Combining antithrombotic and fibrinolytic agents: can it be done? [PDF]
Stroke, 2013 More than half of ischemic stroke patients who are treated with IV recombinant tissue-type plasminogen activator (rtPA) remain disabled at 3 months.1,2 The reasons are many. The IV rtPA rate of recanalizing occluded arteries is not as high as we would like, especially for large arterial occlusions, which are opened only 30% to 40% of the time.3–6 When ...
Khatri P, Mono ML.
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Prospects of fibrinolytic proteases of bacteria from sea cucumber fermentation products as antithrombotic agent [PDF]
BIO Web of Conferences, 2020 Cardiovascular disease is among the largest contributors of premature mortality in the world caused by inflammation of blood vessels. The abnormalities provoke thrombus formation or thrombosis blocking blood vessels leading to strokes, heart attacks and ...
Fuad Hayatun +9 more
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Fibrinolytic agents for peripheral arterial occlusion. [PDF]
Cochrane Database Syst Rev, 2013 Peripheral arterial thrombolysis is used in the management of peripheral arterial ischaemia. Streptokinase was originally used but safety concerns led to a search for other agents. Urokinase and recombinant tissue plasminogen activator (rt-PA) have increasingly become established as first line agents for peripheral arterial thrombolysis.
Robertson I, Kessel DO, Berridge DC.
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Anti-fibrinolytic agents in post partum haemorrhage: a systematic review [PDF]
BMC Pregnancy and Childbirth, 2009 Background Post partum haemorrhage is a leading cause of maternal death worldwide. It also contributes to maternal morbidity as women may require a hysterectomy to control bleeding, or may require a blood transfusion, which can transmit viral infections.
Blackhall Karen +4 more
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Perspective and update: intrapleural fibrinolytic therapy for pleural infections and other forms of pleural organization [PDF]
Respiratory ResearchIntrapleural fibrinolytic therapy (IPFT), also known as intrapleural enzymatic therapy (IET), has been utilized for decades to treat pleural infections by expediting drainage in patients with pleural organization.
Torry A. Tucker +2 more
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Penicillium citrinum CFAM 521 Isolated From the Amazon Region: A Novel Source of a Fibrinolytic Enzyme [PDF]
International Journal of MicrobiologyFibrinolytic agents are essential in treating thrombosis, playing a critical role in improving survival rates in cardiovascular diseases. Microbial fibrinolytic proteases have emerged as promising alternatives due to their affordability, specificity ...
Thayana Cruz de Souza +9 more
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Myocardial rupture after percutaneous coronary intervention of an unstable RCA lesion in myocardial infarction and concomitant stroke treated with intravenous fibrinolytic agents: A case report. [PDF]
Clin Case Rep, 2021 Bay B +4 more
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Oral fibrinolytic agents. [PDF]
BMJ, 1968 G. R. Fearnley, Ranjan Chakrabarti
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New horizons in the pharmacological management of venous thromboembolism. [PDF]
HemasphereAbstract Many patients suffer from venous thromboembolism (VTE) and its consequences. Despite substantial advancements with the introduction of direct oral anticoagulants (DOACs), patients and clinicians still encounter challenges in the acute and long‐term management of VTE, such as recurrent events, anticoagulant‐related bleeding complications, and ...
Verstraete A +3 more
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Indonesian Journal of Medical Laboratory Science and TechnologyThrombotic disorders are one of the leading causes of death in cardiovascular patients and contribute to the incidence of non-infectious diseases. The search for new anticoagulant agents to overcome the limitations associated with existing anticoagulant
Muhammad Ardi Afriansyah +2 more
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