Results 51 to 60 of about 569,034 (200)
Dynamic development of microglia and macrophages after spinal cord injury
Neural Regeneration ResearchSecondary injury following spinal cord injury is primarily characterized by a complex inflammatory response, with resident microglia and infiltrating macrophages playing pivotal roles.
Hu-Yao Zhou +7 more
doaj +1 more source
Human dermal fibroblast senescence in response to single and recurring oxidative stress
Frontiers in AgingIntroduction: Aging results in an accumulation of damaged cells, which reduces the health of tissues and their regenerative capabilities. In the skin, there are both internal and external drivers of oxidative stress that result in aging phenotypes ...
Tailynn Y. McCarty, Cathal J. Kearney
doaj +1 more source
The FASEB Journal, 2023 Abstract G protein‐coupled receptors (GPCRs) are the largest and most diverse class of signaling receptors. GPCRs regulate many functions in the human body and have earned the title of “most targeted receptors”. About one‐third of the commercially available drugs for various diseases target the GPCRs. Fibroblasts lay the architectural
Nidhi V. Dwivedi +6 more
openaire +3 more sources
Fibroblast-derived PI16 as a novel regulator of neuropathic pain
, 2019 Non-neuronal cells, including glia and leukocytes contribute to chronic pain. Here we identify fibroblasts secreting the protein PI16 as novel regulator of neuropathic pain.
Cobi J Heijnen (8288031) +13 more
core +2 more sources
Effect of cocoa pod husk (Theobroma cacao L.) extract on alveolar socket post tooth extraction
Dental JournalBackground: Cocoa pod husk (CPH) of Theobroma cacao L. contains tannins, alkaloids, saponins, and flavonoids triterpenoids that have antibacterial, anti-inflammatory, and antioxidant activities that can accelerate wound healing and alveolar bone ...
Yani Corvianindya Rahayu +4 more
doaj +1 more source
Impact of Cancer-Associated Fibroblast on the Radiation-Response of Solid Xenograft Tumors
Frontiers in Molecular Biosciences, 2019 Increasing evidence indicates that the heterogeneous tumor stroma supports therapy resistance at multiple levels. Fibroblasts, particularly cancer-associated fibroblasts (CAFs) are critical components of the tumor stroma.
Alizée Steer +7 more
doaj +1 more source
Semaphorin 7a participants in pterygium by regulating vascular endothelial growth factor [PDF]
International Journal of Ophthalmology, 2019 AIM: To investigate the relationship between semaphorin 7a expression and cell proliferation and migration in pterygium fibroblasts. METHODS: Twenty-six patients with surgically diagnosed pterygium were enrolled, including 15 cases of primary pterygium ...
Yun-Fei Han +9 more
doaj +1 more source
Frontiers in Oncology, 2021 This investigation was conducted to elucidate whether atractylenolide-I (ATL-1), which is the main component of Atractylodes macrocephala Koidz, can sensitize triple-negative breast cancer (TNBC) cells to paclitaxel and investigate the possible mechanism
Meng Wang +5 more
doaj +1 more source
Journal of Lipid Research, 2015 Heart failure with preserved ejection fraction (HFpEF) is half of all HF, but standard HF therapies are ineffective. Diastolic dysfunction, often secondary to interstitial fibrosis, is common in HFpEF.
Julie A. Eclov +9 more
doaj +1 more source
Modelling Protein Synthesis as A Biomarker in Fragile X Syndrome Patient-Derived Cells
Brain Sciences, 2019 The most conserved molecular phenotype of Fragile X Syndrome (FXS) is aberrant protein synthesis. This has been validated in a variety of experimental model systems from zebrafish to rats, patient-derived lymphoblasts and fibroblasts.
Rakhi Pal, Aditi Bhattacharya
doaj +1 more source