Novel Treatment of Staphylococcus aureus Device-Related Infections Using Fibrinolytic Agents. [PDF]
Antimicrob Agents Chemother, 2018 Staphylococcal infections involving biofilms represent a significant challenge in the treatment of patients with device-related infections. Staphylococcus aureus biofilms have been shown to be SaeRS regulated and dependent on the coagulase-catalyzed ...
Hogan S, O'Gara JP, O'Neill E.
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Combining antithrombotic and fibrinolytic agents: can it be done? [PDF]
Stroke, 2013 More than half of ischemic stroke patients who are treated with IV recombinant tissue-type plasminogen activator (rtPA) remain disabled at 3 months.1,2 The reasons are many.
Khatri P, Mono ML.
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Prospects of fibrinolytic proteases of bacteria from sea cucumber fermentation products as antithrombotic agent [PDF]
BIO Web of Conferences, 2020 Cardiovascular disease is among the largest contributors of premature mortality in the world caused by inflammation of blood vessels. The abnormalities provoke thrombus formation or thrombosis blocking blood vessels leading to strokes, heart attacks and ...
Fuad Hayatun +9 more
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Marine Drugs, 2022 Cardiovascular diseases (CVDs) have emerged as a major threat to global health resulting in a decrease in life expectancy with respect to humans. Thrombosis is one of the foremost causes of CVDs, and it is characterized by the unwanted formation of ...
Noora Barzkar +2 more
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Fibrinolytic agents for peripheral arterial occlusion. [PDF]
Cochrane Database Syst Rev, 2013 BACKGROUND Peripheral arterial thrombolysis is used in the management of peripheral arterial ischaemia. Streptokinase was originally used but safety concerns led to a search for other agents. Urokinase and recombinant tissue plasminogen activator (rt-PA)
Robertson I, Kessel DO, Berridge DC.
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Microorganisms, 2022 Fibrinolytic enzymes are the most effective agents for the treatment of thrombotic diseases. In the present study, we purified and characterized an extracellular fibrinolytic serine metalloprotease (named Velefibrinase) that is produced by marine ...
Yuting Zhou +4 more
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Nebulized fibrinolytic agents improve pulmonary fibrinolysis but not inflammation in rat models of direct and indirect acute lung injury. [PDF]
PLoS One, 2013 Background Critically ill patients frequently develop acute lung injury (ALI). Disturbed alveolar fibrin turnover, a characteristic feature of ALI, is the result of both activation of coagulation and inhibition of fibrinolysis.
Hofstra JJ +9 more
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Anti-fibrinolytic agents in post partum haemorrhage: a systematic review [PDF]
BMC Pregnancy and Childbirth, 2009 Background Post partum haemorrhage is a leading cause of maternal death worldwide. It also contributes to maternal morbidity as women may require a hysterectomy to control bleeding, or may require a blood transfusion, which can transmit viral infections.
Blackhall Karen +4 more
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Penicillium citrinum CFAM 521 Isolated From the Amazon Region: A Novel Source of a Fibrinolytic Enzyme. [PDF]
Int J MicrobiolFibrinolytic agents are essential in treating thrombosis, playing a critical role in improving survival rates in cardiovascular diseases. Microbial fibrinolytic proteases have emerged as promising alternatives due to their affordability, specificity ...
de Souza TC +9 more
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Myocardial rupture after percutaneous coronary intervention of an unstable RCA lesion in myocardial infarction and concomitant stroke treated with intravenous fibrinolytic agents: A case report. [PDF]
Clin Case Rep, 2021 Bay B +4 more
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