Results 101 to 110 of about 78,520,259 (248)

The binding of NCAM to FGFR1 induces a specific cellular response mediated by receptor trafficking [PDF]

, 2009
Neural cell adhesion molecule (NCAM) associates with fibroblast growth factor (FGF) receptor-1 (FGFR1). However, the biological significance of this interaction remains largely elusive.
Vladimir Berezin, Gerhard Christofori, Christofori, Gerhard, Francavilla, Chiara; id_orcid, Paola Cattaneo, Cattaneo, Paola, Ugo Cavallaro, Cavallaro, Ugo, de Marco, Ario, Francavilla, Chiara, Ami, Diletta, Berezin, Vladimir, Ario de Marco, Chiara Francavilla, Bock, Elisabeth, Elisabeth Bock, Diletta Ami, Ami Diletta, Christofori Gerhard, De Marco A., Cattaneo Paola, Berezin Vladimir, Cavallaro Ugo, Ami D., De Marco Ario, Christofori G., Bock E., Francavilla C., Cattaneo P., Cavallaro U., Bock Elisabeth, Francavilla Chiara, Berezin V.   +32 more
core   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Effect of Fibroblast Growth Factor 10 and an Interacting Non-Coding RNA on Secondary Hair Follicle Dermal Papilla Cells in Cashmere Goats' Follicle Development Assessed by Whole-Transcriptome Sequencing Technology. [PDF]

Animals (Basel), 2023
Gao Y, Song W, Hao F, Duo L, Zhe X, Gao C, Guo X, Liu D.   +7 more
europepmc   +1 more source

Functional dissection of the "Drosophila melanogaster" fibroblast growth factor signalling pathway in branching morphogenesis of the developing tracheal system [PDF]

, 2004
Fibroblast Growth Factor (FGF) signalling is involved in numerous developmental processes ranging from cell determination to mitogenesis, and cell survival to cell migration.
Dossenbach, Caroline
core   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Bronchial Variation: Anatomical Abnormality May Predispose Chronic Obstructive Pulmonary Disease

International Journal of COPD, 2021
Xian Wen Sun,1,2 Ying Ni Lin,1,2 Yong Jie Ding,1,2 Shi Qi Li,1,2 Hong Peng Li,1,2 Qing Yun Li1,2 1Department of Respiratory and Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic ...
Sun XW, Lin YN, Ding YJ, Li SQ, Li HP, Li QY   +5 more
doaj  

Basic fibroblast growth factor and fibroblast growth factor receptors in adult olfactory epithelium

, 2001
Basic fibroblast growth factor (FGF2) stimulates proliferation of the globose basal cells, the neuron:ll precursor in the olfactory epithelium. The present study investigates the expression of basic fibroblast growth factor and fibroblast growth factor ...
Pickles, J. O., Mackay-Sim, A, James O Pickles, Kyra Sneesby, Pi-en Hsu, Yu, F, Feron, F., Mackay-Sim, A., François Féron, Hsu, P, Sneesby, K, Sneesby, K., Alan Mackay-Sim, Yu, F., Fu Yu, Pickles, JO, Feron, F, Hsu, P.   +17 more
core   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

Enhanced effect of fibroblast growth factor-2-containing dalteparin/protamine nanoparticles on hair growth

, 2016
Yuki Takabayashi,1 Masaki Nambu,1 Masayuki Ishihara,2 Masahiro Kuwabara,1 Koichi Fukuda,2 Shingo Nakamura,2 Hidemi Hattori,2Tomoharu Kiyosawa1 1Department of Plastic and Reconstructive Surgery, 2Division of Biomedical ...
Nambu M, Fukuda K, Hattori H, Kiyosawa T, Kuwabara M, Takabayashi Y, Ishihara M, Nakamura S   +7 more
core  

Participants’ characteristics by categories of plasma Fibroblast growth factor 23.

, 2019
Participants’ characteristics by categories of plasma Fibroblast growth factor 23.
Eustasius Musenge (6519407), Vakhtang Rekhviashvili (6714389), Therese Dix-Peek (6714386), Bala Waziri (6714383), Graham Paget (5814971), Saraladevi Naicker (5814980), Raquel Duarte (3124080), Caroline Dickens (3594077)   +7 more
core   +1 more source