Results 1 to 10 of about 243,507 (261)
Upstream Regulators of Fibroblast Growth Factor 23 [PDF]
Frontiers in Endocrinology, 2021 Fibroblast growth factor 23 (FGF23) has been described as an important regulator of mineral homeostasis, but has lately also been linked to iron deficiency, inflammation, and erythropoiesis. FGF23 is essential for the maintenance of phosphate homeostasis
Danielle M. A. Ratsma +2 more
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Physiological Actions of Fibroblast Growth Factor-23 [PDF]
Frontiers in Endocrinology, 2018 Fibroblast growth factor-23 (FGF23) is a bone-derived hormone suppressing phosphate reabsorption and vitamin D hormone synthesis in the kidney. At physiological concentrations of the hormone, the endocrine actions of FGF23 in the kidney are αKlotho ...
Reinhold G. Erben
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Fibroblast Growth Factor-23—A Potential Uremic Toxin [PDF]
Toxins, 2016 Fibroblast growth factor-23 (FGF23) is a circulating member of the FGF family produced mainly by the osteocytes and osteoblasts that can act as a hormone.
Piotr Kuczera +2 more
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A Case of Hyperphosphatemia and Elevated Fibroblast Growth Factor 23: A Brief Review of Hyperphosphatemia and Fibroblast Growth Factor 23 Pathway [PDF]
Kidney International Reports, 2017 Phosphate homeostasis is a complex process involving communication among bones, kidneys, and other organ systems.1, 2 This is tightly regulated through parathyroid hormone (PTH) and bone-derived fibroblast growth factor 23 (FGF23).1, 2, 3 Disruption of either pathway has been associated with a number of disorders resulting in hypo- or hyperphosphatemia.
Joseph Wang +6 more
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Fibroblast Growth Factor 23 and Sarcopenia in Maintenance Haemodialysis Population [PDF]
Journal of Cachexia, Sarcopenia and MuscleBackground Sarcopenia is defined as the loss of muscle mass, strength, and/or performance. It is strongly associated with all‐cause mortality. Fibroblast growth factor 23 (FGF23) is markedly elevated in patients with chronic kidney disease, especially ...
Limy Wong +5 more
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Phosphate and fibroblast growth factor 23 in diabetes [PDF]
Clinical Science, 2021 AbstractDiabetes is associated with a strongly elevated risk of cardiovascular disease, which is even more pronounced in patients with diabetic nephropathy. Currently available guideline-based efforts to correct traditional risk factors are only partly able to attenuate this risk, underlining the urge to identify novel treatment targets.
Amarens van der Vaart +4 more
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Frontiers in Medicine, 2023 IntroductionA negative association between C-terminal fibroblast growth factor 23 (cFGF23) and hemoglobin (Hb) levels has been reported in patients with predialysis chronic kidney disease.
Yu-Wei Fang +9 more
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Fibroblast Growth Factor 23 [PDF]
Journal of the American Society of Nephrology, 2005 Although phosphate is important in skeletal mineralization, energy metabolism, and multiple enzymatic processes, little has been understood about the regulation of phosphate in health and disease until recently.
Erik A, Imel, Michael J, Econs
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Biochemistry and Biophysics Reports, 2021 Fibroblast growth factor (FGF) 23 produced by the bone is the principal hormone to regulate serum phosphate level. Serum FGF23 needs to be tightly regulated to maintain serum phosphate in a narrow range.
Yuichi Takashi +8 more
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Tumor-induced osteomalacia: Easing the diagnosis with fibroblast growth factor 23
APIK Journal of Internal Medicine, 2022 Tumor-induced osteomalacia (TIO), is a rare paraneoplastic syndrome resulting in bone pain, muscle weakness, and recurrent fractures. Hypophosphatemia, hyperphosphaturia, low 1, 25 dihydroxyVitamin D, and normal serum calcium are noted.
Mala Dharmalingam, Lohit Kumbar
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