Fibroblast growth factor 23: fueling the fire [PDF]
Kidney International, 2016 In chronic kidney disease, systemic inflammation is common and associated with mortality. The present study demonstrates that fibroblast growth factor 23 (FGF23) contributes to uremic inflammation by increasing hepatic expression and secretion of inflammatory cytokines.
Hanudel, Mark +2 more
openaire +6 more sources
Fibroblast-growth-factor-23 in heart failure with preserved ejection fraction: relation to exercise capacity and outcomes [PDF]
, 2020 AimsThis study aimed to assess plasma fibroblast growth factor 23 (FGF23) in patients with heart failure with preserved ejection fraction (HFpEF) and its relation to inflammation, renal function, clinical and imaging characteristics, exercise capacity ...
JN Khan (7756580) +9 more
core +7 more sources
Significance of Fibroblast Growth Factor 23 in Acute Kidney Injury [PDF]
Acta Clinica Croatica, 2015 Acute kidney injury is a clinical syndrome associated with increased patient morbidity and mortality, as well as serious short-term and long-term consequences, especially in the perioperative period.
Nikolina Bašić-Jukić +5 more
doaj +2 more sources
Effects of Single Vitamin D Injection (200,000 Units) on Serum Fibroblast Growth Factor 23 and Sclerostin Levels in Subjects with Vitamin D Deficiency [PDF]
Endocrinology and Metabolism, 2017 BackgroundVitamin D deficiency remains common in all age groups and affects skeletal and non-skeletal health. Fibroblast growth factor 23 is a bone-derived hormone that regulates phosphate and 1,25-dihydroxyvitamin D homeostasis as a counter regulatory ...
Dongdong Zhang +5 more
doaj +1 more source
Fibroblast Growth Factor 23 in CKD: Getting Closer to Prime Time? [PDF]
Clin J Am Soc NephrolWan M, Querfeld U, Schaefer F, Shroff R.
europepmc +3 more sources
Regulation of human fibroblast insulin-like growth factor (IGF)-binding proteins by IGF-1 and cytokines, mechanisms of action and effects upon IGF bioactivity [PDF]
, 1995 PhDThe insulin-like growth factors, IGF-I and IGF-II, are ubiquitous polypeptide molecules that have mitogenic and metabolic actions in a wide variety of cell types, and consequently play a major role in mammalian growth and development.
Yateman, Martin Edward
core +4 more sources
Multiple faces of fibroblast growth factor-23 [PDF]
Current Opinion in Nephrology and Hypertension, 2016 This review examines the role of fibroblast growth factor-23 (FGF-23) in mineral metabolism, innate immunity and adverse cardiovascular outcomes.FGF-23, produced by osteocytes in bone, activates FGFR/α-Klotho (α-Kl) complexes in the kidney. The resulting bone-kidney axis coordinates renal phosphate reabsorption with bone mineralization, and creates a ...
Xiaobin, Han, L Darryl, Quarles
openaire +2 more sources
Evocalcet with vitamin D receptor activator treatment for secondary hyperparathyroidism
PLoS ONE, 2022 This ad hoc analysis of a previously conducted phase 3 head-to-head comparison study of evocalcet and cinacalcet in secondary hyperparathyroidism patients undergoing maintenance hemodialysis evaluated the efficacy and safety of combined once-daily oral ...
Takashi Shigematsu +5 more
doaj +2 more sources
Il Fibroblast Growth Factor-23 (FGF-23)
Giornale di Clinica Nefrologia e Dialisi, 2018 Negli ultimi due decenni, l'identificazione delle proprietà biologiche del Fibroblast Growth Factor 23 (FGF23) ha notevolmente ampliato le conoscenze sulla regolazione endocrina e paracrina dell'omeostasi dei fosfati e sulle relazioni intercorrenti tra ...
D. Rendina +4 more
doaj +1 more source
Fibroblast Growth Factor 23 and Inflammation in CKD [PDF]
Clinical Journal of the American Society of Nephrology, 2012 Summary Background and objectives Levels of fibroblast growth factor 23 (FGF23) and inflammatory markers are commonly elevated in CKD, and each is associated with adverse clinical outcomes. This study tested the hypothesis that FGF23 is independently associated with inflammation in CKD.
Jair, Munoz Mendoza +14 more
openaire +2 more sources