Results 1 to 10 of about 405,619 (302)

Upstream Regulators of Fibroblast Growth Factor 23 [PDF]

Frontiers in Endocrinology, 2021
Fibroblast growth factor 23 (FGF23) has been described as an important regulator of mineral homeostasis, but has lately also been linked to iron deficiency, inflammation, and erythropoiesis. FGF23 is essential for the maintenance of phosphate homeostasis
Danielle M. A. Ratsma, M. Carola Zillikens, Bram C. J. van der Eerden   +2 more
doaj   +3 more sources

Fibroblast Growth Factor 23 and Sarcopenia in Maintenance Haemodialysis Population [PDF]

Journal of Cachexia, Sarcopenia and Muscle
Background Sarcopenia is defined as the loss of muscle mass, strength, and/or performance. It is strongly associated with all‐cause mortality. Fibroblast growth factor 23 (FGF23) is markedly elevated in patients with chronic kidney disease, especially ...
Limy Wong, Rachel Kenny, Jenny Y. Y. Ooi, Yung Shing Tsang, Emily Schembri, Lawrence P. McMahon   +5 more
doaj   +2 more sources

Impact of Vitamin D Supplementation on Arterial Vasomotion, Stiffness and Endothelial Biomarkers in Chronic Kidney Disease Patients [PDF]

, 2014
Background: Cardiovascular events are frequent and vascular endothelial function is abnormal in patients with chronic kidney disease (CKD). We demonstrated endothelial dysfunction with vitamin D deficiency in CKD patients; however the impact of ...
A Herbelin, A Recio-Mayoral, A Suessenbacher, AC Borges, AD Gepner, AK Uzum, AS Go, B Kestenbaum, B scamps-Latscha, C Drechsler, C Faul, C Turner, DA Procsal, David Goldsmith, Debasish Banerjee, F Stam, FJ Barrat, FK Timimi, Frances Boa, Geeta Hampson, H Dobnig, J Deanfield, J Yeboah, JA Sugden, JA Suwaidi, JH Bae, JP Halcox, JS Sidhu, JS Sidhu, Juan Carlos Kaski, K Muller, Laura Tooth, M Froicu, M Kanbay, M Tonelli, M Wolf, MD Witham, MD Witham, MD Witham, MI Yilmaz, MS Wong, N Chitalia, Nihil Chitalia, OM Gutierrez, OM Gutierrez, P Chandra, P Leventis, RA Harris, S Pilz, S Shab-Bidar, SI Sokol, TJ Anderson, Tuan Ismail, WD Fraser, Yiqing Song, YR Lou   +55 more
core   +21 more sources

High intact fibroblast growth factor 23 levels associated with low hemoglobin levels in patients on chronic hemodialysis

Frontiers in Medicine, 2023
IntroductionA negative association between C-terminal fibroblast growth factor 23 (cFGF23) and hemoglobin (Hb) levels has been reported in patients with predialysis chronic kidney disease.
Yu-Wei Fang, Yu-Wei Fang, Jing-Tong Wang, Tzu Yun Lin, Chung-Jen Lee, Tsrang-Neng Jang, Tsrang-Neng Jang, Ming-Hsien Tsai, Ming-Hsien Tsai, Hung-Hsiang Liou   +9 more
doaj   +1 more source

Skeletal FGFR1 signaling is necessary for regulation of serum phosphate level by FGF23 and normal life span

Biochemistry and Biophysics Reports, 2021
Fibroblast growth factor (FGF) 23 produced by the bone is the principal hormone to regulate serum phosphate level. Serum FGF23 needs to be tightly regulated to maintain serum phosphate in a narrow range.
Yuichi Takashi, Shun Sawatsubashi, Itsuro Endo, Yukiyo Ohnishi, Masahiro Abe, Munehide Matsuhisa, Daiji Kawanami, Toshio Matsumoto, Seiji Fukumoto   +8 more
doaj   +1 more source

Tumor-induced osteomalacia: Easing the diagnosis with fibroblast growth factor 23

APIK Journal of Internal Medicine, 2022
Tumor-induced osteomalacia (TIO), is a rare paraneoplastic syndrome resulting in bone pain, muscle weakness, and recurrent fractures. Hypophosphatemia, hyperphosphaturia, low 1, 25 dihydroxyVitamin D, and normal serum calcium are noted.
Mala Dharmalingam, Lohit Kumbar
doaj   +1 more source

Effects of Single Vitamin D Injection (200,000 Units) on Serum Fibroblast Growth Factor 23 and Sclerostin Levels in Subjects with Vitamin D Deficiency [PDF]

Endocrinology and Metabolism, 2017
BackgroundVitamin D deficiency remains common in all age groups and affects skeletal and non-skeletal health. Fibroblast growth factor 23 is a bone-derived hormone that regulates phosphate and 1,25-dihydroxyvitamin D homeostasis as a counter regulatory ...
Dongdong Zhang, Da Hea Seo, Han Seok Choi, Hye-Sun Park, Yoon-Sok Chung, Sung-Kil Lim   +5 more
doaj   +1 more source

Evocalcet with vitamin D receptor activator treatment for secondary hyperparathyroidism

PLoS ONE, 2022
This ad hoc analysis of a previously conducted phase 3 head-to-head comparison study of evocalcet and cinacalcet in secondary hyperparathyroidism patients undergoing maintenance hemodialysis evaluated the efficacy and safety of combined once-daily oral ...
Takashi Shigematsu, Shinji Asada, Yuichi Endo, Takehisa Kawata, Masafumi Fukagawa, Tadao Akizawa   +5 more
doaj   +2 more sources

Il Fibroblast Growth Factor-23 (FGF-23)

Giornale di Clinica Nefrologia e Dialisi, 2018
Negli ultimi due decenni, l'identificazione delle proprietà biologiche del Fibroblast Growth Factor 23 (FGF23) ha notevolmente ampliato le conoscenze sulla regolazione endocrina e paracrina dell'omeostasi dei fosfati e sulle relazioni intercorrenti tra ...
D. Rendina, G. De Filippo, R. Muscariello, F. De Pascale, P. Strazzullo   +4 more
doaj   +1 more source

Neurofibromatosis type 1 associated with hypophosphatemic osteomalacia due to hypersecretion of fibroblast growth factor 23: a case report

Journal of Medical Case Reports, 2020
Background Neurofibromatosis type 1 is characterized by multiple café au lait spots and cutaneous and plexiform neurofibromas, and is one of the most common autosomal dominant hereditary disorders caused by mutations of the neurofibromatosis type 1 tumor
Takahiko Obo, Nobuyuki Koriyama, Akinori Tokito, Kazuma Ogiso, Yoshihiko Nishio   +4 more
doaj   +1 more source