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2013
Fibrinogen is the final essential building block of the clotting process. Thus, all of the preliminary "cause and effect" events in the clotting cascade rely on the work of this molecule to measure their success. The most commonly used laboratory method for measuring fibrinogen is the Clauss fibrinogen assay.
Linda J, Stang, Lesley G, Mitchell
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Fibrinogen is the final essential building block of the clotting process. Thus, all of the preliminary "cause and effect" events in the clotting cascade rely on the work of this molecule to measure their success. The most commonly used laboratory method for measuring fibrinogen is the Clauss fibrinogen assay.
Linda J, Stang, Lesley G, Mitchell
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Archives of Biochemistry and Biophysics, 1952
Abstract The iodination of fibrinogen was investigated. Conditions were applied which favor the substitution of iodine. The iodination caused a marked change in the solubility of fibrinogen. The total amount of iodine bound was found to be equal in fibrinogen and fibrin.
Elemer Mihalyi, Koloman Laki
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Abstract The iodination of fibrinogen was investigated. Conditions were applied which favor the substitution of iodine. The iodination caused a marked change in the solubility of fibrinogen. The total amount of iodine bound was found to be equal in fibrinogen and fibrin.
Elemer Mihalyi, Koloman Laki
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Thrombosis Research, 1989
Effet d'un traitement a la pentoxifylline chez des patients atteints de maladie vasculaire peripherique au stade II, sur les taux plasmatiques de fibrinogene. Correlation entre la diminution des taux de fibrinogene et l'amelioration de l'etat de sante des patients, exprimee par le pourcentage d'augmentation de la distance parcourue a pied lors d'un ...
Philippe Bachet +2 more
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Effet d'un traitement a la pentoxifylline chez des patients atteints de maladie vasculaire peripherique au stade II, sur les taux plasmatiques de fibrinogene. Correlation entre la diminution des taux de fibrinogene et l'amelioration de l'etat de sante des patients, exprimee par le pourcentage d'augmentation de la distance parcourue a pied lors d'un ...
Philippe Bachet +2 more
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ON THE IDENTITY OF PLATELET FIBRINOGEN WITH PLASMA FIBRINOGEN [PDF]
Thrombosis and Haemostasis, 1987 It is a well established fact that fibrinogen occurs not only in blood plasma but also in the α-granules of the platelets. Recently, it has been shown that fibrinogen is synthesised in the megakaryocytes as well as in the liver. Plasma fibrinogen is derived from the liver, but platelet fibrinogen either exclusively or partially from the megakaryocytes.
A Henschen, H Kaudewitz, R E Zimmermann
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2020
Fibrinogen is a large glycoprotein, synthesized primarily in the liver. With a normal plasma concentration of 1.5-3.5 g/L, fibrinogen is the most abundant blood coagulation factor. The final stage of blood clot formation is the conversion of soluble fibrinogen to insoluble fibrin, the polymeric scaffold for blood clots that stop bleeding (a protective ...
John W. Weisel +3 more
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Fibrinogen is a large glycoprotein, synthesized primarily in the liver. With a normal plasma concentration of 1.5-3.5 g/L, fibrinogen is the most abundant blood coagulation factor. The final stage of blood clot formation is the conversion of soluble fibrinogen to insoluble fibrin, the polymeric scaffold for blood clots that stop bleeding (a protective ...
John W. Weisel +3 more
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Annual Review of Biochemistry, 1975
Fibrinogen is a soluble plasma protein that is converted to polymeric fibrin in response to damage to the vascular system. The clotting process is initiated when platelets aggregate at the wound site. Their disruption releases biologically active amines and a proteolytic cascade follows which culminates in the conversion of fibrinogen to fibrin.
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Fibrinogen is a soluble plasma protein that is converted to polymeric fibrin in response to damage to the vascular system. The clotting process is initiated when platelets aggregate at the wound site. Their disruption releases biologically active amines and a proteolytic cascade follows which culminates in the conversion of fibrinogen to fibrin.
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European Heart Journal, 1995
As evidence accumulates to implicate fibrinogen as a risk factor for cardiovascular disease (CVD) it becomes important to characterize the levels and correlates of fibrinogen in diverse populations. Knowledge of the correlates of fibrinogen may help researchers to disentangle the independent contribution of elevated fibrinogen concentrations to CVD ...
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As evidence accumulates to implicate fibrinogen as a risk factor for cardiovascular disease (CVD) it becomes important to characterize the levels and correlates of fibrinogen in diverse populations. Knowledge of the correlates of fibrinogen may help researchers to disentangle the independent contribution of elevated fibrinogen concentrations to CVD ...
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Fibrinogen Amsterdam, Another Hereditary Abnormality of Fibrinogen
British Journal of Haematology, 1971Summary. A coagulation defect, characterized by a prolonged thrombin and pro‐thrombin time, was discovered in a family without haemorrhagic diathesis. The disorder is caused by a delayed aggregation of fibrin monomers. Patient's and normal purified fibrin monomers showed the same aggregation properties, but the patient's fibrin monomers aggregated ...
J. Vreeken, Catherine L. Janssen
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Chicken Fibrinogen and Human Fibrinogen [PDF]
Thrombosis and Haemostasis, 1973 SummaryIn order to investigate the immunological features of chicken fibrinogen and to compare them with human fibrinogen, monospecific rabbit antichicken and antihuman fibrinogen antisera have been prepared. Both antisera agglutinated human tanned red cells coated with human fibrinogen.
Marie-Claude Guillin +3 more
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Fibrinogen and fibrinogen-related peptides in cancer
1984At a previous International Symposium on Plasma Protein Metabolism1 we presented evidence that patients with advanced carcinomas of the lung, pancreas and liver metabolise fibrinogen abnormally. Figure 13.1 shows the overall schema for fibrinogen synthesis, distribution and metabolism which we used to obtain that evidence2. In health, fibrinogen mainly,
Betty Kao +3 more
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