Results 61 to 70 of about 569,034 (200)
Frontiers in Cell and Developmental Biology, 2014 Recently, the numbers of patients with non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) have increased worldwide. NAFLD and NASH are known as risk factors for liver cirrhosis and hepatocellular carcinoma.
Shizuka eMiura, Atsushi eSuzuki
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Fibroblast-organoid contacts precede organoid branching.
(A) Time-lapse snapshots of an organoid-fibroblast co-culture. Scale bar: 100 μm. (B) Detailed snapshots of 3 examples of fibroblast-organoid contact establishment in the co-cultures shown in (A) on days 1, 2, and 3.
Zuzana Sumbalova Koledova (17769092) +2 more
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Role of Fibroblast Populations in Periodontal Wound Healing and Tissue Remodeling
Frontiers in Physiology, 2019 After injury to periodontal tissues, a sequentially phased healing response is initiated that enables wound closure and partial restoration of tissue structure and function. Wound closure in periodontal tissues involves the tightly regulated coordination
Patricio C. Smith +3 more
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Endoplasmic Reticulum Stress Activation in Alport Syndrome Varies Between Genotype and Cell Type
Frontiers in Genetics, 2020 Alport syndrome is a hereditary progressive chronic kidney disease caused by mutations in type IV collagen genes COL4A3/4/5. X-linked Alport syndrome (XLAS) is caused by mutations in the COL4A5 gene and is the most common form of Alport syndrome.
Cong Wang +9 more
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Advanced ScienceHepatoblastoma, the most aggressive childhood liver tumor, poses significant challenges due to limited knowledge of its pathogenesis, particularly in poorly differentiated advanced tumors where the prognosis is dismal.
Miao Ding +12 more
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Fibroblast-induced branching requires fibroblast contractility.
(A) Maximum projection (left), detailed maximum projection (middle), and detail optical sections (right) of organoid branch induced in co-culture with fibroblasts (day 4 of dispersed culture).
Zuzana Sumbalova Koledova (17769092) +2 more
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, 2017 (A) Cell proliferation of BPH-1 cells in mono-culture. High concentrations of finasteride did not inhibit cell proliferation in mono-culture. (B) Cell proliferation of BPH-1 cells co-cultured with wild-type fibroblasts or c-Jun-/- fibroblasts.
Dongdong Fan (3746623) +5 more
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Fibroblast migration and collagen deposition during dermal wound healing: mathematical modelling and clinical implications, [PDF]
, 2006 The extent to which collagen alignment occurs during dermal wound healing determines the severity of scar tissue formation. We have modelled this using a multiscale approach, in which extracellular materials, for example collagen and fibrin, are modelled
Dallon, J. C. +7 more
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Seprase: An overview of an important matrix serine protease [PDF]
, 2008 Seprase or Fibroblast Activation Protein (FAP) is an integral membrane serine peptidase, which has been shown to have gelatinase activity. Seprase has a dual function in tumour progression.
O\u27Brien, Pamela +3 more
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BioTechniques, 2015 Skeletal muscle injury elicits the activation of satellite cells and their migration to the wound area for subsequent terminal differentiation and tissue integration. However, interstitial fibroblasts recruited to the site of injury promote deposition of
Kyle Peter Goetsch +3 more
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