Results 31 to 40 of about 405,619 (302)
Fibroblast Growth Factor 23 and the Last Mile [PDF]
Clinical Journal of the American Society of Nephrology, 2020 Fibroblast growth factor 23 (FGF23) is a bone-derived hormone that regulates phosphorus balance by enhancing urinary phosphorus excretion and inhibiting the synthesis of 1,25-dihydroxyvitamin D [1,25(OH)2D] ([1][1]).
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A rare cause of atraumatic fractures: case series of four patients with tumor-induced osteomalacia
Clinical Diabetes and Endocrinology, 2020 Background Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome that presents with hypophosphatemia, bone pain, muscle weakness and fractures.
Debbie W. Chen +4 more
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Role of Fibroblast Growth Factor 23 (FGF23) and αKlotho in Cancer
Frontiers in Cell and Developmental Biology, 2021 Together with fibroblast growth factors (FGFs) 19 and 21, FGF23 is an endocrine member of the family of FGFs. Mainly secreted by bone cells, FGF23 acts as a hormone on the kidney, stimulating phosphate excretion and suppressing formation of 1,25(OH)2D3 ...
Franz Ewendt +2 more
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Effects of etelcalcetide on fibroblast growth factor 23 in patients with secondary hyperparathyroidism receiving hemodialysis [PDF]
, 2019 Background: Etelcalcetide is an intravenous calcimimetic approved for treatment of secondary hyperparathyroidism (sHPT) in patients receiving hemodialysis. Besides lowering parathyroid hormone (PTH), etelcalcetide also significantly reduces fibroblast
Block, Geoffrey A. +9 more
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Fibroblast growth factor 23 and bone mineralisation [PDF]
International Journal of Oral Science, 2015 Fibroblast growth factor 23 (FGF23) is a hormone that is mainly secreted by osteocytes and osteoblasts in bone. The critical role of FGF23 in mineral ion homeostasis was first identified in human genetic and acquired rachitic diseases and has been further characterised in animal models.
Guo, Yu-Chen, Yuan, Quan
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Fibroblast-growth factor 23 promotes terminal differentiation of ATDC5 cells. [PDF]
PLoS ONE, 2017 Fibroblast Growth Factor 23 (FGF23) is well documented as a crucial player in the systemic regulation of phosphate homeostasis. Moreover, loss-of-function experiments have revealed that FGF23 also has a phosphate-independent and local impact on ...
Mathilde Guibert +3 more
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Serum fibroblast growth factor 23, serum iron and bone mineral density in premenopausal women [PDF]
, 2016 Fibroblast growth factor 23 (FGF23) circulates as active protein and inactive fragments. Low iron status increases FGF23 gene expression, and iron deficiency is common. We hypothesized that in healthy premenopausal women, serum iron influences C-terminal
Acton, Anthony +7 more
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Frontiers in Physiology, 2020 Dietary phosphorus oversupply wastes non-renewable natural resources and raises environmental concerns in animal agriculture. We hypothesized that laying hens do not need large safety margins for dietary phosphorus because of the existence of fibroblast ...
Zhouzheng Ren +8 more
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Lymphangioleiomyomatosis: circulating levels of FGF23 and pulmonary diffusion [PDF]
Jornal Brasileiro de Pneumologia, 2023 Objective: Lymphangioleiomyomatosis (LAM) is a rare, destructive disease of the lungs with a limited number of determinants of disease activity, which are a critical need for clinical trials.
Anthony J Esposito +9 more
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Fibroblast growth factor 23 and cardiovascular disease in patients with chronic kidney disease [PDF]
, 2018 Chronic kidney disease (CKD) has been known to be associated with an increased risk of cardiovascular (CV) mortality and morbidity in Japan. Although traditional risk factors contribute to the development of CV disease in CKD patients, they cannot fully ...
NITTA Kosaku
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