Results 231 to 240 of about 62,276 (286)
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Thrombosis and Haemostasis, 1966
Summary1. Intraocular fibrinolysis can be induced in rabbits by intravenous administration of streptokinase and plasminogen. Enhancement of intraocular fibrinolysis, however, requires a substantial increase in the fibrinolytic activity of the blood. Hence any attempt to induce therapeutic intraocular fibrinolysis by injection of fibrinolytic enzymes ...
M, Pandolfi, I M, Nilsson, J E, Niléhn
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Summary1. Intraocular fibrinolysis can be induced in rabbits by intravenous administration of streptokinase and plasminogen. Enhancement of intraocular fibrinolysis, however, requires a substantial increase in the fibrinolytic activity of the blood. Hence any attempt to induce therapeutic intraocular fibrinolysis by injection of fibrinolytic enzymes ...
M, Pandolfi, I M, Nilsson, J E, Niléhn
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Acta Haematologica, 2009
The fibrinolytic system has been studied in 12 patients with myelomatosis. Ten had some impairment of their fibrinolytic mechanisms and 4 of these had laboratory evidence of intravascular coagulation. Defective fibrinolysis may be an important factor in the pathogenesis of thromboembolicphenomena in myelomatosis.
F E, Preston, D, Lee
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The fibrinolytic system has been studied in 12 patients with myelomatosis. Ten had some impairment of their fibrinolytic mechanisms and 4 of these had laboratory evidence of intravascular coagulation. Defective fibrinolysis may be an important factor in the pathogenesis of thromboembolicphenomena in myelomatosis.
F E, Preston, D, Lee
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Chest, 1992
Fibrinolytic therapy has an expanding role in the treatment of many thromboembolic disorders. Four fibrinolytic drugs are currently marketed: streptokinase, anisoylated plasminogen-streptokinase activator complex, urokinase, and recombinant human tissue-type plasminogen activator.
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Fibrinolytic therapy has an expanding role in the treatment of many thromboembolic disorders. Four fibrinolytic drugs are currently marketed: streptokinase, anisoylated plasminogen-streptokinase activator complex, urokinase, and recombinant human tissue-type plasminogen activator.
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Blood clot contraction differentially modulates internal and external fibrinolysis
Journal of Thrombosis and Haemostasis, 2019 © 2018 International Society on Thrombosis and Haemostasis Essentials Clot contraction influences the rate of fibrinolysis in vitro. Internal fibrinolysis is enhanced ∼2-fold in contracted vs. uncontracted blood clots.
Douglas Cines +2 more
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Thrombosis Research, 1976
Abstract Many patients receiving Adriamycin (Doxorubicin hydrochloride) were noted to manifest painful subungual hemorrhages which resolved after cessation of therapy. In addition, many Adriamycin patients were noted to demonstrate elevated levels of fibrinogen/fibrin degradation products when evaluated for unrelated hemostatic defects. An evaluation
R L, Bick, L F, Fekete, W L, Wilson
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Abstract Many patients receiving Adriamycin (Doxorubicin hydrochloride) were noted to manifest painful subungual hemorrhages which resolved after cessation of therapy. In addition, many Adriamycin patients were noted to demonstrate elevated levels of fibrinogen/fibrin degradation products when evaluated for unrelated hemostatic defects. An evaluation
R L, Bick, L F, Fekete, W L, Wilson
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Thrombosis and Haemostasis, 1972
SummaryFibrinolytic activity is described in the bile of man and of several species of mammal. This activity can be precipitated from whole bile by ammonium sulphate, by acetone, and by a chlor of orm/methanol partition technique. It behaves as an anion at pH 7.4.
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SummaryFibrinolytic activity is described in the bile of man and of several species of mammal. This activity can be precipitated from whole bile by ammonium sulphate, by acetone, and by a chlor of orm/methanol partition technique. It behaves as an anion at pH 7.4.
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Acta Paediatrica, 1970
SummaryThe fibrinolytic system was studied in 207 normal fullterm newborns during the first 5 days of life. A high, but rapidly decreasing plasminogen activator activity was found during the first 4 hours in umbilical vein blood in all of the children studied.
H, Ekelund, U, Hedner, I M, Nilsson
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SummaryThe fibrinolytic system was studied in 207 normal fullterm newborns during the first 5 days of life. A high, but rapidly decreasing plasminogen activator activity was found during the first 4 hours in umbilical vein blood in all of the children studied.
H, Ekelund, U, Hedner, I M, Nilsson
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Frontiers in Bioscience, 2003
Diabetes is characterized by impaired fibrinolysis. This phenomenon reflects augmented concentrations of plasminogen activator inhibitor type-1 in tissues and in blood. The derangement appears to depend in part on elevated concentrations of free fatty acids, triglycerides, and insulin in association with the insulin resistance syndrome.
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Diabetes is characterized by impaired fibrinolysis. This phenomenon reflects augmented concentrations of plasminogen activator inhibitor type-1 in tissues and in blood. The derangement appears to depend in part on elevated concentrations of free fatty acids, triglycerides, and insulin in association with the insulin resistance syndrome.
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Best Practice & Research Clinical Haematology, 1999
The fibrinolytic system generates plasmin, which dissolves fibrin in haemostatic plugs and in thrombi. It is often regarded simply as a secondary phenomenon responsive to the generation of thrombi but it is, rather, in dynamic balance with fibrin formation, such that abnormalities in either can lead to thrombosis.
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The fibrinolytic system generates plasmin, which dissolves fibrin in haemostatic plugs and in thrombi. It is often regarded simply as a secondary phenomenon responsive to the generation of thrombi but it is, rather, in dynamic balance with fibrin formation, such that abnormalities in either can lead to thrombosis.
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British Journal of Haematology
Fibrinolysis is the process by which fibrin, the principal proteinaceous component of blood clots, is enzymatically degraded. A key event in this process is the formation of the tissue plasminogen activator (tPA)–plasminogen complex on partially degraded fibrin, which leads to the conversion of plasminogen to plasmin, which then proteolytically digests
Anton Ilich, Nigel S. Key
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Fibrinolysis is the process by which fibrin, the principal proteinaceous component of blood clots, is enzymatically degraded. A key event in this process is the formation of the tissue plasminogen activator (tPA)–plasminogen complex on partially degraded fibrin, which leads to the conversion of plasminogen to plasmin, which then proteolytically digests
Anton Ilich, Nigel S. Key
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