Results 261 to 270 of about 274,907 (333)

Kringle-Dependent Inhibition of Plasmin-Mediated Fibrinolysis by Native and Citrullinated Core Histones. [PDF]

Int J Mol Sci
Komorowicz E, Gurabi A, Wacha A, Szabó L, Ozohanics O, Kolev K.   +5 more
europepmc   +1 more source

Hyperbaric Oxygen Regulates Tumor pH to Boost Copper‐Doped Hydroxyethyl Starch Conjugate Nanoparticles Against Cancer Stem Cells

Exploration, EarlyView.
Hypoxia and acidic microenvironments are characteristic features of solid tumors, driving tumor growth, drug resistance, and metastasis. To address these issues, we combined hyperbaric oxygen therapy with rational designed hydroxyethyl starch‐doxorubicin‐copper nanoparticles to modulate the acidic microenvironment of tumors while enhancing the efficacy
Qingyuan Deng, Ao Hua, Shiyou Li, Zhijie Zhang, Xiang Chen, Qiang Wang, Xing Wang, Zhiqin Chu, Xiangliang Yang, Zifu Li   +9 more
wiley   +1 more source

Evaluation of the Effect of Phase 1 Periodontal Therapy on Serum Procoagulant State of Systemically Healthy Chronic Periodontitis Subjects: A Clinico-Biochemical Study.

J Pharm Bioallied Sci
Raje S, Banthia R, Singh P, Shrivastava A, Mehrotra N, Gupta S.   +5 more
europepmc   +1 more source

K562 Chronic Myeloid Leukemia Cells as a Dual β3-Expressing Functional Cell Line Model to Investigate the Effects of Combined αIIbβ3 and αvβ3 Antagonism. [PDF]

Methods Protoc
Elsharif AA, Patterson LH, Shnyder SD, Sheldrake HM.   +3 more
europepmc   +1 more source

Biomaterials‐Involved Construction of Extracellular Matrices for Tumor Blockade Therapy

Exploration, EarlyView.
Extracellular matrices (ECMs) play a crucial role in tumor growth and metastases by providing structural support and facilitating tumor cell proliferation. In this review, we explore the development of artificial ECMs engineered through biomineralization, fibrogenesis, and gelation. These bioinspired ECMs create a protective barrier around tumor cells,
Jinfeng Sun, Yang Liu, Jingshan Sun, Jianxun Ding, Xuesi Chen   +4 more
wiley   +1 more source

A hematologic composite score integrating iron, coagulation, and inflammation markers predicts diabetic retinopathy severity: a retrospective cross-sectional study. [PDF]

Am J Transl Res
Ma Y, Pei A, Zhao Q.
europepmc   +1 more source

Natural Products Targeting Protein Disulfide Isomerases: New Frontiers for Diabetes, Cancer, and Coagulation

Food Frontiers, EarlyView.
PDIA4 is significantly upregulated in response to nutrient overload in pancreatic β‐cells, resulting in aberrant ROS production, β‐cell failure, and diabetes. PDIA4 facilitates cancer development by inhibiting caspase‐mediatedcell death in cancer and promoting VEGF‐mediated protumoral immunity andangiogenesis in the tumor microenvironment, highlighting
Yi‐San Lee, Catherine Ortega, Tien‐Fen Kuo, Greta Yang, Wen‐Chin Yang   +4 more
wiley   +1 more source

Efficacy and safety of human fibrinogen concentrate (BT524) in patients with major haemorrhage undergoing major orthopaedic or abdominal surgery (AdFIrst): a randomised, active-controlled, multicentre, partially blinded, phase 3 non-inferiority trial. [PDF]

EClinicalMedicine
Rahe-Meyer N, Roy A, Trouillier HH, Schimo S, Wessels-Kranz J, Abraha S, Staus A, Balaban Ü, Häder T, Schüttrumpf J, Aigner S, Böhm H.   +11 more
europepmc   +1 more source

A Dual‐Mode Colorimetric‐Photothermal Immunoassay for Rapid and Sensitive Detection of Staphylococcus aureus in Real Samples

Food Safety and Health, EarlyView.
Based on the double‐antibody sandwich form, the colorimetric‐photothermal immunoassay has dual detection modes. The colorimetric detection mode was based on the absorbance intensity at 651 nm of oxTMB catalyzed by Pt@Au@Ab1, and the photothermal detection mode was based on the temperature of oxTMB under 808 nm near‐infrared (NIR) light irradiation via ...
Biao Zhang, Lingwei Huang, Enze Yue, Qingqing Li, Jia Ni, Zhaojun Ban, Xiaoyu Jia, Yufeng Wang, Weiwei Qin, Xiaoping Yu   +9 more
wiley   +1 more source