Results 91 to 100 of about 78,520,259 (248)

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Developmental Therapeutics for Alveolar Generation and Regeneration: Implications for Bronchopulmonary Dysplasia and Prematurity-Associated Lung Disease

Cells
The mechanisms by which alveoli form during lung development remain under investigation. The classical model proposes formation through secondary septation, whereas an alternative proposed model suggests that alveoli arise through epithelial budding ...
David Warburton, Rex Moats, Lance A. Parton, Edmund F. LaGamma, Victoria Niklas   +4 more
doaj   +1 more source

Fibroblast growth factor 10 ameliorates neurodegeneration in mouse and cellular models of Alzheimer's disease via reducing tau hyperphosphorylation and neuronal apoptosis. [PDF]

Aging Cell, 2023
Guo K, Huang W, Chen K, Huang P, Peng W, Shi R, He T, Zhang M, Wang H, Hu J, Wang X, Shentu Y, Xu H, Lin L.   +13 more
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Fibroblast growth factor 10 protects against UVB-induced skin injury by activating the ERK/YAP signalling pathway. [PDF]

Cell Prolif, 2022
Wang N, Dong Y, Xu X, Shen Y, Huang Z, Yu Y, Liu Z, Gong W, Zhang S, Zheng Y, Song Y, Zhu Z, Jin L, Cong W.   +13 more
europepmc   +1 more source

Human Fibroblast Growth Factor 9 Induces Hair Follicle Cycle Transition via TGF-β/BMP/Smad Pathway [PDF]

Bowen Zhang,1,2 Xue He,1,2 Yaxin Guo,1,2 Shengnan Zhao,1,2 Jing Lan,1,2 Fuqiang Chen,1,2 Long Wan,3 Haishan Tian,4 Xuegang Xu1,2 1Department of Dermatology, The First Hospital of China Medical University, Shenyang, People’s Republic of China; 2Key ...
Zhao S, Guo Y, Tian H, He X, Wan L, Chen F, Xu X, Zhang B, Lan J   +8 more
core  

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Accelerated wound closure in vitro by fibroblasts from a subgroup of cleft lip/palate patients: role of transforming growth factor-α.

PLoS ONE, 2014
In a fraction of patients surgically treated for cleft lip/palate, excessive scarring disturbs maxillary growth and dento-alveolar development. Since certain genes are involved in craniofacial morphogenesis as well as tissue repair, a primary defect ...
Joël Beyeler, Isabelle Schnyder, Christos Katsaros, Matthias Chiquet   +3 more
doaj   +1 more source

Role of FGF10/FGFR2b Signaling in Mouse Digestive Tract Development, Repair and Regeneration Following Injury

Frontiers in Cell and Developmental Biology, 2019
During embryonic development, the rudimentary digestive tract is initially a tube-like structure. It is composed of epithelial cells surrounded by mesenchymal cells.
Yu-Qing Lv, Yu-Qing Lv, Jin Wu, Xiao-Kun Li, Xiao-Kun Li, Jin-San Zhang, Jin-San Zhang, Saverio Bellusci, Saverio Bellusci, Saverio Bellusci   +9 more
doaj   +1 more source