Results 1 to 10 of about 444,923 (265)
Journal of Lipid Research, 2015 Heart failure with preserved ejection fraction (HFpEF) is half of all HF, but standard HF therapies are ineffective. Diastolic dysfunction, often secondary to interstitial fibrosis, is common in HFpEF.
Julie A. Eclov +9 more
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Modelling Protein Synthesis as A Biomarker in Fragile X Syndrome Patient-Derived Cells
Brain Sciences, 2019 The most conserved molecular phenotype of Fragile X Syndrome (FXS) is aberrant protein synthesis. This has been validated in a variety of experimental model systems from zebrafish to rats, patient-derived lymphoblasts and fibroblasts.
Rakhi Pal, Aditi Bhattacharya
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Frontiers in Cell and Developmental Biology, 2014 Recently, the numbers of patients with non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) have increased worldwide. NAFLD and NASH are known as risk factors for liver cirrhosis and hepatocellular carcinoma.
Shizuka eMiura, Atsushi eSuzuki
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Role of Fibroblast Populations in Periodontal Wound Healing and Tissue Remodeling
Frontiers in Physiology, 2019 After injury to periodontal tissues, a sequentially phased healing response is initiated that enables wound closure and partial restoration of tissue structure and function. Wound closure in periodontal tissues involves the tightly regulated coordination
Patricio C. Smith +3 more
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Endoplasmic Reticulum Stress Activation in Alport Syndrome Varies Between Genotype and Cell Type
Frontiers in Genetics, 2020 Alport syndrome is a hereditary progressive chronic kidney disease caused by mutations in type IV collagen genes COL4A3/4/5. X-linked Alport syndrome (XLAS) is caused by mutations in the COL4A5 gene and is the most common form of Alport syndrome.
Cong Wang +9 more
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Indian Journal of Rheumatology, 2017 Fibroblastic rheumatism (FR) is a rare dermoarthopathy reported from different parts of the world since 1980. Although the exact cause is unknown, few reports implicate infection may be a triggering event. Patients usually present with multiple skin nodules and polyarthropathy with progressive skin contractures.
openaire +2 more sources
The role of fibroblasts and fibroblast‐derived factors in periprosthetic osteolysis [PDF]
Arthritis & Rheumatism, 2006 AbstractObjectiveThis study was undertaken to investigate how fibroblasts respond to stimulation with particulate wear debris and/or conditioned media obtained from pathologic tissue, and whether these activated fibroblasts express compounds that are involved in bone resorption.MethodsConditioned media from explant cultures of synovial tissue ...
Tamas, Koreny +5 more
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Advanced ScienceHepatoblastoma, the most aggressive childhood liver tumor, poses significant challenges due to limited knowledge of its pathogenesis, particularly in poorly differentiated advanced tumors where the prognosis is dismal.
Miao Ding +12 more
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BioTechniques, 2015 Skeletal muscle injury elicits the activation of satellite cells and their migration to the wound area for subsequent terminal differentiation and tissue integration. However, interstitial fibroblasts recruited to the site of injury promote deposition of
Kyle Peter Goetsch +3 more
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The Effect of Non Freeze-dried Hydrogel-CHA on Fibroblast Proliferation
Journal of Dentistry Indonesia, 2015 Bone damage can be caused by variety of surgical procedures. Bone reconstruction has been developed lately is tissue engineering techniques. One of materials that proved to be effective as a scaffold in tissue engineering is a hydrogel.
Ivan Arie Wahyudi +1 more
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