amir Fahmi   +4 more
wiley   +1 more source

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

BMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang, Yu‐zhu Wang, Yi‐fei Wang, Que Bai, Jia‐xin Hao, Zhi‐ting Li, Xiao‐qing Cao, Yu Wei, Yue Feng, Ji‐hua Chen, Franklin R. Tay, Rui‐bing Wang, Jun‐ting Gu, Li‐na Niu   +13 more
wiley   +1 more source

Clarification of fibrin generation and degradation reaction processes of clot-fibrinolysis waveform in hemorrhagic disorders.

PLoS ONE
Clot-fibrinolysis waveform analysis (CFWA) is an assay used to simultaneously evaluate coagulation and fibrinolysis reactions. Although the assay detected the reaction via transmittance changes, there was no evidence that the transmittance changes ...
Tomoko Matsumoto, Nukumi Tujii, Daiki Shimomura, Aya Kouno, Takeshi Suzuki, Sho Shinohara, Nobuo Arai, Hiroshi Kurono, Osamu Kumano, Mikio Kamioka   +9 more
doaj   +1 more source

Differences in coagulation-relevant parameters: Comparing cryoprecipitate and a human fibrinogen concentrate

PLoS ONE, 2023
Background Variable fibrinogen content within cryoprecipitate makes accurate dosing challenging in patients with coagulopathic bleeding, in addition to pathogen transmission risks associated with its administration.
Sophia Stanford, Ashok Roy, Tom Cecil, Oliver Hegener, Petra Schulz, Anna Turaj, Sean Lim, Emily Arbuthnot   +7 more
doaj  

Implantable electrochemical sensors for continuous blood monitoring

FlexMat, EarlyView.
Implantable electrochemical sensors enable direct, in situ, and continuous blood monitoring, shifting diagnosis from population‐based averages to dynamic, individualized analysis. This review systematically examines the influence of the unique blood properties on sensor design.
Kuangyi Zou, Yuanzhen Wang, Haidong Wang, Ye Zhang   +3 more
wiley   +1 more source