Results 221 to 230 of about 230,861 (252)

Motor deficits in fibroblast growth factor receptor-3 null mutant mice

Behavioural Pharmacology, 2001
Fibroblast growth factor receptor-3 (FGFR-3) regulates aspects of bone development. Mutations in the FGFR-3 gene (Fgfr3) in humans and mice produce vertebral abnormalities and bone deformities. The present study evaluated the behavioural concomitants of the Fgfr3-/- mutation.
M P, McDonald, K M, Miller, C, Li, C, Deng, J N, Crawley   +4 more
openaire   +2 more sources

[Mutations of the fibroblast growth factor receptor 3 gene in achondroplasia].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, 1999
To evaluate whether mutation in the exon 10 of the fibroblast growth factor receptor 3(FGFR3) gene in common in Chinese patients with achondroplasia.Genomic DNA from seven sporadic cases of achondroplasia was studied by using PCR-SSCP and restriction enzymes.All patients carried the same glycine-to-arginine mutation at codon 380(G380R) of the ...
P, Zhao, H, Ma, Y, Wang, Z, Mi, Y, Wu, M, Jiang, H, Gao, Y, Li   +7 more
openaire   +1 more source

Mutations in fibroblast growth factor receptor 2 and fibroblast growth factor receptor 3 genes associated with human gastric and colorectal cancers.

Cancer research, 2001
Autosomal dominant disorders of skeletal and cranial development have been linked to fibroblast growth factor receptor (FGFR) 2 and FGFR3. Here we report two identical mutations in FGFR2 that cause craniosynostosis syndromes, Crouzon, Apert, and Pfeiffer in gastric carcinoma.
J H, Jang, K H, Shin, J G, Park
openaire   +1 more source

Systemic therapy for hormone receptor-positive/human epidermal growth factor receptor 2-negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Hope Rugo, Özge Gümüşay, Laura A Huppert   +2 more
exaly  

Regulation of chondrocyte growth and differentiation by fibroblast growth factor receptor 3.

Novartis Foundation symposium, 2001
Both gain-of-function and loss-of-function mutations in fibroblast growth factor receptor 3 (Fgfr3) have revealed unique roles for this receptor during skeletal development. Loss-of-function alleles of Fgfr3 lead to an increase in the size of the hypertrophic zone, delayed closure of the growth plate and the subsequent overgrowth of long bones. Gain-of-
openaire   +1 more source

Hypochondroplasia: Molecular Analysis of the Fibroblast Growth Factor Receptor 3 Gene

Annals of the New York Academy of Sciences, 1996
G A, Bellus, I, McIntosh, J, Szabo, A, Aylsworth, I, Kaitila, C A, Francomano   +5 more
openaire   +2 more sources

Fibroblast growth factor receptor signalling dysregulation and targeting in breast cancer

Open Biology, 2022
Chiara Francavilla
exaly  

Fibroblast Growth Factor Receptor 3 and Multiple Myeloma

2008
Victor Hugo Jiménez-Zepeda, A. Keith Stewart   +1 more
openaire   +1 more source

The potential of fibroblast growth factor/fibroblast growth factor receptor signaling as a therapeutic target in tumor angiogenesis

Expert Opinion on Therapeutic Targets, 2015
Roberto Ronca, Marco Rusnati, Marco Presta   +2 more
exaly  

Fibroblast Growth Factor Receptor 1 and Related Ligands in Small-Cell Lung Cancer

Journal of Thoracic Oncology, 2015
Rafal Dziadziuszko, Hui Yu, Liping Zhang
exaly