Results 241 to 250 of about 194,657 (287)

Geometrically Controlled WNT Activation Drives Intestinal Morphogenesis

Advanced Healthcare Materials, EarlyView.
Crypt‐villi‐like morphogenesis can be driven and controlled via architectural patterns in colorectal cells with the use of digital light processing printing. The resulting mini tissues exhibit budding structures and functionality, as evidenced by increased mucin expression.
Nathaniel C. Burmas, Arlyn M. Fabian, Amoli Vanavadiya, Quinton Smith   +3 more
wiley   +1 more source

Development of a Modular Ribonucleoprotein Complex as a General Strategy to Deliver RNAi Therapeutics

Advanced Healthcare Materials, EarlyView.
A modular and customizable RNAi therapeutics delivery platform composed of a pseudosymmetric human RNA binding protein‐siRNA complex (SmiRNP) is developed. By fusing a targeting module and an endosomal escape peptide onto the delivery platform, SmiRNP successfully delivered siRNA to silence the KRAS oncogene in a colorectal carcinoma cell line, leading
Nok Yin Tam, Xiaoqi Wang, Grace Chung Yan Chan, Wai Po Kong, Wai Yin Chau, Xiuqiong Fu, Kwok‐Yin Wong, Hong Lok Lung, Zhi‐Ling Yu, Wei Shen Aik   +9 more
wiley   +1 more source

Redox Biology and Insulin-like Growth Factor-Binding Protein-6: A Potential Relationship. [PDF]

Biology (Basel)
Coda ARD, Liso A, Bellanti F.
europepmc   +1 more source

Molecular Biology of ACL Graft Healing: Early Mechanical Loading Perspective. [PDF]

Orthop Rev (Pavia)
Kacprzak B.
europepmc   +1 more source

The Role of Fibroblasts in Melanoma Development: From Tumor Microenvironment Remodeling to Pre-Metastatic Niche Formation. [PDF]

Int J Mol Sci
Belviso I, Pastore R, Mileo A, Del Genio E, Boccia S, Palermi S, Sellitto C, Motti ML.   +7 more
europepmc   +1 more source

Feasibility analysis of Sinomenine alleviating fibrosis of filtering bleb after glaucoma filtering surgery: a mini review. [PDF]

Front Med (Lausanne)
Xun X, Liu X, Zhou P, Wu C, Peng Q.
europepmc   +1 more source

Activation of the fibroblast growth factor receptor 3 in bladder cancer

, 2007
openaire   +1 more source

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Fibroblast growth factor receptor-3 in urothelial tumorigenesis

Urologic Oncology: Seminars and Original Investigations, 2013
Fibroblast growth factor receptor-3 (FGFR3) is a receptor tyrosine kinase implicated in the tumorigenesis of multiple malignancies, including bladder and other urothelial cancers, multiple myeloma, and cervical cancer. In urothelial carcinoma (UC), constitutive receptor activation occurs most commonly through substitution of a wild-type residue with ...
Matthew I. Milowsky, Gopa Iyer, Gopa Iyer   +2 more
openaire   +3 more sources

Mutations of the Fibroblast Growth Factor Receptor-3 Gene in Achondroplasia

Hormone Research, 1996
Achondroplasia (ACH), the most common cause of chondrodysplasia in man (1 in 15,000 live births), is an autosomal dominant condition of unknown origin characterized by short-limbed dwarfism and macrocephaly. Recently, a gene for ACH has been mapped to chromosome 4p16.3.
J. Bonaventure, Anna Pelet, Arnold Munnich, Pierre Maroteaux, Laurence Legeai-Mallet, François Rousseau, M. Le Merrer, Jean-Michel Rozet   +7 more
openaire   +3 more sources