Results 11 to 20 of about 746,101 (309)

Developmentally regulated expression of integrin alpha-6 distinguishes neural crest derivatives in the skin

Frontiers in Cell and Developmental Biology, 2023
Neural crest-derived cells play essential roles in skin function and homeostasis. However, how they interact with environmental cues and differentiate into functional skin cells remains unclear.
Shize Ma, Shize Ma, Xiu Li, Xiu Li, Rui Cao, Rui Cao, Guoqin Zhan, Guoqin Zhan, Xin Fu, Xin Fu, Ran Xiao, Ran Xiao, Zhigang Yang, Zhigang Yang   +13 more
doaj   +1 more source

The effect of helper virus on Abelson virus-induced transformation of lymphoid cells [PDF]

, 1978
Abelson murine leukemia virus (A-MuLV)-transformed fibroblast nonproducer cells were used to prepare A-MuLV stocks containing a number of different helper viruses.
Baltimore, David, Rosenberg, Naomi
core   +2 more sources

Klotho Modulates Pro-Fibrotic Activities in Human Atrial Fibroblasts through Inhibition of Phospholipase C Signaling and Suppression of Store-Operated Calcium Entry

Biomedicines, 2022
Background: Atrial fibroblasts activation causes atrial fibrosis, which is one major pathophysiological contributor to atrial fibrillation (AF) genesis.
Yuan Hung, Cheng-Chih Chung, Yao-Chang Chen, Yu-Hsun Kao, Wei-Shiang Lin, Shih-Ann Chen, Yi-Jen Chen   +6 more
doaj   +1 more source

Teflon Injection into the Trachea Causes Predictable Fibroblastic Response and Collagen Deposition: A Pilot Study. [PDF]

, 2016
BackgroundExpiratory central airway collapse is an increasingly recognized abnormality of the central airways and may be present in as many as 22% of patients evaluated for chronic obstructive pulmonary disease and/or asthma.
Baxter, Boiselle, Bolliger, Bolot, Chertin, Chertin, Dedo, Eisner, Ernst, Ernst, Feist, Ferguson, Fujiwara, Gilkeson, Ikeda, Iwamoto, Johnson, Jokinen, Jokinen, Kirchner, Lehman, Majid, Murgu, Noppen, Nuutinen, Palombini, Susanto, Wright, Zhang   +28 more
core   +1 more source

Understanding Fibroblast Heterogeneity in Form and Function

Biomedicines, 2023
Historically believed to be a homogeneous cell type that is often overlooked, fibroblasts are more and more understood to be heterogeneous in nature. Though the mechanisms behind how fibroblasts participate in homeostasis and pathology are just beginning
Jennifer B. Parker, Caleb Valencia, Deena Akras, Sarah E. DiIorio, Michelle F. Griffin, Michael T. Longaker, Derrick C. Wan   +6 more
doaj   +1 more source

Tackling MARCKS-PIP3 circuit attenuates fibroblast activation and fibrosis progression. [PDF]

, 2019
Targeting activated fibroblasts, including myofibroblast differentiation, has emerged as a key therapeutic strategy in patients with idiopathic pulmonary fibrosis (IPF).
Chen, Ching-Hsien, Last, Jerold A, Li, Ji-Min, Oldham, Justin, Phan, Sem H, Wu, Reen, Xu, Jihao, Yang, David C   +7 more
core   +2 more sources

Functional roles of CD26/DPP4 in bleomycin‐induced pulmonary fibrosis

Physiological Reports, 2023
The pathogenesis of pulmonary fibrosis involves complex interplay between cell types and signaling pathways. Recurrent alveolar epithelial injury can occur during pulmonary inflammation, causing dysregulation of epithelial repair.
Yu Koyanagi, Takeshi Kawasaki, Yoshitoshi Kasuya, Ryo Hatano, Shun Sato, Yukiko Takahashi, Kei Ohnuma, Chikao Morimoto, Steven M. Dudek, Koichiro Tatsumi, Takuji Suzuki   +10 more
doaj   +1 more source

CVD and COVID-19: Emerging Roles of Cardiac Fibroblasts and Myofibroblasts

Cells, 2022
Cardiovascular disease (CVD) is the leading cause of death worldwide. Current data suggest that patients with cardiovascular diseases experience more serious complications with coronavirus disease-19 (COVID-19) than those without CVD. In addition, severe
Laxmansa C. Katwa, Chelsea Mendoza, Madison Clements   +2 more
doaj   +1 more source

Lysine-Specific Demethylase 4D Is Critical for the Regulation of the Cell Cycle and Antioxidant Capacity in Goat Fibroblast Cells

Biology, 2023
Oxidative damage to skin fibroblast cells is a causative factor in many skin diseases. Previous studies have reported that lysine-specific demethylase 4D (Kdm4d) is involved in DNA replication, but its role on antioxidant capacity remains unclear. In the
Xiaowei Chen, Yingnan Yang, Yu Cai, Hua Yang, Feng Wang, Mingtian Deng   +5 more
doaj   +1 more source

Extinction of tyrosine aminotransferase gene activity in somatic cell hybrids involves modification and loss of several essential transcription factors [PDF]

, 1993
Extinction is defined as the loss of cell type-specific gene expression that occurs in somatic cell hybrids derived by fusion of cells with dissimilar phenotypes.
Boshart, Michael, Nitsch, Doris, Schütz, Günther   +2 more
core   +1 more source