Results 31 to 40 of about 255,577 (258)

Fibroblast growth factor 23 levels before and after renal transplantation

open access: yesThe Egyptian Journal of Internal Medicine, 2016
Background Fibroblast growth factor 23 (FGF23), a novel bone-derived hormone that inhibits phosphate reabsorption and calcitriol production by the kidney, has uncovered primary regulatory pathways and new systems biology governing bone mineralization ...
Mohamed M El-khatib   +4 more
doaj   +1 more source

Dietary vitamin D3 deprivation suppresses fibroblast growth factor 23 signals by reducing serum phosphorus levels in laying hens

open access: yesAnimal Nutrition, 2022
The present study was carried out to evaluate the effect of dietary supplemental vitamin D3 on fibroblast growth factor 23 (FGF23) signals as well as phosphorus homeostasis and metabolism in laying hens.
Jiakun Yan   +8 more
doaj   +1 more source

Lymphangioleiomyomatosis: circulating levels of FGF23 and pulmonary diffusion [PDF]

open access: yesJornal Brasileiro de Pneumologia, 2023
Objective: Lymphangioleiomyomatosis (LAM) is a rare, destructive disease of the lungs with a limited number of determinants of disease activity, which are a critical need for clinical trials.
Anthony J Esposito   +9 more
doaj   +1 more source

Cardiac actions of fibroblast growth factor 23 [PDF]

open access: yesBone, 2017
Fibroblast growth factors (FGF) are mitogenic signal mediators that induce cell proliferation and survival. Although cardiac myocytes are post-mitotic, they have been shown to be able to respond to local and circulating FGFs. While precise molecular mechanisms are not well characterized, some FGF family members have been shown to induce cardiac ...
openaire   +2 more sources

Fibroblast Growth Factor 23 and Klotho in AKI [PDF]

open access: yesSeminars in Nephrology, 2019
Acute kidney injury (AKI) is associated with many of the same mineral metabolite abnormalities that are observed in chronic kidney disease. These include increased circulating levels of the osteocyte-derived, vitamin D-regulating hormone, fibroblast growth factor 23 (FGF23), and decreased renal expression of klotho, the co-receptor for FGF23.
Marta, Christov   +3 more
openaire   +2 more sources

FGF-23 (Fibroblast Growth Factor-23) and Cardiorenal Interactions

open access: yesCirculation: Heart Failure, 2021
Background: Animal models implicate FGF-23 (fibroblast growth factor-23) as a direct contributor to adverse cardiorenal interactions such as sodium avidity, diuretic resistance, and neurohormonal activation, but this has not been conclusively demonstrated in humans.
Juan B. Ivey-Miranda   +15 more
openaire   +4 more sources

Higher plasma fibroblast growth factor 23 levels are associated with a higher risk profile in pulmonary arterial hypertension

open access: yesPulmonary Circulation, 2019
Metabolic abnormalities are proposed to contribute to pulmonary arterial as well as right ventricular remodelling in pulmonary arterial hypertension. Among the proposed abnormalities are altered glucose and lipid processing, mitochondrial malfunction ...
Habib Bouzina   +2 more
doaj   +1 more source

Effect of intravenous iron on endogenous erythropoietin and FGF-23 secretion in patients with chronic kidney disease

open access: yesRenal Failure, 2023
Introduction It has been observed that intravenous iron administration may suppress endogenous production of erythropoietin (EPO). We postulate that this effect may be mediated by increased FGF-23 secretion.Aim of the study To evaluate the short-term ...
Katarzyna Muras-Szwedziak   +2 more
doaj   +1 more source

Fibroblast growth factor 23: the making of a hormone [PDF]

open access: yesKidney International, 2006
Fibroblast growth factor 23 (FGF23) modulates serum phosphate and 1alpha,25-dihydroxyvitamin D3 levels. FGF23 expression is in turn regulated by 1alpha,25-dihydroxyvitamin D3 and dietary phosphate load, and is strikingly elevated during renal progression.
openaire   +2 more sources

Osteocytes and the pathogenesis of hypophosphatemic rickets

open access: yesFrontiers in Endocrinology, 2022
Since phosphorus is a component of hydroxyapatite, its prolonged deprivation affects bone mineralization. Fibroblast growth factor 23 (FGF23) is essential for maintaining phosphate homeostasis and is mainly produced by osteocytes.
Miwa Yamazaki, Toshimi Michigami
doaj   +1 more source

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