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Fibroblast growth factor 23 as a phosphotropic hormone and beyond
Journal of Bone and Mineral Metabolism, 2011Fibroblast growth factor 23 (FGF23) is produced by bone and reduces serum phosphate by inhibiting proximal tubular phosphate reabsorption and intestinal phosphate absorption. Excess actions of FGF23 cause several kinds of hypophosphatemic rickets/osteomalacia while deficient actions of FGF23 result in hyperphosphatemic tumoral calcinosis.
Seiji, Fukumoto, Yuichiro, Shimizu
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Fibroblast Growth Factor-23 and Phosphorus Metabolism
2011The understanding of phosphorus metabolism has expanded considerably over the last decade. Recent studies have identified a novel bone-kidney endocrine axis that maintains phosphate homeostasis. When phosphate is in excess, FGF-23 is secreted from bone and acts on the kidney to promote phosphate excretion into urine and to suppress vitamin D synthesis,
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The couple fibroblast growth factor 23 (FGF23)/Klotho
Annales de biologie clinique, 2015The fibrobalst growth factor 23 (FGF23) is a protein secreted in the plasma by bone cells. FGF23 controls phosphate and calcitriol plasma concentration. Its main physiological targets are the kidney and the parathyroid gland. Its production is stimulated by phosphate intake and plasma calcitriol levels.
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Fibroblast Growth Factor 2—A Review of Stabilisation Approaches for Clinical Applications
Pharmaceutics, 2020Cornelia Locher +2 more
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The Role of Fibroblast Growth Factor 23 in Sepsis
Critical Care Medicine, 2014Narat, Srivali +2 more
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Fibroblast Growth Factor 23 and Left Ventricular Hypertrophy in Chronic Kidney Disease
Circulation, 2009Gutierrez Om +2 more
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Involvement of the Fibroblast Growth Factor System in Adaptive and Chemokine-Induced Arteriogenesis
Circulation Research, 2003Francisco Borja Fernández Corujo +2 more
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Fibroblast Growth Factor 23 and CKD Prognosis
American Journal of Kidney Diseases, 2012Navdeep, Tangri, Andrew S, Levey
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