Fibroblast Growth Factor 23 and the Last Mile [PDF]
Clinical Journal of the American Society of Nephrology, 2020 Fibroblast growth factor 23 (FGF23) is a bone-derived hormone that regulates phosphorus balance by enhancing urinary phosphorus excretion and inhibiting the synthesis of 1,25-dihydroxyvitamin D [1,25(OH)2D] ([1][1]).
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Fibroblast Growth Factor 23 [PDF]
Journal of the American Society of Nephrology, 2005 Although phosphate is important in skeletal mineralization, energy metabolism, and multiple enzymatic processes, little has been understood about the regulation of phosphate in health and disease until recently.
Erik A. Imel, Michael J. Econs
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Estimated glomerular filtration rate is a poor predictor of the concentration of middle molecular weight uremic solutes in chronic kidney disease [PDF]
, 2012 Background: Uremic solute concentration increases as Glomerular Filtration Rate (GFR) declines. Weak associations were demonstrated between estimated GFR (eGFR) and the concentrations of several small water-soluble and protein-bound uremic solutes ...
Barreto, Daniela V +9 more
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Cell Sequence and Mitosis Affect Fibroblast Directional Decision-Making during Chemotaxis in Tissue-Mimicking Microfluidic Mazes [PDF]
Pham, Q.L., Rodrigues, L.N., Maximov, M.A. et al. Cel. Mol.
Bioeng. (2018), 2017 Directed fibroblast migration is central to highly proliferative processes in regenerative medicine and developmental biology, such as wound healing and embryogenesis. However, the mechanisms by which single fibroblasts affect each other's directional decisions, while chemotaxing in microscopic tissue pores, are not well understood.
arxiv +1 more source
A redox-responsive hyaluronic acid-based hydrogel for chronic wound management [PDF]
, 2021 Polymer-based hydrogels have been widely applied for chronic wound therapeutics, due to their well-acclaimed wound exudate management capability. At the same time, there is still an unmet clinical need for simple wound diagnostic tools to assist clinical decision-making at the point of care and deliver on the vision of patient-personalised wound ...
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Fibroblast growth factor 23 and cardiovascular disease in patients with chronic kidney disease [PDF]
, 2018 Chronic kidney disease (CKD) has been known to be associated with an increased risk of cardiovascular (CV) mortality and morbidity in Japan. Although traditional risk factors contribute to the development of CV disease in CKD patients, they cannot fully ...
NITTA Kosaku
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Intravenous phosphate loading increases fibroblast growth factor 23 in uremic rats. [PDF]
PLoS ONE, 2014 Oral phosphate loading and calcitriol stimulate Fibroblast growth factor 23 (FGF23) secretion, but the mechanisms underlying the stimulation of FGF23 remain to be studied.
Noriko Arai-Nunota +10 more
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Renal Failure, 2023 Introduction It has been observed that intravenous iron administration may suppress endogenous production of erythropoietin (EPO). We postulate that this effect may be mediated by increased FGF-23 secretion.Aim of the study To evaluate the short-term ...
Katarzyna Muras-Szwedziak +2 more
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Expression of basic fibroblast growth factor is associated with poor outcome in non-Hodgkin's lymphoma [PDF]
It is now clear that angiogenesis and angiogenesis factors are important in the pathogenesis of haematological malignancies. High pretreatment levels of serum basic fibroblast growth factor have been shown to be associated with poor prognosis in patients
A Bikfalvi +28 more
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Predictors of intact and C-terminal fibroblast growth factor 23 in Gambian children [PDF]
, 2013 Elevated C-terminal fibroblast growth factor 23 (C-FGF23) concentrations have been reported in Gambian children with and without putative Ca-deficiency rickets.
Assar, Shima +4 more
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