Results 31 to 40 of about 569,034 (200)

Extracellular CIRP Induces an Inflammatory Phenotype in Pulmonary Fibroblasts via TLR4

Frontiers in Immunology, 2021
Extracellular cold-inducible RNA-binding protein (eCIRP), a new damage-associated molecular pattern (DAMP), has been recently shown to play a critical role in promoting the development of bleomycin-induced pulmonary fibrosis.
Siavash Bolourani, Siavash Bolourani, Siavash Bolourani, Ezgi Sari, Max Brenner, Max Brenner, Max Brenner, Max Brenner, Ping Wang, Ping Wang, Ping Wang, Ping Wang   +11 more
doaj   +1 more source

Heterogenecity of fibroblasts

Journal of Oral and Maxillofacial Pathology, 2011
Fibroblasts are a major stromal cell type present in human connective tissue maintaining the structural integrity in health. Depending on the situation, location and various conditions, fibroblasts exhibit considerable variation in morphology, size and shape that suggest the existence of discrete cellular subsets.
Ravikanth, Manyam, Soujanya, P, Manjunath, K, Saraswathi, TR, Ramachandran, CR   +4 more
openaire   +3 more sources

Functional dissection of the "Drosophila melanogaster" fibroblast growth factor signalling pathway in branching morphogenesis of the developing tracheal system [PDF]

, 2004
Fibroblast Growth Factor (FGF) signalling is involved in numerous developmental processes ranging from cell determination to mitogenesis, and cell survival to cell migration.
Dossenbach, Caroline
core   +1 more source

Studies on the treatment of malignant tumors with fibroblast-inhibiting agent III. Effects of chloroquine on human cancers [PDF]

, 1964
A fibroblast-inhibiting agent, chloroquine, used in the treatment of animal tumors led to a reasonably good result, and this approach was extended to the treatment of human cancers.
Kimura, Ikuro, Hiraki, Kiyoshi
core   +1 more source

KIF1C and new Huntingtin-interacting protein 1 binding proteins regulate rheumatoid arthritis fibroblast-like synoviocytes’ phenotypes

Frontiers in Immunology
BackgroundHuntingtin-interacting protein-1 (HIP1) is a new arthritis severity gene implicated in the regulation of the invasive properties of rheumatoid arthritis (RA) fibroblast-like synoviocytes (FLS).
Teresina Laragione, Carolyn Harris, Percio S. Gulko   +2 more
doaj   +1 more source

Effects of Different Titanium Anodized Surfaces on Peri-Implant Soft Tissue Healing Around Dental Abutments: In Vitro and Proteomic Study

Applied Sciences
Objectives: This study aimed to evaluate the effects of different titanium (Ti) anodized surfaces on soft tissue healing around dental implant abutments.
Francisco Romero-Gavilán, Andreia Cerqueira, Carlos Arias-Mainer, David Peñarrocha-Oltra, Claudia Salavert-Martínez, Juan Carlos Bernabeu-Mira, Iñaki García-Arnáez, Félix Elortza, Mariló Gurruchaga, Isabel Goñi, Julio Suay   +10 more
doaj   +1 more source

Direct Conversion of Human Fibroblasts into Adipocytes Using a Novel Small Molecular Compound: Implications for Regenerative Therapy for Adipose Tissue Defects

Cells, 2021
There is a need in plastic surgery to prepare autologous adipocytes that can be transplanted in patients to reconstruct soft tissue defects caused by tumor resection, including breast cancer, and by trauma and other diseases. Direct conversion of somatic
Yoshihiro Sowa, Tsunao Kishida, Fiona Louis, Seiji Sawai, Makoto Seki, Toshiaki Numajiri, Kenji Takahashi, Osam Mazda   +7 more
doaj   +1 more source

Small Molecule Cocktails Promote Fibroblast-to-Leydig-like Cell Conversion for Hypogonadism Therapy

Pharmaceutics, 2023
Male hypogonadism arises from the inadequate production of testosterone (T) by the testes, primarily due to Leydig cell (LC) dysfunction. Small molecules possess several advantages, including high cell permeability, ease of synthesis, standardization ...
Fei Yuan, Kaiping Bai, Yanping Hou, Xiangyu Zou, Jie Sun   +4 more
doaj   +1 more source

Fibroblast-growth-factor-23 in heart failure with preserved ejection fraction: relation to exercise capacity and outcomes

, 2020
AimsThis study aimed to assess plasma fibroblast growth factor 23 (FGF23) in patients with heart failure with preserved ejection fraction (HFpEF) and its relation to inflammation, renal function, clinical and imaging characteristics, exercise capacity ...
JN Khan (7756580), P Kanagala (7717895), IB Squire (7717910), M Eltayeb (9441314), GP McCann (7687148), LL Ng (7717913), JR Arnold (7717907), P Gupta (7703555), A Singh (7717904), GS Gulsin (7708124)   +9 more
core   +5 more sources

Cardiac fibroblasts regulate myocardium and coronary vasculature development in the murine heart via the collagen signaling pathway

eLife
The fibroblast (FB), cardiomyocyte (CM), and vascular endothelial cell (Vas_EC) are the three major cell types in the heart, yet their relationships during development are largely unexplored. To address this gap, we employed RNA staining of the FB marker
Yiting Deng, Yuanhang He, Juan Xu, Haoting He, Manling Zhang, Guang Li   +5 more
doaj   +1 more source