Results 381 to 390 of about 1,131,844 (424)
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Epitranscriptomics in fibroblasts and fibrosis
American Journal of Physiology-Cell Physiology, 2022Fibroblasts play an important role in the pathogenic mechanisms of several socially significant diseases, including pulmonary and cardiovascular fibrosis, liver cirrhosis, systemic sclerosis, progressive kidney disease. The alterations of the epitranscriptome, including more than 170 distinct posttranscriptional RNA modifications or editing events ...
Mirolyuba Ilieva, Shizuka Uchida
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Scandinavian Journal of Rheumatology, 1988
Chronic synovitis refers to fibrin deposits on the surface of proliferating superficial synovial lining cells leading to villous hyperthrophy, and associated with foci of cell necrosis and infiltration of chronic inflammatory cells. The superficial synovial lining cells include fibroblast-like type B cells and macrophage-like type A cells.
Y T, Konttinen +6 more
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Chronic synovitis refers to fibrin deposits on the surface of proliferating superficial synovial lining cells leading to villous hyperthrophy, and associated with foci of cell necrosis and infiltration of chronic inflammatory cells. The superficial synovial lining cells include fibroblast-like type B cells and macrophage-like type A cells.
Y T, Konttinen +6 more
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Clinical and Experimental Dermatology, 2009
Fibroblastic rheumatism (FR) was first described in 1980 by Chaouat et al., and there have been few cases reported to date. The cause remains unknown. We report the first Latin-American patient with FR, to our knowledge, who is also the patient with the most striking dermatological features described in the literature.
I M L, Marconi +3 more
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Fibroblastic rheumatism (FR) was first described in 1980 by Chaouat et al., and there have been few cases reported to date. The cause remains unknown. We report the first Latin-American patient with FR, to our knowledge, who is also the patient with the most striking dermatological features described in the literature.
I M L, Marconi +3 more
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Clinical and Experimental Dermatology, 1994
The first British case of fibroblastic rheumatism is reported. Treatment with apha-interferon in combination with a reducing course of steroids resulted in some regression of the cutaneous nodules, and initial improvement in the skin fibrosis and digital contractures.
L S, Ostlere +5 more
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The first British case of fibroblastic rheumatism is reported. Treatment with apha-interferon in combination with a reducing course of steroids resulted in some regression of the cutaneous nodules, and initial improvement in the skin fibrosis and digital contractures.
L S, Ostlere +5 more
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British Medical Bulletin, 1989
The existence of fibroblast growth factors (FGFs) was proposed over 40 years ago to account for the ability of tissue extracts to stimulate fibroblast proliferation. In the 1970s it became clear that preparations containing FGF activity were in fact pleiotropic, affecting the growth and function of a wide variety of mesenchymal, endocrine and neural ...
Andrew Baird, Patricia A. Walicke
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The existence of fibroblast growth factors (FGFs) was proposed over 40 years ago to account for the ability of tissue extracts to stimulate fibroblast proliferation. In the 1970s it became clear that preparations containing FGF activity were in fact pleiotropic, affecting the growth and function of a wide variety of mesenchymal, endocrine and neural ...
Andrew Baird, Patricia A. Walicke
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Re-evaluation of fibroblasts and fibroblast-like cells
Anatomy and Embryology, 1990Scanning electron microscopic observations of connective tissue cells show a new aspect of the nature of fibroblasts, and the subsequent broad survey of references makes clear that fibroblasts of many tissues have various features which are regarded as atypical of fibroblasts, and at the same time that various connective tissue cells in different ...
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Mechanisms of joint destruction in rheumatoid arthritis — immune cell–fibroblast–bone interactions
Nature Reviews Rheumatology, 2022N. Komatsu, H. Takayanagi
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Fibroblasts in the Tumor Microenvironment
2020The implications of a tumor microenvironment in cancer initiation and progression have drawn interest in recent years. Within the tumor stroma, fibroblasts represent a predominant cell type and are responsible for the majority of extracellular components within the tumor microenvironment, such as matrix and soluble factors.
Truffi M., Sorrentino L., Corsi F.
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Reduced response of scleroderma fibroblasts to fibroblast growth factor
Archives of Dermatological Research, 1984Reactivity of scleroderma fibroblasts to lymphoid cell-derived fibroblast growth factor (FGF) was assessed in this study. The fibroblasts from the sclerotic lesion failed to respond to FGF, whereas those from scleroedematous lesions responded equally to normal fibroblast.
Shigeharu Sano +3 more
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2002
Publisher Summary Fibroblasts are the most abundant cells in the lungs. They are primarily responsible for producing the extracellular matrix proteins that maintain the structure of the airways and lung parenchyma. Myofibroblasts are found in the lamina reticularis and appear as multicellular strands.
Robin J. McAnulty, Geoffrey J. Laurent
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Publisher Summary Fibroblasts are the most abundant cells in the lungs. They are primarily responsible for producing the extracellular matrix proteins that maintain the structure of the airways and lung parenchyma. Myofibroblasts are found in the lamina reticularis and appear as multicellular strands.
Robin J. McAnulty, Geoffrey J. Laurent
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